Professor John Hooper

Featured projects	Duration
Nanopore sequencing of DNA from extracellular vesicles Genome Innovation Hub Collaborative Project (UQ infrastructure)	2023

Clements, Judith A., Hooper, John D. and Dong, Ying (2013). The Human Tissue Kallikrein and Kallikrein-related Peptidase Family. Handbook of Proteolytic Enzymes. (pp. 2747-2756) edited by Neil D. Rawlings and Guy Salvesen. London, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-382219-2.00606-2

Ramsay, Andrew J., Kwarciak, Agnieszka, Hooper, John D., Lopez-Otin, Carlos and Velasco, Gloria (2013). Matriptase-2. Handbook of proteolytic enzymes. (pp. 2975-2983) edited by Neil D. Rawlings and Guy Salvensen. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-382219-2.00650-5

Hollenberg, M.D. and Hooper, John David (2012). Kallikrein-related peptidases (KLKs), Proteinase-mediated Signalling and Proteinase-activated receptors (PARs). Kallikrein-related peptidases Volume 1, Characterization, regulation, and interactions within the protease web. (pp. 373-398) edited by Viktor Magdolen, Christian Sommerhoff, Hans Fritz and Manfred Schmitt. Berlin Germany: DeGruyter.

Bennett, Nigel C., Hooper, John and Gobe, Glenda C. (2012). Endogenous strategies for steroidogenesis and androgen signalling in prostate cancer cells. Androgens: production, functions and disorders. (pp. 99-114) edited by Berkley F. Thompson and Devon J. Robinson. New York, NY, United States: Nova Science Publishers.

Hollenberg, Morley D., Hooper, John D., Darmoul, Dalila and Oikonomopoulou, Katerina (2012). Kallikrein-related peptidases (KLKs), Proteinase-mediated signaling and proteinase-activated receptors (PARs). Characterization, regulation, and interactions within the protease web. (pp. 373-398) Berlin, Germany: De Gruyter Mouton.

Clements, J. A., Hooper, John David, Odorico, D. M. and Dong, Y. (2004). The tissue kallikrein gene cluster. Handbook of Proteolytic Enzymes / 1. Aspartic and metallo peptidases. (pp. 478-478) edited by Barrett, A. J., Rawlings, N. D. and Woessner, J. F.. Amsterdam, The Netherlands: Elsevier Academic Press.

Yang, Haotian, Wang, Haolu, He, Yaowu, Yang, Yang, Thompson, Erik W., Xia, Di, Burke, Leslie J., Cao, Lu, Hooper, John D., Roberts, Michael S., Crawford, Darrell H.G. and Liang, Xiaowen (2024). Identification and characterization of TM4SF1+ tumor self-seeded cells. Cell Reports, 43 (7) 114512, 114512. doi: 10.1016/j.celrep.2024.114512

McGahan, William, Gough, Madeline, Liu, Cheng, Hoyte, Sharon, Gill, Anthony J., Cavallucci, David, Hooper, John D., Thomas, Paul A., Cooper, Caroline, O'Rourke, Thomas, Butler, Nick, Yeung, Shinn, Kryza, Thomas, Gulhane, Brook, Latter, Melissa J., Waddell, Nicola, Samra, Jaswinder S., Simpson, Fiona and Pajic, Marina (2024). Fibroblast activation protein (FAP) is overexpressed on both stromal and epithelial cells prior to pancreatic ductal adenocarcinoma: implications for early diagnosis on 68Ga-FAPI-PET/CT. Gastroenterology, 167 (6), 1217-1220. doi: 10.1053/j.gastro.2024.06.033

Khanabdali, Ramin, Mandrekar, Michelle, Grygiel, Rick, Vo, Phuoc-an, Palma, Carlos, Nikseresht, Sara, Barton, Siena, Shojaee, Mozhgan, Bhuiyan, Sadman, Asari, Kartini, Belzer, Susan, Ansari, Khairul, Coward, Jermaine I, Perrin, Lewis, Hooper, John, Guanzon, Dominic, Lai, Andrew, Salomon, Carlos, Kershner, Kevin, Newton, Christine, Horejsh, Douglas and Rice, Gregory (2024). High throughput Surface Epitope Immunoaffinity Isolation of Extracellular Vesicles and Downstream Analysis. Biology Methods and Protocols, 9 (1) ARTN bpae032, bpae032. doi: 10.1093/biomethods/bpae032

Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2024). Estimation of risk posed by malignant polyps amongst colorectal surgeons in Australia and New Zealand. Annals of Coloproctology, 40 (1), 114-120. doi: 10.3393/ac.2023.00178.0025

Shah, Esha T., Molloy, Christopher, Gough, Madeline, Kryza, Thomas, Samuel, Selwin G., Tucker, Amos, Bhatia, Maneet, Ferguson, Genevieve, Heyman, Rebecca, Vora, Shivam, Monkman, James, Bolderson, Emma, Kulasinghe, Arutha, He, Yaowu, Gabrielli, Brian, Hooper, John D., Richard, Derek J., O’Byrne, Kenneth J. and Adams, Mark N. (2024). Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells. British Journal of Cancer, 130 (7), 1196-1205. doi: 10.1038/s41416-024-02584-z

Harrington, Brittney S., Kamdar, Rahul, Ning, Franklin, Korrapati, Soumya, Caminear, Michael W., Hernandez, Lidia F., Butcher, Donna, Edmondson, Elijah F., Traficante, Nadia, Hendley, Joy, Gough, Madeline, Rogers, Rebecca, Lourie, Rohan, Shetty, Jyoti, Tran, Bao, Elloumi, Fathi, Abdelmaksoud, Abdalla, Nag, Madhu Lal, Mazan-Mamczarz, Krystyna, House, Carrie D., Hooper, John D. and Annunziata, Christina M. (2023). UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer. Journal of Experimental and Clinical Cancer Research, 42 (1) 270, 270. doi: 10.1186/s13046-023-02820-z

Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Schreiber, Veronika, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron E. (2023). Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer. Histopathology, 83 (4), 647-656. doi: 10.1111/his.15000

McGuckin, Michael A., Davies, Julie M., Felgner, Pascal, Wong, Kuan Yau, Giri, Rabina, He, Yaowu, Moniruzzaman, Md., Kryza, Thomas, Sajiir, Haressh, Hooper, John D., Florin, Timothy H., Begun, Jakob, Oussalah, Abderrahim, Hasnain, Sumaira Z., Hensel, Michael and Sheng, Yong H. (2023). MUC13 cell surface mucin limits Salmonella Typhimurium infection by protecting the mucosal epithelial barrier. Cellular and Molecular Gastroenterology and Hepatology, 16 (6), 985-1009. doi: 10.1016/j.jcmgh.2023.08.011

Koistinen, Hannu, Kovanen, Ruusu‐Maaria, Hollenberg, Morley D., Dufour, Antoine, Radisky, Evette S., Stenman, Ulf‐Håkan, Batra, Jyotsna, Clements, Judith, Hooper, John D., Diamandis, Eleftherios, Schilling, Oliver, Rannikko, Antti and Mirtti, Tuomas (2023). The roles of proteases in prostate cancer. IUBMB Life, 75 (6), 493-513. doi: 10.1002/iub.2700

Dutt, Mriga, Hartel, Gunter, Richards, Renee S., Shah, Alok K., Mohamed, Ahmed, Apostolidou, Sophia, Gentry‐Maharaj, Aleksandra, Hooper, John D., Perrin, Lewis C., Menon, Usha, Hill, Michelle M. and Australian Ovarian Cancer Study Group (2023). Discovery and validation of serum glycoprotein biomarkers for high grade serous ovarian cancer. Proteomics - Clinical Applications, 17 (4) 2200114, 1-16. doi: 10.1002/prca.202200114

Raninga, Prahlad V., He, Yaowu, Datta, Keshava K., Lu, Xue, Maheshwari, Uma R., Venkat, Pooja, Mayoh, Chelsea, Gowda, Harsha, Kalimutho, Murugan, Hooper, John D. and Khanna, Kum Kum (2023). Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma. Molecular Therapy, 31 (3) ARTN 212011, 729-743. doi: 10.1016/j.ymthe.2022.12.011

Lyons, Nicholas, Giri, Rabina, Begun, Jakob, Clark, David A, Proud, David, He, Yaowu, Hooper, John and Kryza, Thomas (2023). Reactive oxygen species as mediators of disease progression and therapeutic response in colorectal cancer. Antioxidants and Redox Signaling, 39 (1-3), 186-205. doi: 10.1089/ars.2022.0127

Zammit, Andrew P., Hooper, John D., Brown, Ian, Clark, David A. and Riddell, Andrew D. (2023). In comparison with polypectomy, colorectal resection is associated with improved survival for patients diagnosed with malignant polyps. Colorectal Disease, 25 (2), 261-271. doi: 10.1111/codi.16369

Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2023). Missing parameters in malignant polyp histology reports: can appropriate decisions be made?. Pathology, 55 (1), 58-63. doi: 10.1016/j.pathol.2022.06.007

Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2023). Malignant polyps in the COVID ‐19 era: a population‐based analysis. ANZ Journal of Surgery, 93 (4), 932-938. doi: 10.1111/ans.18253

Zammit, Andrew P., Panahi, Seyed E., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2023). Management of high and low risk malignant polyps – a population wide analysis. Colorectal Disease, 25 (1), 66-74. doi: 10.1111/codi.16328

Lu, Xue, He, Yaowu, Johnston, Rebecca L., Nanayakarra, Devathri, Sankarasubramanian, Sivanandhini, Lopez, J. Alejandro, Friedlander, Michael, Kalimutho, Murugan, Hooper, John D., Raninga, Prahlad V. and Khanna, Kum Kum (2022). CBL0137 impairs homologous recombination repair and sensitizes high-grade serous ovarian carcinoma to PARP inhibitors. Journal of Experimental and Clinical Cancer Research, 41 (1) 355, 1-17. doi: 10.1186/s13046-022-02570-4

Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2022). Timing of surveillance colonoscopy following malignant colorectal polypectomy in Queensland. ANZ Journal of Surgery, 93 (3), 606-611. doi: 10.1111/ans.18069

Khan, Tashbib, Lyons, Nicholas J., Gough, Madeline, Kwah, Kayden K.X., Cuda, Tahleesa J., Snell, Cameron E., Tse, Brian W., Sokolowski, Kamil A., Pearce, Lesley A., Adams, Timothy E., Rose, Stephen E., Puttick, Simon, Pajic, Marina, Adams, Mark N., He, Yaowu, Hooper, John D. and Kryza, Thomas (2022). CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy. Theranostics, 12 (16), 6915-6930. doi: 10.7150/thno.78171

Zammit, Andrew P., Brown, Ian, Hooper, John D., Clark, David A. and Riddell, Andrew D. (2022). A population‐based study of the management of rectal malignant polyps and the use of trans‐anal surgery. ANZ Journal of Surgery, 92 (11), 2949-2955. doi: 10.1111/ans.17917

Lee, Sui-Ting, Wong, Pooi-Fong, He, Hui, Hooper, John David and Mustafa, Mohd Rais (2022). Erratum: Alpha-Tomatine Attenuation of In Vivo Growth of Subcutaneous and Orthotopic Xenograft Tumors of Human Prostate Carcinoma PC-3 Cells Is Accompanied by Inactivation of Nuclear Factor-Kappa B Signaling (PLoS ONE (2013) 8:2 (e57708) DOI: 10.1371/journal.pone.0057708). PLoS ONE, 17 (5 May) e0268234. doi: 10.1371/journal.pone.0268234

Pagel, Charles N., Kularathna, Pamu K., Sanaei, Reza, Young, Neil D., Hooper, John D. and Mackie, Eleanor J. (2022). Protease‐activated receptor‐2 dependent and independent responses of bone cells to prostate cancer cell secretory products. The Prostate, 82 (6), 723-739. doi: 10.1002/pros.24316

Zammit, Andrew P., Lyons, Nicholas J., Chatfield, Mark D., Hooper, John D., Brown, Ian, Clark, David A. and Riddell, Andrew D. (2022). Patient and pathological predictors of management strategy for malignant polyps following polypectomy: a systematic review and meta-analysis. International Journal of Colorectal Disease, 37 (5), 1035-1047. doi: 10.1007/s00384-022-04142-6

Sanaei, R., Kularathna, P. K., Taghavi, N., Hooper, J. D., Pagel, C. N. and Mackie, E. J. (2021). Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: involvement of interleukin-6. Bone Reports, 15 101113, 101113. doi: 10.1016/j.bonr.2021.101113

Cuda, Tahleesa J., He, Yaowu, Kryza, Thomas, Khan, Tashbib, Tse, Brian W., Sokolowski, Kamil A., Liu, Cheng, Lyons, Nicholas, Gough, Madeline, Snell, Cameron E., Wyld, David K., Rose, Stephen, Riddell, Andrew D., Stevenson, Andrew R. L., Thomas, Paul A., Clark, David A., Puttick, Simon and Hooper, John D. (2021). Preclinical molecular PET-CT imaging targeting CDCP1 in colorectal cancer. Contrast Media and Molecular Imaging, 2021 3153278, 3153278. doi: 10.1155/2021/3153278

He, Yaowu, Khan, Tashbib, Kryza, Thomas, Jones, Martina L., Goh, Justin B., Lyons, Nicholas J., Pearce, Lesley A., Lee, Michael D, Gough, Madeline, Rogers, Rebecca, Davies, Claire M,, Gilks, C. Blake, Hodgkinson, Thomas, Lourie, Rohan, Barry, Sinead C., Perrin, Lewis C., Williams, Charlotte C., Puttick, Simon, Adams, Timothy E., Munro, Trent P., Hooper, John D. and Chetty, Naven (2021). Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer. Molecular Pharmaceutics, 18 (9) acs.molpharmaceut.1c00401, 3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401

Alharbi, Mona, Lai, Andrew, Sharma, Shayna, Kalita-De Croft, Priyakshi, Godbole, Nihar, Campos, America, Guanzon, Dominic, Salas-Burgos, Alexis, Carrion, Flavio, Zuñiga, Felipe A., Perrin, Lewis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Hooper, John D., Rice, Gregory E. and Salomon, Carlos (2021). Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence. Cancers, 13 (14) 3388, 1-26. doi: 10.3390/cancers13143388

Kryza, Thomas, Khan, Tashbib, Lovell, Scott, Harrington, Brittney S., Yin, Julia, Porazinski, Sean, Pajic, Marina, Koistinen, Hannu, Rantala, Juha K., Dreyer, Tobias, Magdolen, Viktor, Reuning, Ute, He, Yaowu, Tate, Edward W. and Hooper, John D. (2021). Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1. Nature Chemical Biology, 17 (7), 776-783. doi: 10.1038/s41589-021-00783-w

