Professor Matt Sweet

Featured projects	Duration
Understanding host-pathogen interactions through development of new co-transcriptomic single cell RNA sequencing technologies Genome Innovation Hub Collaborative Project (UQ infrastructure)	2020

Afroz, Syeda Farhana, Condon, Nicholas D., Sweet, Matthew J. and Kapetanovic, Ronan (2022). Quantifying regulated mitochondrial fission in macrophages. Effector-triggered immunity: methods and protocols. (pp. 281-301) edited by Thomas A. Kufer and Maria Kaparakis-Liaskos. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-2449-4_18

Ravasi, Timothy, Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Schembri, Mark A. and Sweet, Matthew J. (2016). Co-transcriptomic analysis by RNA sequencing to simultaneously measure regulated gene expression in host and bacterial pathogen. Toll-like receptors: practice and methods. (pp. 145-158) edited by Claire E. McCoy. Heidelberg, Germany: Springer. doi: 10.1007/978-1-4939-3335-8_10

Kapetanovic, Ronan, Ariffin, Juliana K. and Sweet, Matthew J. (2014). Evolutionary divergence in human versus mouse innate immune genes. Evolutionary biology: genome evolution, speciation, coevolution and origin of life. (pp. 115-155) edited by Pierre Pontarotti. Heidelberg, Germany: Springer. doi: 10.1007/978-3-319-07623-2_6

Sweet, Matthew J. and Bokil, Nilesh J. (2010). The role of monocytes and macrophages in innate immunity: macrophage anti-microbial pathways.. Regulation of innate immune function. (pp. 1-31) edited by Clay B. Marsh, Susheela Tridandapani and Melissa G. Piper. Kerala, India: Transworld Research Network.

Stacey, K. J., Sester, D. P., Naik, S., Roberts, T., Sweet, M. J. and Hume, D. A. (2002). Phosphorothioate backbone modification changes the pattern of responses to CpG. Microbial DNA and host immunity. (pp. 63-77) Totowa, New Jersey: Humana Press. doi: 10.1007/978-1-59259-305-7_6

Hume, D. A., Stacey, K. J., Cassady, A. ., Browne, C. M., Sweet, M. J. and Bertoncello, I. (1996). Growth and differentiation of murine macrophages. Handbook of experimental immunology. (pp. 160.1-160.10) Boston: Wiley-Blackwell.

Wang, Yizhuo, Curson, James E.B., Ramnath, Divya, Das Gupta, Kaustav, Reid, Robert C., Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2024). Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain. Biochemical Journal, 481 (21), 1569-1584. doi: 10.1042/bcj20240380

Sweet, Matthew J., Ramnath, Divya, Singhal, Amit and Kapetanovic, Ronan (2024). Inducible antibacterial responses in macrophages. Nature Reviews Immunology. doi: 10.1038/s41577-024-01080-y

Poon, Eunice K., Liu, Ligong, Wu, Kai‐Chen, Lim, Junxian, Sweet, Matthew J., Lohman, Rink‐Jan, Iyer, Abishek and Fairlie, David P. (2024). A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis. British Journal of Pharmacology, 181 (23), 4804-4821. doi: 10.1111/bph.17306

Patrick, Ralph, Naval-Sanchez, Marina, Deshpande, Nikita, Huang, Yifei, Zhang, Jingyu, Chen, Xiaoli, Yang, Ying, Tiwari, Kanupriya, Esmaeili, Mohammadhossein, Tran, Minh, Mohamed, Amin R., Wang, Binxu, Xia, Di, Ma, Jun, Bayliss, Jacqueline, Wong, Kahlia, Hun, Michael L., Sun, Xuan, Cao, Benjamin, Cottle, Denny L., Catterall, Tara, Barzilai-Tutsch, Hila, Troskie, Robin-Lee, Chen, Zhian, Wise, Andrea F., Saini, Sheetal, Soe, Ye Mon, Kumari, Snehlata, Sweet, Matthew J. ... Nefzger, Christian M. (2024). The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening. Cell Metabolism, 36 (8), 1858-1881.e23. doi: 10.1016/j.cmet.2024.06.006

Nhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4

Das Gupta, Kaustav, Curson, James E. B., Tarique, Abdullah A., Kapetanovic, Ronan, Schembri, Mark A., Fantino, Emmanuelle, Sly, Peter D. and Sweet, Matthew J. (2024). CFTR is required for zinc-mediated antibacterial defense in human macrophages. Proceedings of the National Academy of Sciences, 121 (8) e2315190121, 1-11. doi: 10.1073/pnas.2315190121

Duszyc, Kinga, von Pein, Jessica B., Ramnath, Divya, Currin-Ross, Denni, Verma, Suzie, Lim, Fayth, Sweet, Matthew J., Schroder, Kate and Yap, Alpha S. (2023). Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia. Developmental Cell, 58 (21), 2235-2248.e6. doi: 10.1016/j.devcel.2023.08.009

Curson, James E. B., Liu, Liping, Luo, Lin, Muusse, Timothy W., Lucas, Richard M., Gunther, Kimberley S., Vajjhala, Parimala R., Abrol, Rishika, Jones, Alun, Kapetanovic, Ronan, Stacey, Katryn J., Stow, Jennifer L. and Sweet, Matthew J. (2023). TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages. European Journal of Immunology, 53 (7) e2250056, e2250056. doi: 10.1002/eji.202250056

Wang, Yizhuo, Abrol, Rishika, Mak, Jeffrey Y. W., Das Gupta, Kaustav, Ramnath, Divya, Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2023). Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease. The FEBS Journal, 290 (11), 2805-2832. doi: 10.1111/febs.16437

Stow, Jennifer L. and Sweet, Matthew J. (2023). Macrophage Nrf 2 the rescue. Journal of Cell Biology, 222 (6) e202305036. doi: 10.1083/jcb.202305036

Zhang, Yue, Xian, He, Strounina, Ekaterina, Gunther, Kimberley S., Sweet, Matthew J., Chen, Chen, Yu, Chengzhong and Wang, Yue (2023). Mesoporous Organosilica Nanoparticles with Tetrasulphide Bond to Enhance Plasmid DNA Delivery. Pharmaceutics, 15 (3) 1013, 1-11. doi: 10.3390/pharmaceutics15031013

Afroz, Syeda Farhana, Raven, Karoline D, Lawrence, Grace M. E. P., Kapetanovic, Ronan, Schroder, Kate and Sweet, Matthew J. (2023). Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?. Biochemical Society. Transactions, 51 (1), 41-56. doi: 10.1042/bst20220014

Das Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B., Curson, James E. B., Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S., Murthy, Ambika M. V., Stocks, Claudia J., Kapetanovic, Ronan, Reid, Robert C., Iyer, Abishek, Ilka, Zoe C., Nauseef, William M., Plan, Manuel, Luo, Lin, Stow, Jennifer L., Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R., Schembri, Mark A., Fairlie, David P. and Sweet, Matthew J. (2023). HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences, 120 (4) e2212813120, 1-12. doi: 10.1073/pnas.2212813120

Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022

Wang, Alison S., Steers, Nicholas J., Parab, Adwaita R., Gachon, Frédéric, Sweet, Matthew J. and Mysorekar, Indira U. (2022). Timing is everything: impact of development, ageing and circadian rhythm on macrophage functions in urinary tract infections. Mucosal Immunology, 15 (6), 1-13. doi: 10.1038/s41385-022-00558-z

Liu, Liping, Lucas, Richard M., Nanson, Jeffrey D., Li, Yan, Whitfield, Jason, Curson, James E. B., Tuladhar, Neeraj, Alexandrov, Kirill, Mobli, Mehdi, Sweet, Matthew J., Kobe, Bostjan, Stow, Jennifer and Luo, Lin (2022). The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs. Journal of Biological Chemistry, 298 (5) 101857, 101857. doi: 10.1016/j.jbc.2022.101857

Jouffe, Céline, Weger, Benjamin D., Martin, Eva, Atger, Florian, Weger, Meltem, Gobet, Cédric, Ramnath, Divya, Charpagne, Aline, Morin-Rivron, Delphine, Powell, Elizabeth E., Sweet, Matthew J., Masoodi, Mojgan, Uhlenhaut, N. Henriette and Gachon, Frédéric (2022). Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease. Proceedings of the National Academy of Sciences, 119 (10) e2200083119, e2200083119. doi: 10.1073/pnas.2200083119

Curson, James E.B., Luo, Lin, Liu, Liping, Burgess, Belinda J., Bokil, Nilesh J., Wall, Adam A, Brdicka, Tomas, Kapetanovic, Ronan, Stow, Jennifer L and Sweet, Matthew J (2022). An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages. Immunology and Cell Biology, 100 (4), 267-284. doi: 10.1111/imcb.12540

Ramnath, Divya, Das Gupta, Kaustav, Wang, Yizhuo, Abrol, Rishika, Curson, James E. B., Lim, Junxian, Reid, Robert C., Mansell, Ashley, Blumenthal, Antje, Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2022). The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms. Journal of Leukocyte Biology, 111 (2), 327-336. doi: 10.1002/jlb.2mr1021-260r

Tran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166

Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79 (1) 38, 38. doi: 10.1007/s00018-021-04041-z

Zhao, Yang, Oreskovic, Ena, Zhang, Quanwei, Lu, Quan, Gilman, Abbey, Lin, Yifei S., He, Junyue, Zheng, Zhizhong, Lu, J. Yuyang, Lee, Jina, Ke, Zhonghe, Ablaeva, Julia, Sweet, Matthew J., Horvath, Steve, Zhang, Zhengdong, Nevo, Eviatar, Seluanov, Andrei and Gorbunova, Vera (2021). Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Nature Immunology, 22 (10), 1219-1230. doi: 10.1038/s41590-021-01027-8

Lucas, Richard M., Liu, Liping, Curson, James E. B., Koh, Yvette W. H., Tuladhar, Neeraj, Condon, Nicholas D., Das Gupta, Kaustav, Burgener, Sabrina S., Schroder, Kate, Ingley, Evan, Sweet, Matthew J., Stow, Jennifer L. and Luo, Lin (2021). SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages. Cell Reports, 36 (10) 109662, 1-20. doi: 10.1016/j.celrep.2021.109662

Bosch, Marta, Sweet, Matthew J., Parton, Robert G. and Pol, Albert (2021). Lipid droplets and the host–pathogen dynamic: FATal attraction?. Journal of Cell Biology, 220 (8) e202104005. doi: 10.1083/jcb.202104005

Sun, Xuan, Cao, Benjamin, Naval-Sanchez, Marina, Pham, Tony, Sun, Yu Bo Yang, Williams, Brenda, Heazlewood, Shen Y, Deshpande, Nikita, Li, Jinhua, Kraus, Felix, Rae, James, Nguyen, Quan, Yari, Hamed, Schröder, Jan, Heazlewood, Chad K, Fulton, Madeline, Hatwell-Humble, Jessica, Das Gupta, Kaustav, Kapetanovic, Ronan, Chen, Xiaoli, Sweet, Matthew J, Parton, Robert G, Ryan, Michael T, Polo, Jose M, Nefzger, Christian M and Nilsson, Susan K (2021). Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells. Nature Communications, 12 (1) 2665, 1-17. doi: 10.1038/s41467-021-22863-0

Mak, Jeffrey Y. W., Wu, Kai-Chen, Gupta, Praveer K., Barbero, Sheila, McLaughlin, Maddison G., Lucke, Andrew J., Tng, Jiahui, Lim, Junxian, Loh, Zhixuan, Sweet, Matthew J, Reid, Robert C., Liu, Ligong and Fairlie, David P. (2021). HDAC7 inhibition by phenacetyl and phenylbenzoyl hydroxamates. Journal of Medicinal Chemistry, 64 (4), 2186-2204. doi: 10.1021/acs.jmedchem.0c01967

Pein, Jessica B., Stocks, Claudia J., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2021). An alloy of zinc and innate immunity: galvanizing host defence against infection. Cellular Microbiology, 23 (1) e13268, 1-11. doi: 10.1111/cmi.13268

Salmon, Jessica M., Reed, Casie Leigh, Bender, Maddyson, Mitchell, Helen Lorraine, Fox, Vanessa, Magor, Graham William, Sweet, Matthew and Perkins, Andrew Charles (2020). KLF3 represses the inflammatory response in macrophages. Blood, 136 (Supplement 1), 36-36. doi: 10.1182/blood-2020-142373

Sweet, Matthew J., Jones, Sarah A. and Harris, James (2020). A sprinkle of salt in the pressure cooker of innate immunity and inflammation. Immunology and Cell Biology, 99 (1) imcb.12413, 9-12. doi: 10.1111/imcb.12413

