Dr Rebecca San Gil

Postdoctoral Research Fellow

Queensland Brain Institute

r.sangil@uq.edu.au

Featured projects	Duration
Genome-wide CRISPR screening for modifiers of diverse cellular phenotypes Genome Innovation Hub Collaborative Project (UQ infrastructure)	2019
Optimised bioinformatics and validation pipeline for genome-wide CRISPR screening data Genome Innovation Hub Collaborative Project (UQ infrastructure)	2021

Publications

Journal Articles (8)

Journal Articles

San Gil, Rebecca (2020). First person - Rebecca San Gil. Journal of Cell Science, 133 (15) jcs251918, 1-2. doi: 10.1242/jcs.251918

Gil, R. San, Cox, D., McAlary, L., Berg, T., Walker, A. K., Yerbury, J. J., Ooi, L. and Ecroyd, H. (2020). Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells. Journal of Cell Science, 133 (15), 1-15. doi: 10.1242/jcs.243709

Hedl, Thomas J., San Gil, Rebecca, Cheng, Flora, Rayner, Stephanie L., Davidson, Jennilee M., De Luca, Alana, Villalva, Maria D., Ecroyd, Heath, Walker, Adam K. and Lee, Albert (2019). Proteomics approaches for biomarker and drug target discovery in ALS and FTD. Frontiers in Neuroscience, 13 (JUN) 548, 548. doi: 10.3389/fnins.2019.00548

Clarke, Benjamin E., Gil, Rebecca San, Yip, Jing, Kalmar, Bernadett and Greensmith, Linda (2019). Regional differences in the inflammatory and heat shock response in glia: implications for ALS. Cell Stress and Chaperones, 24 (5), 857-870. doi: 10.1007/s12192-019-01005-y

Cox, Dezerae, Whiten, Daniel R., Brown, James W. P., Horrocks, Mathew H., San Gil, Rebecca, Dobson, Christopher M., Klenerman, David, van Oijen, Antoine M. and Ecroyd, Heath (2018). The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity. Journal of Biological Chemistry, 293 (12), 4486-4497. doi: 10.1074/jbc.m117.813865

San Gil, Rebecca, Ooi, Lezanne, Yerbury, Justin J. and Ecroyd, Heath (2017). The heat shock response in neurons and astroglia and its role in neurodegenerative diseases. Molecular Neurodegeneration, 12 (1) 65. doi: 10.1186/s13024-017-0208-6

San Gil, Rebecca, Berg, Tracey and Ecroyd, Heath (2017). Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells. Scientific Reports, 7 (1) 2387. doi: 10.1038/s41598-017-02459-9

Whiten, D. R., San Gil, R., McAlary, L., Yerbury, J. J., Ecroyd, H. and Wilson, M. R. (2016). Rapid flow cytometric measurement of protein inclusions and nuclear trafficking. Scientific Reports, 6 (1) 31138. doi: 10.1038/srep31138

Areas of research

CRISPR/Gene editing

Short read/Next Gen sequencing