Khan, Tashbib, Kryza, Thomas, Lyons, Nicholas J., He, Yaowu and Hooper, John D. (2021). The CDCP1 signalling hub: a target for cancer detection and therapeutic intervention. Cancer Research, 81 (9) canres.2978.2020, QF1-QF11. doi: 10.1158/0008-5472.can-20-2978

Ramarao-Milne, Priya, Kondrashova, Olga, Barry, Sinead, Hooper, John D., Lee, Jason S. and Waddell, Nicola (2021). Histone modifying enzymes in gynaecological cancers. Cancers, 13 (4) 816, 1-21. doi: 10.3390/cancers13040816

Sheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012

Cuda, Tahleesa J., Riddell, Andrew D., Liu, Cheng, Whitehall, Vicki L., Borowsky, Jennifer, Wyld, David K., Burge, Matthew E., Ahern, Elizabeth, Griffin, Alison, Lyons, Nicholas J. R., Rose, Stephen E., Clark, David A., Stevenson, Andrew R. L., Hooper, John D., Puttick, Simon and Thomas, Paul A. (2020). PET imaging quantifying Ga-PSMA-11 uptake in metastatic colorectal cancer. The Journal of Nuclear Medicine, 61 (11), 1576-1579. doi: 10.2967/jnumed.119.233312

Khan, Tashbib, Sullivan, Mitchell A., Gunter, Jennifer H., Kryza, Thomas, Lyons, Nicholas, He, Yaowu and Hooper, John D. (2020). Revisiting Glycogen in Cancer: A Conspicuous and Targetable Enabler of Malignant Transformation. Frontiers in Oncology, 10 592455, 592455. doi: 10.3389/fonc.2020.592455

Jia, Liyang, Gao, Yanan, He, Yaowu, Hooper, John D. and Yang, Pengyuan (2020). HBV induced hepatocellular carcinoma and related potential immunotherapy. Pharmacological Research, 159 104992, 104992. doi: 10.1016/j.phrs.2020.104992

Alharbi, Mona, Sharma, Shayna, Guanzon, Dominic, Lai, Andrew, Zuñiga, Felipe, Shiddiky, Muhammad J.A., Yamauchi, Yusuke, Salas-Burgos, Alexis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2020). miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 28 102207, 102207. doi: 10.1016/j.nano.2020.102207

Harrington, Brittney S., He, Yaowu, Khan, Tashbib, Puttick, Simon, Conroy, Paul J., Kryza, Thomas, Cuda, Tahleesa, Sokolowski, Kamil A., Tse, Brian W.C ., Robbins, Katherine K., Arachchige, Buddhika J., Stehbens, Samantha J., Pollock, Pamela M., Reed, Sarah, Weroha, S. John, Haluska, Paul, Salomon, Carlos, Lourie, Rohan, Perrin, Lewis C., Law, Ruby H. P., Whisstock, James C. and Hooper, John D. (2020). Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer. Theranostics, 10 (5), 2095-2114. doi: 10.7150/thno.30736

Kryza, Thomas, Khan, Tashbib, Puttick, Simon, Li, Chao, Sokolowski, Kamil A., Tse, Brian W.C., Cuda, Tahleesa, Lyons, Nicholas, Gough, Madeline, Yin, Julia, Parkin, Ashleigh, Deryugina, Elena I., Quigley, James P., Law, Ruby H.P., Whisstock, James C., Riddell, Andrew D., Barbour, Andrew P., Wyld, David K., Thomas, Paul A., Rose, Stephen, Snell, Cameron E., Pajic, Marina, He, Yaowu and Hooper, John D. (2020). Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma. Theranostics, 10 (9), 4116-4133. doi: 10.7150/thno.43589

Kryza, Thomas, Bock, Nathalie, Lovell, Scott, Rockstroh, Anja, Lehman, Melanie L., Lesner, Adam, Panchadsaram, Janaththani, Silva, Lakmali Munasinghage, Srinivasan, Srilakshmi, Snell, Cameron E., Williams, Elizabeth D., Fazli, Ladan, Gleave, Martin, Batra, Jyotsna, Nelson, Colleen, Tate, Edward W., Harris, Jonathan, Hooper, John D. and Clements, Judith A. (2019). The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer. Molecular Oncology, 14 (1) 1878-0261.12587, 105-128. doi: 10.1002/1878-0261.12587

He, Yaowu, Davies, Claire M., Harrington, Brittney S., Hellmers, Linh, Sheng, Yonghua, Broomfield, Amy, McGann, Thomas, Bastick, Kate, Zhong, Laurie, Wu, Andy, Maresh, Grace, McChesney, Shannon, Yau Wong, Kuan, Adams, Mark N., Sullivan, Ryan C., Palmer, James S., Burke, Lez J., Ewing, Adam D., Zhang, Xin, Margolin, David, Li, Li, Lourie, Rohan, Matsika, Admire, Srinivasan, Bhuvana, McGuckin, Michael A., Lumley, John W. and Hooper, John D. (2019). CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin. Oncogene, 39 (1), 219-233. doi: 10.1038/s41388-019-0983-3

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Palma, Carlos, Zuñiga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D and Salomon, Carlos (2019). Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells. Clinical Science, 133 (13), CS20190082-1419. doi: 10.1042/cs20190082

Alharbi, Mona, Zuñiga, Felipe, Elfeky, Omar, Guanzon, Dominic, Lai, Andrew, Rice, Gregory E., Perrin, Lewis, Hooper, John and Salomon, Carlos (2018). The potential role of miRNAs and exosomes in chemotherapy in ovarian cancer. Endocrine-Related Cancer, 25 (12), R663-R685. doi: 10.1530/erc-18-0019

Sharma, Shayna, Alharbi, Mona, Kobayashi, Miharu, Lai, Andrew, Guanzon, Dominic, Zuñiga, Felipe, Ormazabal, Valeska, Palma, Carlos, Scholz-Romero, Katherin, Rice, Gregory E., Hooper, John D. and Salomon, Carlos (2018). Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migration. Clinical Science, 132 (18), 2029-2044. doi: 10.1042/CS20180425

He, Yaowu, Reid, Janet C., He, Hui, Harrington, Brittney S., Finlayson, Brittney, Khan, Tashbib and Hooper, John D. (2018). Evidence that cell surface localization of serine protease activity facilitates cleavage of the protease activated receptor CDCP1. Biological Chemistry, 399 (9), 1091-1097. doi: 10.1515/hsz-2017-0308

Nguyen, Thu H. M., Carreira, Patricia E., Sanchez-Luque, Francisco J., Schauer, Stephanie N., Fagg, Allister C., Richardson, Sandra R., Davies, Claire M., Jesuadian, J. Samuel, Kempen, Marie-Jeanne H. C., Troskie, Robin-Lee, James, Cini, Beaven, Elizabeth A., Wallis, Tristan P., Coward, Jermaine I. G., Chetty, Naven P., Crandon, Alexander J., Venter, Deon J., Armes, Jane E., Perrin, Lewis C., Hooper, John D., Ewing, Adam D., Upton, Kyle R. and Faulkner, Geoffrey J. (2018). L1 retrotransposon heterogeneity in ovarian tumor cell evolution. Cell Reports, 23 (13), 3730-3740. doi: 10.1016/j.celrep.2018.05.090

Sharma, Shayna, Zuñiga, Felipe, Rice, Gregory E., Perrin, Lewis C., Hooper, John D. and Salomon, Carlos (2017). Tumor-derived exosomes in ovarian cancer - liquid biopsies for early detection and real-time monitoring of cancer progression. Oncotarget, 8 (61), 104687-104703. doi: 10.18632/oncotarget.22191

Kryza, Thomas, Silva, Lakmali M., Bock, Nathalie, Fuhrman-Luck, Ruth, Stephens, Carson, Gao, Jin, Samaratunga, Hema, Lawrence, Mitchell, Hooper, John D., Dong, Ying, Risbridger, Gail and Clements, Judith A. (2017). Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells. Molecular Oncology, 11 (10), 1307-1329. doi: 10.1002/1878-0261.12075

Sullivan, Ryan, Maresh, Grace, Zhang, Xin, Salomon, Carlos, Hooper, John, Margolin, David and Li, Li (2017). The emerging roles of extracellular vesicles as communication vehicles within the tumor microenvironment and beyond. Frontiers in Endocrinology, 8 (AUG) 194, 194. doi: 10.3389/fendo.2017.00194

Zhao, Shuo, Dorn, Julia, Napieralski, Rudolf, Walch, Axel, Diersch, Sandra, Kotzsch, Matthias, Ahmed, Nancy, Hooper, John D., Kiechle, Marion, Schmitt, Manfred and Magdolen, Viktor (2017). Plasmin(ogen) serves as a favorable biomarker for prediction of survival in advanced high-grade serous ovarian cancer. Biological Chemistry, 398 (7), 765-773. doi: 10.1515/hsz-2016-0282

Adams, Mark N., Burgess, Joshua T., He, Yaowu, Gately, Kathy, Snell, Cameron, Zhang, Shu-Dong, Hooper, John D., Richard, Derek J. and O'Byrne, Kenneth J. (2017). Expression of CDCA3 is a prognostic biomarker and potential therapeutic target in non–small cell lung cancer. Journal of Thoracic Oncology, 12 (7), 1071-1084. doi: 10.1016/j.jtho.2017.04.018

Chen, Yang, Harrington, Brittney S., Lau, Kevin C. N., Burke, Lez J., He, Yaowu, Iconomou, Mary, Palmer, James S., Meade, Brian, Lumley, John W. and Hooper, John D. (2017). Development of an enzyme-linked immunosorbent assay for detection of CDCP1 shed from the cell surface and present in colorectal cancer serum specimens. Journal of Pharmaceutical and Biomedical Analysis, 139, 65-72. doi: 10.1016/j.jpba.2017.02.047

Suen, J.Y., Adams, M. N., Lim, J., Madala, P.K., Xu, W, Cotterell, A., He, Y., Yua, Mei-Kwan, Hooper, J. D. and Fairlie, D.P. (2017). Mapping transmembrane residues of proteinase activated recpetor 2 (PAR2) that influence ligand-modulated calcium signaling. Pharmacological Research, 117, 328-342. doi: 10.1016/j.phrs.2016.12.020

Sheng, Yonghua, Ng, Choa Ping, Lourie, Rohan, Shah, Esha T., He, Yaowu, Wong, Kuan Yua, Seim, Inge, Oancea, Iulia, Morais, Christudas, Jeffery, Penny L., Hooper, John, Gobe, Glenda C. and Mcguckin, Michael A. (2017). MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance. International Journal of Cancer, 140 (10), 2351-2363. doi: 10.1002/ijc.30651

Lassemillante, Annie-Claude M., Skinner, Tina L., Hooper, John D., Prins, John B. and Wright, Olivia R. L. (2017). Osteoporosis-Related Health Behaviors in Men With Prostate Cancer and Survivors Exploring Osteoporosis Knowledge, Health Beliefs, and Self-Efficacy. American Journal of Men’s Health, 11 (1), 13-23. doi: 10.1177/1557988315615956

Reid, Janet C., Matsika, Admire, Davies, Claire M., He, Yaowu, Broomfield, Amy, Bennett, Nigel C., Magdolen, Viktor, Srinivasan, Bhuvana, Clements, Judith A. and Hooper, John D. (2017). Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases. American Journal of Cancer Research, 7 (11), 2257-2274.

Reid, Janet C., Bennett, Nigel C., Stephens, Carson R., Carroll, Melanie L., Magdolen, Viktor, Clements, Judith A. and Hooper, John D. (2016). In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B. Biological Chemistry, 397 (12), 1299-1305. doi: 10.1515/hsz-2016-0163

Sheng, Y. H., He, Y., Hasnain, S. Z., Wang, R., Tong, H., Clarke, D. T., Lourie, R., Oancea, I., Wong, K. Y., Lumley, J. W., Florin, T. H., Sutton, P., Hooper, J. D., McMillan, N. A. and McGuckin, M. A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target. Oncogene, 36 (5), 700-713. doi: 10.1038/onc.2016.241

Wu, Andy C., He, Yaowu, Broomfield, Amy, Paatan, Nicoll J., Harrington, Brittney S., Tseng, Hsu-Wen, Beaven, Elizabeth A., Kiernan, Deirdre M., Swindle, Peter, Clubb, Adrian B., Levesque, Jean-Pierre, Winkler, Ingrid G., Ling, Ming-Tat, Srinivasan, Bhuvana, Hooper, John D. and Pettit, Allison R. (2016). CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer. Journal of Pathology, 239 (2), 218-230. doi: 10.1002/path.4718

Harrington, Brittney S., He, Yaowu, Davies, Claire M., Wallace, Sarah J., Adams, Mark N., Beaven, Elizabeth A., Roche, Deborah K., Kennedy, Catherine, Chetty, Naven P., Crandon, Alexander J., Flatley, Christopher, Oliveira, Niara B., Shannon, Catherine M., deFazio, Anna, Tinker, Anna V., Gilks, C. Blake, Gabrielli, Brian, Brennan, Donal J., Coward, Jermaine I., Armes, Jane E., Perrin, Lewis C. and Hooper, John D. (2016). Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer. British Journal of Cancer, 114 (4), 417-426. doi: 10.1038/bjc.2015.471

He, Yaowu, Harrington, Brittney S. and Hooper, John D. (2016). New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways. Oncoscience, 3 (1), 5-8. doi: 10.18632/oncoscience.286

Yau, Mei-Kwan, Suen, Jacky Y., Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark N., He, Yaowu, Hooper, John D., Reid, Robert C. and Fairlie, David P. (2016). Potent small agonists of protease activated receptor 2. ACS Medicinal Chemistry Letters, 7 (1), 105-110. doi: 10.1021/acsmedchemlett.5b00429

Matsika, Admire, Srinivasan, Bhuvana, Day, Christopher, Mader, Sabina Ann, Kiernan, Deirdre Margaret, Broomfield, Amy, Fu, Jinlin, Hooper, John D., Kench, James G. and Samaratunga, Hemamali (2015). Cancer stem cell markers in prostate cancer: An immunohistochemical study of ALDH1, SOX2 and EZH2. Pathology, 47 (7), 622-628. doi: 10.1097/PAT.0000000000000325

Holzapfel, Boris M., Hutmacher, Dietmar W., Nowlan, Bianca, Barbier, Valerie, Thibaudeau, Laure, Theodoropoulos, Christina, Hooper, John D., Loessner, Daniela, Clements, Judith A., Russell, Pamela J., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2015). Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials, 61, 103-114. doi: 10.1016/j.biomaterials.2015.04.057

McDonald, Cameron J., Ostini, Lesa, Bennett, Nigel, Subramaniam, Nanthakumar, Hooper, John, Velasco, Gloria, Wallace, Daniel F. and Nathan Subramaniam, V. (2015). Functional analysis of matriptase-2 mutations and domains: Insights into the molecular basis of iron-refractory iron deficiency anemia. American Journal of Physiology - Cell Physiology, 308 (7), C539-C547. doi: 10.1152/ajpcell.00264.2014

Wallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225

Lassemillante, Annie-Claude M., Doi, Suhail A. R., Hooper, John D., Prins, John B. and Wright, Olivia R. L. (2015). Prevalence of osteoporosis in prostate cancer survivors II: a meta-analysis of men not on androgen deprivation therapy. Endocrine, 50 (2), 344-354. doi: 10.1007/s12020-015-0536-7

Adams, M. N., Harrington, B. S., He, Y., Davies, C. M., Wallace, S. J., Chetty, N. P., Crandon, A. J., Oliveira, N. B., Shannon, C. M., Coward, J. I., Lumley, J. W., Perrin, L. C., Armes, J. E. and Hooper, J. D. (2015). EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface. Oncogene, 34 (11), 1375-1383. doi: 10.1038/onc.2014.88

Dong, Ying, Harrington, Brittney S., Adams, Mark N., Wortmann, Andreas, Stephenson, Sally-Anne, Lisle, Jessica, Herington, Adrian, Hooper, John D. and Clements, Judith A. (2014). Activation of membrane-bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases. Biological Chemistry, 395 (9), 977-990. doi: 10.1515/hsz-2014-0147

Lassemillante, Annie-Claude M., Doi, Suhail A. R, Hooper, John D., Prins, John B. and Wright, Olivia R. L. (2014). Prevalence of osteoporosis in prostate cancer survivors: a meta-analysis. Endocrine, 45 (3), 370-381. doi: 10.1007/s12020-013-0083-z

Bennett, Nigel C., Hooper, John D., Johnson, David W. and Gobe, Glenda C. (2014). Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines. Prostate, 74 (5), 478-487. doi: 10.1002/pros.22767

Lee, Sui-Ting, Wong, Pooi-Fong, Hooper, John David and Mustafa, Mohd Rais (2013). Alpha-tomatine synergises with paclitaxel to enhance apoptosis of androgen-independent human prostate cancer PC-3 cells in vitro and in vivo. Phytomedicine, 20 (14), 1297-1305. doi: 10.1016/j.phymed.2013.07.002

Lee, Sui-Ting, Wong, Pooi-Fong, He, Hui, Hooper, John David and Mustafa, Mohd Rais (2013). Alpha-Tomatine Attenuation of In Vivo Growth of Subcutaneous and Orthotopic Xenograft Tumors of Human Prostate Carcinoma PC-3 Cells Is Accompanied by Inactivation of Nuclear Factor-Kappa B Signaling. PLoS One, 8 (2), e57708-e57708. doi: 10.1371/journal.pone.0057708

McGovern, J. A., Heinemann, J. R., Burke, L. J., Dawson, R., Parker, T. J., Upton, Z., Hooper, J. D. and Manton, K. J. (2013). Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration. British Journal of Dermatology, 168 (3), 496-503. doi: 10.1111/bjd.12119

Bennett, Nigel C., Hooper, John D., Lambie, Duncan, Lee, Cheok S., Yang, Tao, Vesey, David A., Samaratunga, Hemamali, Johnson, David W. and Gobe, Glenda C. (2012). Evidence for steroidogenic potential in human prostate cell lines and tissues. American Journal of Pathology, 181 (3), 1078-1087. doi: 10.1016/j.ajpath.2012.06.009

Casar, B., He, Y., Iconomou, M., Hooper, J. D., Quigley, J. P. and Deryugina, E. I. (2012). Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells. Oncogene, 31 (35), 3924-3938. doi: 10.1038/onc.2011.555

Sanchez, Washington Y., de Veer, Simon J., Swedberg, Joakim E., Hong, Eui-Ju, Reid, Janet C., Walsh, Terry P., Hooper, John D., Hammond, Geoffrey L., Clements, Judith A. and Harris, Jonathan M. (2012). Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells. Endocrinology, 153 (7), 3179-3189. doi: 10.1210/en.2012-1011

Dong, Ying, He, Yaowu, de Boer, Leonore, Stack, M. Sharon, Lumley, John W., Clements, Judith A. and Hooper, John D. (2012). The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration. Journal of Biological Chemistry, 287 (13), 9792-9803. doi: 10.1074/jbc.M111.335448

Adams, Mark N., Pagel, Charles N., Mackie, Eleanor J. and Hooper, John D. (2012). Evaluation of antibodies directed against human protease-activated receptor-2. Naunyn-Schmiedeberg's Archives of Pharmacology, 385 (9), 861-873. doi: 10.1007/s00210-012-0783-6

Wortmann, Andreas, He, Yaowu, Christensen, Melinda E., Linn, Mayla, Lumley, John W., Pollock, Pamela M., Waterhouse, Nigel J. and Hooper, John D. (2011). Cellular settings mediating Src substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734. Journal of Biological Chemistry, 206 (49), 42303-42315. doi: 10.1074/jbc.M111.227462

Adams, Mark N., Christensen, Melinda E., He, Yaowu, Waterhouse, Nigel J. and Hooper, John D. (2011). The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2. PLoS One, 6 (11) e28018, 1-14. doi: 10.1371/journal.pone.0028018

Adams, Mark N., Ramachandran, Rithwik, Yau, Mei-Kwan, Suen, Jacky Y., Fairlie, David P., Hollenberg, Morley D. and Hooper, John D. (2011). Structure, function and pathophysiology of protease activated receptors. Pharmacology and Therapeutics, 120 (3), 248-282. doi: 10.1016/j.pharmthera.2011.01.003

He, Yaowu, Wortmann, Andreas, Burke, Les J., Reid, Janet C., Adams, Mark N., Abdul-Jabbar, Ibtissam, Quigley, James P., Leduc, Richard, Kirchhofer, Daniel and Hooper, John D. (2010). Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKC delta. Journal of Biological Chemistry, 285 (34), 26162-26173. doi: 10.1074/jbc.M109.096453

Antalis, Toni M., Buzza, Marguerite S., Hodge, Kathryn M., Hooper, John D. and Netzel-Arnett, Sarah (2010). The cutting edge: Membrane-anchored serine protease activities in the pericellular microenvironment. Biochemical Journal, 428 (3), 325-346. doi: 10.1042/BJ20100046

Bennett, Nigel C., Gardiner, Robert A., Hooper, John D., Johnson, David W. and Gobe, Glenda C. (2010). Molecular cell biology of androgen receptor signalling. International Journal of Biochemistry and Cell Biology, 42 (6), 813-827. doi: 10.1016/j.biocel.2009.11.013

Bennett, Nigel, Hooper, John D., Lee, C. Soon and Gobe, Glenda C. (2009). Androgen Receptor and Caveolin-1 in Prostate Cancer. IUBMB Life, 61 (10), 961-970. doi: 10.1002/IUB.244

Sarah Netzel-Arnett, Thomas H. Bugge, Rex A. Hess, Kay Carnes, Brett W. Stringer, Anthony L. Scarman, John D. Hooper, Ian D. Tonks, Graham F. Kay and Toni M. Antalis (2009). The Glycosylphosphatidylinositol-Anchored Serine Protease PRSS21 (Testisin) Imparts Murine Epididymal Sperm Cell Maturation and Fertilizing Ability. Biology of Reproduction, 81 (5), 921-932. doi: 10.1095/biolreprod.109.076273

Swedberg, Joakim E., Nigon, Laura V., Reid, Janet C., de Veer, Simon J., Walpole, Carina M., Stephens, Carson R., Walsh, Terry P., Takayama, Thomas K., Hooper, John D., Clements, Judith A., Buckle, Ashley M. and Harris, Jonathan M. (2009). Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4. Chemistry and Biology, 16 (6), 633-643. doi: 10.1016/j.chembiol.2009.05.008

Ramsay, Andrew J., Hooper, John D., Folgueras, Alicia R., Velasco, Gloria and Lopez-Otin, Carlos (2009). Matriptase-2 (TMPRSS6): A proteolytic regulator of iron homeostasis. Haematologica, 94 (6), 840-849. doi: 10.3324/haematol.2008.001867

Deryugina, Elena I., Conn, Erin M., Wortmann, Andreas, Partridge, Juneth J., Kupriyanova, Tatyana A., Ardi, Veronica C., Hooper, John D. and Quigley, James P. (2009). Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. Molecular Cancer Research, 7 (8), 1197-1211. doi: 10.1158/1541-7786.MCR-09-0100

Wortmann, Andreas, He, Yaowu, Deryugina, Elena I., Quigley, James P. and Hooper, John D. (2009). The cell surface glycoprotein CDCP1 in cancer - Insights, opportunities, and challenges. IUBMB Life, 61 (7), 723-730. doi: 10.1002/iub.198

He, Yaowu, Hryciw, Deanne H., Carroll, Melanie L., Myers, Stephen A., Whitbread, Astrid K., Kumar, Sharad, Poronnik, Philip and Hooper, John D. (2008). The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. Journal of Biological Chemistry, 283 (35), 24000-24010. doi: 10.1074/jbc.M803361200

He, Yaowu, Ramsay, Andrew, Hunt, Melanie, Whitbread, Astrid, Myers, Stephen and Hooper, John (2008). N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2). Biochemical Journal, 412 (1), 45-55. doi: 10.1042/BJ20071722

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A. and Hooper, John D. (2008). Kallikrein-related peptidase 4( KLK4)initiates intracellular signaling via protease-activated receptors(PARs):KLK4 and PAR-2 are co-expressed during prostate cancer progression. The Journal of Biological Chemistry, 283 (18), 12293-12304. doi: 10.1074/jbc.M709493200

Myers, Stephen A., Kaushal, Aneel, Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., Hunt, Melanie L., Digby, Matthew R., Samaratunga, Hemamali, Gardiner, Robert A., Clements, Judith A. and Hooper, John D. (2008). A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus. Prostate, 68 (4), 381-399. doi: 10.1002/pros.20685

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D. and Clements, Judith A. (2008). Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function. Biological Chemistry, 389 (2), 99-109. doi: 10.1515/BC.2008.013

Ramsay, Andrew J., Reid, Janet C., Velasco, Gloria, Quigley, James P. and Hooper, John D. (2008). The type II transmembrane serine protease Matriptase-2 - identification, structural features, enzymology, expression pattern and potential roles. Frontiers in Bioscience, 13 (2), 569-579. doi: 10.2741/2702

Vesey, David A., Hooper, John D., Gobe, Glenda C. and Johnson, David W. (2007). Potential physiological and pathophysiological roles for protease-activated receptor-2 in the kidney. Nephrology, 12 (1), 36-43. doi: 10.1111/j.1440-1797.2006.00746.x

Wilson, S, Greer, B, Hooper, J, Zijlstra, A, Walker, B, Quigley, J and Hawthorne, S (2005). The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells. Biochemical Journal, 388 (3), 967-972. doi: 10.1042/BJ20041066

Hooper, John D., Campagnolo, Luisa, Goodarzi, Goodarz, Truong, Tony N., Stuhlmann, Heidi and Quigley, James P. (2003). Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues. Biochemical Journal, 373 (3), 689-702. doi: 10.1042/BJ20030390

Netzel-Arnett, Sarah, Hooper, John D., Szabo, Roman, Madison, Edwin L., Quigley, James P., Bugge, Thomas H. and Antalis, Toni M. (2003). Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer and Metastasis Reviews, 22 (2-3), 237-258. doi: 10.1023/A:1023003616848

Hooper, John D., Zijlstra, Andries, Aimes, Ronald T., Liang, Hongyan, Claassen, Gisela F., Tarin, David, Testa, Jacqueline E. and Quigley, James P. (2003). Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene, 22 (12), 1783-1794. doi: 10.1038/sj.onc.1206220

Aimes, RT, Zijlstra, A, Hooper, JD, Ogbourne, SM, Sit, ML, Fuchs, S, Gotley, DC, Quigley, JP and Antalis, TM (2003). Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis. Thrombosis And Haemostasis, 89 (3), 561-572. doi: 10.1055/s-0037-1613388

Zijlstra, A, Mellor, R, Panzarella, G, Aimes, RT, Hooper, JD, Marchenko, ND and Quigley, JP (2002). A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction. Cancer Research, 62 (23), 7083-7092.

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L. and Clements, Judith A. (2001). TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma. Genomics, 77 (3), 200-207. doi: 10.1006/geno.2001.6629

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K. and Clements, Judith A. (2001). Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle. Genomics, 73 (1), 117-122. doi: 10.1006/geno.2000.6490

Scarman, Anthony L., Hooper, John D., Boucaut, Kerry J., Sit, Mae-Le, Webb, Graham C., Normyle, John F. and Antalis, Toni M. (2001). Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis. European Journal of Biochemistry, 268 (5), 1250-1258. doi: 10.1046/j.1432-1327.2001.01986.x

Hooper, John D., Clements, Judith A., Quigley, James P. and Antalis, Toni M. (2001). Type II transmembrane serine proteases - Insights into an emerging class of cell surface proteolytic enzymes. Journal of Biological Chemistry, 276 (2), 857-860. doi: 10.1074/jbc.R000020200

Clements, Judith, Hooper, John, Dong, Ying and Harvey, Tracey (2001). The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential function.. Biological Chemistry, 382 (1), 5-14. doi: 10.1515/BC.2001.002

Harvey, TJ, Hooper, JD, Myers, SA, Stephenson, SA, Ashworth, LK and Clements, JA (2000). Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4. Journal of Biological Chemistry, 275 (48), 37397-37406. doi: 10.1074/jbc.M004525200

Hooper, John D., Baker, Elizabeth, Ogbourne, Steven M., Sutherland, Grant R. and Antalis, Toni M. (2000). Cloning of the cDNA and localization of the gene encoding human NRBP, a ubiquitously expressed, multidomain putative adapter protein. Genomics, 66 (1), 113-118. doi: 10.1006/geno.2000.6167

Hooper, J. D., Scarman, A. L., Clarke, B., Normyle, J. F. and Antalis, T. M. (2000). Localization of the mosaic transmembrane serine protease corin to heart myocytes. European Journal of Biochemistry, 267 (23), 6931-6937. doi: 10.1046/j.1432-1327.2000.01806.x

Hooper, John D., Bowen, Natalie, Marshall, Heidi, Cullen, Lara M., Sood, Raman, Daniels, Rachael, Stuttgen, Melanie A., Normyle, John F., Higgs, Douglas R., Kastner, Daniel L., Ogbourne, Steven M., Pera, Martin F., Jazwinska, Elizabeth C. and Antalis, Toni M. (2000). Localization, expression and genomic structure of the gene encoding the human serine protease testisin. Biochimica et Biophysica Acta, 1492 (1), 63-71. doi: 10.1016/S0167-4781(00)00071-3

Hooper, J. D., Nicol, D. L., Dickinson, J. L., Eyre, H. J., Scarman, A. L., Normyle, J. F., Stuttgen, M. A., Douglas, M. L., Loveland, K. A. L., Sutherland, G. R. and Antalis, T. M. (1999). Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors. Cancer Research, 59 (13), 3199-3205.

McGahan, William, Gough, Madeleine, Liu, Cheng, Cavallucci, David, Thomas, Paul and Hooper, John (2024). O47 FAP expression transforms early in the tumorigenesis of pancreatic ductal adenocarcinoma; and can be detected on FAPI-PET/CT. BSG LIVE'24, Birmingham, United Kingdom, 17-20 June 2024. London, United Kingdom: BMJ Group. doi: 10.1136/gutjnl-2024-bsg.47

Godbole, Nihar, Ravichandran, Akhilandeshwari, Guanzon, Dominic, Lai, Andrew, Carrion, Flavio, de Croft, Priyakshi Kalita, Perrin, Lewis, Hooper, John, Bray, Laura and Salomon, Carlos (2024). Changes in extracellular vesicle miRNAs from three-dimensional ovarian cancer cell models reflect physiological changes and cancer survival. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-3386

Kwah, Kayden, Gu, Weixi, Arachchige, Kasun S. A., He, Yaowu, Landsberg, Michael, Kobe, Bostjan and Hooper, John (2023). Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323084449

Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron Edward (2023). HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult cases. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.e13561

Gough, Madeline, Kwah, Kayden, He, Yaowu, Snell, Cameron Edward, Hooper, John D. and Kryza, Thomas (2023). Development of a CUB domain-containing protein 1 (CDCP1)-targeting antibody-drug conjugate for triple-negative and metastatic breast cancer. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 02-06, 2023. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Gough, Madeline, Kwah, Kayden, He, Yaowu, Snell, Cameron Edward, Hooper, John D. and Kryza, Thomas (2023). Development of a CUB domain-containing protein 1 (CDCP1)-targeting antibody-drug conjugate for triple-negative and metastatic breast cancer. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology (ASCO). doi: 10.1200/jco.2023.41.16_suppl.e15012

Gough, Madeline, Khan, Tashbib, Kwah, Kayden, He, Yaowu, Ratnayake, Gishan, Pyke, Christopher, Snell, Cameron, Hooper, John and Kryza, Thomas (2023). Abstract P4-07-26: Development of CDCP1-targeting antibody-drug conjugate for Triple negative and metastatic breast cancer. 2022 San Antonio Breast Cancer Symposium, San Antonio, TX United States, 6-10 December 2022. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.sabcs22-p4-07-26

Gough, M., Kwah, K., Khan, T., He, Y., Pyke, C., Ratnayake, G., Snell, C., Hooper, J. and Kryza, T. (2022). Development of antibody-drug conjugates targeting the CDCP1 receptor for the treatment of Triple negative and metastatic breast cancer. 13th European Breast Cancer Conference (EBCC-13), Barcelona, Spain, 16-18 November 2022. Oxford, United Kingdom: Elsevier. doi: 10.1016/s0959-8049(22)01571-4

Lyons, Nicholas, Hooper, John, Clark, David, Riddell, Andrew and Kryza, Thomas (2022). Intraoperative identification of colorectal cancer lesions using indocyanine green labelled antibodies in preclinical murine models. Association of Surgeons of Great Britain and Ireland, Annual Congress, Liverpool, United Kingdom, 3-5 May 2022. Oxford, United Kingdom: Oxford University Press . doi: 10.1093/bjs/znac245.093

Lyons, Nicholas, Hooper, John, Kryza, Thomas, Clark, David and Riddell, Andrew (2022). EP-369 examining EphA2 expression in colorectal cancer. Association of Surgeons of Great Britain and Ireland Annual Congress, Liverpool, United Kingdom, 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/bjs/znac245.094

Sheng, Yong H., Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh Y., He, Yaowu, Wu, Andy, Hooper, John, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira Z., McGuckin, Michael, Florin, Timothy H. and Begun, Jakob (2020). Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy. DDW 2020, Online, 2-5 May 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)30856-8

Andrews, Ariel, Kumar, Ramyashree Prasanna, Nazareth, Deborah, Ehmann, Anna, Hooper, John, McMillan, Nigel and Gabrielli, Brian (2019). Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, MA USA, 26-30 October 2019. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/1535-7163.TARG-19-A060

Cuda, T., Thomas, P., Rose, S., Puttick, S. and Hooper, J. (2019). "Theranostics" - radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer in preclinical cancer models. 32nd Annual Congress of the European-Association-of-Nuclear-Medicine (EANM), Barcelona, Spain, 12-16 October 2019. Heidelberg, Germany: Springer.

Cuda, T., Riddell, A., Thomas, P., Puttick, S. and Hooper, J. (2019). GALIUM-68-PSMA-617 AS A NOVEL PET-CT MARKER FOR DISEASE STRATIFYING METASTATIC COLORECTAL CANCER: A PROSPECTIVE PILOT STUDY. HOBOKEN: WILEY.

Cuda, T., Hooper, J., Puttick, S., He, Y., Kryza, T. and Khan, T. (2019). "Theranostics": radioimmunodetection and radioimmunotherapy for metastatic colorectal cancer. Australian and New Zealand Society of Nuclear Medicine (ANZSNM) 49th ASM, Adelaide, Australia, 26-28 April 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Alharbi, Mona G., Lai, Andrew, Zuniga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D. and Salomon, Carlos (2019). Ovarian cancer cell invasiveness regulates their exosomes which induces oncogenic potential and cancer progression in vivo. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, March 12-16, 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079

Sharma, Shayna, Lai, Andrew, Guanzon, Dominic, Morgan, Terry, Perrin, Lewis C., Hooper, John D. and Salomon, Carlos (2019). Circulating exosomal miRNAs from women with ovarian cancer for early detection and real-time monitoring of disease progression. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719119834079

Millard, Susan, Wu, Andy, Kaur, Simran, He, Yaowu, Batoon, Lena, Hooper, John and Pettit, Allison (2018). Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation. Annual Meeting of the American Society for Bone and Mineral Research, Montréal, Quebéc, Canada, Sep 28-Oct 01, 2018. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1002/jbmr.3621

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Sharma, Shayna, Palma, Carlos, Zuniga, Felipe, Rice, Gregory E., Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2018). Integrative Analysis of Multi-Omics Exosomal Data for Identifying Multi-Markers for Susceptibility to Chemotherapy in Ovarian Cancer. 65th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), San Diego Ca United States, 6-10 March 2018. Thousand Oaks, CA United States: Sage.

Sharma, Shayna, Scholz-Romero, Katherin, Kline, Richard, Wade, Katrina, Estes, Jacob, Palma, Carlos, Guanzon, Dominic, Lai, Andrew, Hooper, John, Rice, Gregory E. and Salomon, Carlos (2017). Exosomal content in the plasma of patients with ovarian cancer reflect tumor state and induce the epithelial to mesenchymal transition in target cells. 64th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Orlando, FL, United States, 15-18 March 2017. Thousand Oaks, CA, United States: Sage Publications. doi: 10.1177/1933719117699773

Alharbi, Mona, Kline, Richard, Wade, Katrina, Estes, Jacob, Hooper, John, Rice, Gregory E. and Salomon, Carlos (2017). Ovarian cancer cells transfer resistance to chemotherapy to other cells via exosomes. 64th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Orlando, FL, United States, 5-18 March 2017. Heidelberg, Germany: Springer.

Sheng, Yong H., He, Yaowu, Hasnain, Sumaira Z., Wang, Ran, Tong, Hui, Clarke, Daniel T., Lourie, Rohan, Oancea, Lulia, Wong, Kuanyau, Lumley, John W., Florin, Timothy H., Sutton, Philip, Hooper, John. D., Mcmillan, Nigel A. and Mcguckin, Michael A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, Los Angeles, 16-20 April 2016 . Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3564

Kemp, M. C., Pummer, J., He, Y., Hooper, J., Reuter, B., Borgovan, T., Zhang, X., Sullivan, R., Maresh, G., Green, H., Del Valle, L., Margolin, D. and Li, L. (2016). The role of cancer stem cells in colorectal cancer metastasis. Southern Regional Meeting of the American Federation for Medical Research (AFMR), New Orleans, LA, United States, Feb 18-20, 2016. London, United Kingdom: BMJ Group. doi: 10.1136/jim-2015-000035.415

Ji, Pengxiang, Genovesi, Laura, He, Yaowu, Hooper, John and Wainwright, Brandon (2016). Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma. 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), Liverpool England, 12-15 June 2016. United States: Oxford University Press.

Adams, Mark N., Harrington, Brittney S., He, Yaowu, Davies, Claire M., Wallace, Sarah J., Chetty, Naven P., Crandon, Alexander J., Oliveira, Niara B., Shannon, Catherine M., Coward, Jermaine I., Lumley, John W., Perrin, Lewis C., Armes, Jane E. and Hooper, John D. (2015). EGF-induced recycling of the cancer promoting protein CDCP1. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

Hooper, J., He, Y., Wu, A., Harrington, B., Davies, C., Wallace, S., Gilks, B., Perrin, L. and Armes, J. (2014). A New Marker of Poor Outcome and Potential Therapeutic Target in Ovarian Clear Cell Carcinoma. 15th Biennial Meeting of the International Gynecologic Cancer Society, Melbourne, VIC Australia, 8-11 November 2014. London, United Kingdom: Lippincott Williams and Wilkins. doi: 10.1097/01.IGC.0000457075.08973.89

Harrington, B., Davies, C. M., Wallace, S. J., He, Y., Armes, J. E., Perrin, L. C. and Hooper, J. D. (2014). Targeting the cell surface protein Cdcp1 in a model of advanced ovarian cancer. London, United Kingdom: B M J Group.

Wallace, D. F., Secondes, E. S., Rishi, G., Ostini, L., Mcdonald, C. J., Lane, S. W., Hooper, J. D., Lopez-Otin, C. and Subramaniam, V. N. (2014). Investigation of mice deficient in matriptase-2, Hfe and transferrin receptor 2 reveals a novel non-hepatic role for Tfr2 in erythropoiesis. Australian Gastroenterology Week 2014, Broadbeach, Australia, 22-24 October 2014. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_6

Wallace, Daniel F., McDonald, Cameron J., Secondes, Eriza S., Ostini, Lesa, Rishi, Gautam, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2013). An Essential Role For Transferrin Receptor 2 In Erythropoiesis During Iron Restriction. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY.

Bennett, Nigel C., McDonald, Cameron J., Wallace, Daniel F., Hooper, John D., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2013). Clinically Identified Tmprss6 Mutations Result in Either Trafficking Defects or Inability to Cleave Hemojuvelin. BioIron 2013: 5th Meeting of the International BioIron Society, University College London UK, April 14 – 18, 2013. Hoboken, United States: Jossey Bass, Ed. & Pub.. doi: 10.1002/ajh.23453

Lassemillante, Annie-Claude, Hooper, John, Prins, John, Doi, Suhail and Wright, Olivia (2013). The prevalence of osteoporosis in men with prostate cancer on androgen deprivation therapy: a systematic review and meta-analysis. Prostate Cancer World Congress & 14th Australasian Prostate Cancer Conference, Melbourne Australia, 6–10 August 2013. West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/bju.12293

Clements, J. A., Dong, Y., Loessner, D., Tan, O., Sieh, S., Reichert, J., Burke, L., Stephens, C., Lawrence, M., Stansfield, S., Swedberg, J., Ramsay, A., Hooper, J., Harris, J. and Hutmacher, D. (2009). Kallikrein-related proteases as novel therapeutic targets in prostate and ovarian cancer. 40th Annual Conference of the Society for Reproductive Biology, Clayton, VIC, Australia: CSIRO Publishing. doi: 10.1071/srb09abs009

Ramsay, Andrew J., Reid, Janet C., Adams, Mark N., Samaratunga, Hemamali, Dong, Ying, Clements, Judith A. and Hooper, John D. (2008). Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs). 2nd International Symposium on Kallikrein and Kallikrein-Related Peptidases (ISK 2007), Santorini, Greece, 16-18 October 2007. Berlin, Germany: Walter de Gruyter. doi: 10.1515/BC.2008.078

Rae, F., Hooper, J.D., Nicol, D. L. and Clements, J.A. (2001). Identification and characterization of a novel gene STAG1 is up-regulated in renal cell carcinoma. 2001 Annual Scientific Meeting of the Urological Society of Australasia, Coolum, Australia, March 2001. Australia: Blackwell Publishing Asia.

Antalis, T. M., Boucaut, K. J., Normyle, J. F., Fitzpatrick, D. R. and Hooper, J. (2000). Localization, structure and regulation of the human PRSS14 gene encoding the serine proteinase Testisin. 91st Annual Meeting of the American Association for Cancer Research, San Francisco, 1-5 Apr, 2000. Philadelphia, U.S.A.: American Association for Cancer Research.

Kryza, Thomas, Khan, Tashbib, Lovell, Scott, Harrington, Brittney S., Yin, Julia, Porazinski, Sean, Pajic, Marina, Koistinen, Hannu, Rantala, Juha, Dreyer, Tobias, Magdolen, Viktor, Reuning, Ute, He, Yaowu, Tate, Edward and Hooper, John David (2020). Substrate-biased activity-based probes identify the urokinase-plasminogen axis as a master regulator of metastatic signaling by orphan membrane receptor CDCP1.

Puttick, S., Kryza, T., Hooper, J. D., He, Y., Harrington, B., Quigley, J. and Deryugina, E. (2020). Binding proteins to CUB domain-containing protein (CDCP1). PCT/AU2020/051216.

Professor John Hooper

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