Chamoun, Michelle N., Sullivan, Matthew J., Goh, Kelvin G. K., Acharya, Dhruba, Ipe, Deepak S., Katupitiya, Lahiru, Gosling, Dean, Peters, Kate M., Sweet, Matthew J., Sester, David P., Schembri, Mark A. and Ulett, Glen C. (2020). Restriction of chronic Escherichia coli urinary tract infection depends upon T cell-derived interleukin-17, a deficiency of which predisposes to flagella-driven bacterial persistence. FASEB Journal, 34 (11), 14572-14587. doi: 10.1096/fj.202000760R

Kapetanovic, Ronan, Afroz, Syeda Farhana, Ramnath, Divya, Lawrence, Grace M.E.P., Okada, Takashi, Curson, James E.B., Bruin, Jost, Fairlie, David P., Schroder, Kate, St John, Justin C., Blumenthal, Antje and Sweet, Matthew J. (2020). Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophages. Immunology and Cell Biology, 98 (7) imcb.12363, 528-539. doi: 10.1111/imcb.12363

Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19

Luo, Lin, Curson, James E. B., Liu, Liping, Wall, Adam A., Tuladhar, Neeraj, Lucas, Richard M., Sweet, Matthew J. and Stow, Jennifer L. (2019). SCIMP is a universal Toll‐like receptor adaptor in macrophages. Journal of Leukocyte Biology, 107 (2) JLB.2MA0819-138RR, 251-262. doi: 10.1002/jlb.2ma0819-138rr

Starobova, H., Mueller, A., Allavena, R., Lohman, R. J., Sweet, M. J. and Vetter, I. (2019). Minocycline prevents the development of mechanical allodynia in mouse models of vincristine-induced peripheral neuropathy. Frontiers in Neuroscience, 13 (JUN) 653, 653. doi: 10.3389/fnins.2019.00653

Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768

Yang, Yoon Mee, Noureddin, Mazen, Liu, Cheng, Ohashi, Koichiro, Kim, So Yeon, Ramnath, Divya, Powell, Elizabeth E., Sweet, Matthew J., Roh, Yoon Seok, Hsin, I-Fang, Deng, Nan, Liu, Zhenqiu, Liang, Jiurong, Mena, Edward, Shouhed, Daniel, Schwabe, Robert F., Jiang, Dianhua, Lu, Shelly C., Noble, Paul W. and Seki, Ekihiro (2019). Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science Translational Medicine, 11 (496) eaat9284, eaat9284. doi: 10.1126/scitranslmed.aat9284

Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116

Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R

Chen, Kaiwen W., Monteleone, Mercedes, Boucher, Dave, Sollberger, Gabriel, Ramnath, Divya, Condon, Nicholas D., von Pein, Jessica B., Broz, Petr, Sweet, Matthew J. and Schroder, Kate (2018). Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps. Science Immunology, 3 (26) eaar6676, eaar6676. doi: 10.1126/sciimmunol.aar6676

Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2018). Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion. Cell Reports, 24 (6), 1425-1433. doi: 10.1016/j.celrep.2018.07.027

Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) ARTN e120274. doi: 10.1172/jci.insight.120274

Curson, James E. B., Luo, Lin, Sweet, Matthew J. and Stow, Jennifer L. (2018). pTRAPs: Transmembrane adaptors in innate immune signaling. Journal of Leukocyte Biology, 103 (6), 1011-1019. doi: 10.1002/JLB.2RI1117-474R

Soderholm, Amelia T., Barnett, Timothy C., Korn, Othmar, Rivera-Hernandez, Tania, Seymour, Lisa M., Schulz, Benjamin L., Nizet, Victor, Wells, Christine A., Sweet, Matthew J. and Walker, Mark J. (2018). Group A Streptococcus M1T1 intracellular infection of primary tonsil epithelial cells dampens levels of secreted IL-8 through the action of SpyCEP. Frontiers in Cellular and Infection Microbiology, 8 (MAY) 160, 160. doi: 10.3389/fcimb.2018.00160

Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786

Shakespear, Melanie R., Iyer, Abishek, Cheng, Catherine Youting, Das Gupta, Kaustav, Singhal, Amit, Fairlie, David P. and Sweet, Matthew J. (2018). Lysine deacetylases and regulated glycolysis in macrophages. Trends in Immunology, 39 (6), 473-488. doi: 10.1016/j.it.2018.02.009

Stocks, Claudia J., Schembri, Mark A., Sweet, Matthew J. and Kapetanovic, Ronan (2018). For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophages. Journal of Leukocyte Biology, 103 (1), 35-51. doi: 10.1002/JLB.4RI0917-358R

Soderholm, Amelia T., Barnett, Timothy C., Sweet, Matthew J. and Walker, Mark J. (2017). Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies. Journal of Leukocyte Biology, 103 (2), 193-213. doi: 10.1189/jlb.4MR0617-227RR

Goh, Kelvin G. K., Phan, Minh-Duy, Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2017). Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli. MBio, 8 (5) e01558-17. doi: 10.1128/mBio.01558-17

Duszyc, Kinga, Gomez, Guillermo A., Schroder, Kate, Sweet, Matthew J. and Yap, Alpha S. (2017). In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis. Tissue Barriers, 5 (4) e1345353, e1345353. doi: 10.1080/21688370.2017.1345353

Luo, Lin, Tong, Samuel J., Wall, Adam A., Khromykh, Tatiana, Sweet, Matthew J. and Stow, Jennifer L. (2017). Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP. Immunology and Cell Biology, 95 (6), 564-570. doi: 10.1038/icb.2017.10

Wall, Adam A., Luo, Lin, Hung, Yu, Tong, Samuel J., Condon, Nicholas D., Blumenthal, Antje, Sweet, Matthew J. and Stow, Jennifer L. (2017). Small GTPase Rab8a-recruited phosphatidylinositol 3-kinase γ regulates signaling and cytokine outputs from endosomal toll-like receptors. Journal of Biological Chemistry, 292 (11), 4411-4422. doi: 10.1074/jbc.M116.766337

Luo, Lin, Bokil, Nilesh J., Wall, Adam A., Kapetanovic, Ronan, Lansdaal, Natalie M., Marceline, Faustine, Burgess, Belinda J., Tong, Samuel J., Guo, Zhong, Alexandrov, Kirill, Ross, Ian L., Hibbs, Margaret L., Stow, Jennifer L. and Sweet, Matthew J. (2017). SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nature Communications, 8 (1) 14133, 14133. doi: 10.1038/ncomms14133

Sweet, Matthew and Mansell, Ashley (2017). The nicer side of innate immunity: wound healing and tissue regeneration. Seminars in Cell and Developmental Biology, 61, 1-2. doi: 10.1016/j.semcdb.2016.12.006

Do, Anh, Reid, Robert C., Lohman, Rink-Jan, Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2017). An HDAC6 inhibitor confers protection and selectively inhibits B-cell infiltration in DSS-induced colitis in mice. The Journal of Pharmacology and Experimental Therapeutics, 360 (1), 140-151. doi: 10.1124/jpet.116.236711

Shepherd, Mark, Achard, Maud E. S., Idris, Adi, Totsika, Makrina, Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Ribeiro, Cláudia A., Holyoake, Louise V., Ladakis, Dimitrios, Ulett, Glen C., Sweet, Matthew J., Poole, Robert K., McEwan, Alastair G. and Schembri, Mark A. (2016). The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection. Scientific Reports, 6 (1) 35285, 35285. doi: 10.1038/srep35285

Irvine, Katharine M., Xuan Banh, Gadd, Victoria L., Wojcik, Kyle K., Ariffin, Juliana K., Jose, Sara, Lukowski, Samuel, Baillie, Gregory J., Sweet, Matthew J. and Powell, Elizabeth E. (2016). CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites. JCI Insight, 1 (8) e86914, e86914. doi: 10.1172/jci.insight.86914

Ullah, M. Obayed, Sweet, Matthew J., Mansell, Ashley, Kellie, Stuart and Kobe, Bostjan (2016). TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target. Journal of Leukocyte Biology, 100 (1), 27-45. doi: 10.1189/jlb.2RI1115-531R

Seow, Vernon, Lim, Junxian, Cotterell, Adam J., Yau, Mei-Kwan, Xu, Weijun, Lohman, Rink-Jan, Kok, W. Mei, Stoermer, Martin J., Sweet, Matthew J., Reid, Robert C., Suen, Jacky Y. and Farilie, David P. (2016). Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists. Scientific Reports, 6 (1) 24575, 24575.1-24575.12. doi: 10.1038/srep24575

Chen, Kaiwen W., Bezbradica, Jelena S., Gross, Christina J., Wall, Adam A., Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2016). The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists. European Journal of Immunology, 46 (4), 1004-1010. doi: 10.1002/eji.201545943

Ariffin, Juliana K., das Gupta, Kaustav, Kapetanovic, Ronan, Iyer, Abishek, Reid, Robert C., Fairlie, David P. and Sweet, Matthew J. (2016). Histone deacetylase inhibitors promote mitochondrial reactive oxygen species production and bacterial clearance by human macrophages. Antimicrobial Agents and Chemotherapy, 60 (3), 1521-1529. doi: 10.1128/AAC.01876-15

Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061

Lohman, Rink-Jan, Iyer, Abishek, Fairlie, Thomas J., Cotterell, Adam, Gupta, Praveer, Reid, Robert C., Vesey, David A., Sweet, Matthew J. and Fairlie, David P. (2016). Differential anti-inflammatory activity of HDAC inhibitors in human macrophages and rat arthritis. Journal of Pharmacology and Experimental Therapeutics, 356 (2), 387-396. doi: 10.1124/jpet.115.229328

Das Gupta, Kaustav, Melanie Shakespear R., Iyer, Abishek, Fairlie, David P. and Sweet, Matthew J. (2016). Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases. Clinical and Translational Immunology, 5 (1) e62, e62. doi: 10.1038/cti.2015.46

Arnez, Katja Hrovat, Kindlova, Michaela, Bokil, Nilesh J., Murphy, James M., Sweet, Matthew J. and Guncar, Gregor (2016). Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death. Bioscience Reports, 36 (1) e00291, e00291-e00291. doi: 10.1042/BSR20150246

D'Souza, Charlotte, Henriques, Sonia Troeira, Wang, Conana K., Cheneval, Olivier, Chan, Lai Yue, Bokil, Nilesh J., Sweet, Matthew J. and Craik, David J. (2016). Using the MCoTI-II cyclotide scaffold to design a stable cyclic peptide antagonist of SET, a protein overexpressed in human cancer. Biochemistry, 55 (2), 396-405. doi: 10.1021/acs.biochem.5b00529

Schaale, K., Peters, K. M., Murthy, A. M., Fritzsche, A. K., Phan, M.-D., Totsika, M., Robertson, A. A. B., Nichols, K. B., Cooper, M. A., Stacey, K. J., Ulett, G. C., Schroder, K., Schembri, M. A. and Sweet, M. J. (2016). Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.. Mucosal Immunology, 9 (1), 124-136. doi: 10.1038/mi.2015.44

Ramnath, Divya, Powell, Elizabeth E., Scholz, Glen M. and Sweet, Matthew J. (2016). The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair. Seminars in Cell and Developmental Biology, 61, 22-30. doi: 10.1016/j.semcdb.2016.08.014

Ariffin, Juliana K., Kapetanovic, Ronan, Schaale, Kolja, Gatica-Andrades, Marcela, Blumenthal, Antje, Schroder, Kate and Sweet, Matthew J. (2016). The E3 ubiquitin ligase RNF144B is LPS-inducible in human but not mouse macrophages, and promotes inducible IL-1β expression. Journal of Leukocyte Biology, 100 (1), 155-161. doi: 10.1189/jlb.2AB0815-339R

Kakkanat, Asha, Totsika, Makrina, Schaale, Kolja, Duell, Benjamin L., Lo, Alvin W., Phan, Minh-Duy, Moriel, Danilo G., Beatson, Scott A., Sweet, Matthew J., Ulett, Glen C. and Schembri, Mark A. (2015). The role of H4 flagella in Escherichia coli ST131 virulence. Scientific Reports, 5 (16149) 16149, 1-14. doi: 10.1038/srep16149

Stammler, Dominik, Eigenbrod, Tatjana, Menz, Sarah, Frick, Julia S., Sweet, Matthew J., Shakespear, Melanie R., Jantsch, Jonathan, Siegert, Isabel, Wolfle, Sabine, Langer, Julian D., Oehme, Ina, Schaefer, Liliana, Fischer, Andre, Knievel, Judith, Heeg, Klaus, Dalpke, Alexander H. and Bode, Konrad A. (2015). Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1b via a caspase-1-independent mechanism. Journal of Immunology, 195 (11), 5421-5431. doi: 10.4049/jimmunol.1501195

Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7

Carey, Alison J., Sullivan, Matthew J., Duell, Benjamin L., Crossman, David K., Chattopadhyay, Debasish., Brooks, Andrew J., Tan, Chee K., Crowley, