Research
Gene editing
The Genome Innovation Hub continually develops a number of protocols and procedures while undertaking our collaborative projects. Below are a selection of detailed developments useful to researchers undertaking Gene editing procedures in the laboratory.
Developments
| Featured projects | Duration |
|---|---|
|
Identification and exploitation of genome landing pads for cattle. Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2022 |
|
Optimised bioinformatics and validation pipeline for genome-wide CRISPR screening data Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2021 |
|
Expanding the scope of multimodal single cell sequencing Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2021 |
|
HTS single cell CRISPR technology for experimental validation of population genetics and functional genomics discovery Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2021 |
|
OmniCRISPR: a simultaneous and combinatorial approach to the generation of multiple precise genomic alterations Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2020 |
|
Simultaneous identification of RNA-chromatin interactions and transcriptomes in single cells Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2020 |
|
Using transposon-sequencing to probe whole cell protein-protein interactions Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
|
Genome-wide CRISPR screening for modifiers of diverse cellular phenotypes Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
|
Precise genome editing Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
|
Dual gRNA screen Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
Publications
Meredith A. Redd, PhD; Sarah E. Scheuer, MD; Natalie J. Saez, PhD; Yusuke Yoshikawa, MD, PhD; Han Sheng Chiu, MS; Ling Gao, PhD; Mark Hicks, PhD; Jeanette E. Villanueva, PhD; Yashutosh Joshi, MD; Chun Yuen Chow, PhD; Gabriel Cuellar-Partida, PhD; Jason N. Peart, PhD; Louise E. See Hoe, PhD; Xiaoli Chen, PhD; Yuliangzi Sun, MS; Jacky Y. Suen, PhD; Robert J. Hatch, PhD; Ben Rollo, PhD; Di Xia, PhD; Mubarak A.H. Alzubaidi, PhD; Snezana Maljevic, PhD; Gregory A. Quaife-Ryan, PhD; James E. Hudson, PhD; Enzo R. Porrello, PhD; Melanie Y. White, PhD; Stuart J. Cordwell, PhD; John F. Fraser, MD, PhD; Steven Petrou, PhD; Melissa E. Reichelt, PhD; Walter G. Thomas, PhD; Glenn F. King, PhD; Peter S. Macdonald, MD, PhD; Nathan J. Palpant, PhD
doi: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001020
Harriet P. Lo, Ye-Wheen Lim, Zherui Xiong, Nick Martel, Charles Ferguson, Nicholas Ariotti, Jean Giacomotto, James Rae, Matthias Floetenmeyer, Shayli Varasteh Moradi, Ya Gao, Vikas A. Tillu, Di Xia, Huang Wang, Samira Rahnama, Susan J. Nixon, Michele Bastiani, Ryan D. Day, Kelly A. Smith, Nathan J. Palpant, Wayne A. Johnston, Kirill Alexandrov, Brett M. Collins, Thomas E. Hall, Robert G. Parton; Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. J Cell Biol 6 December 2021; 220 (12): e201905065.
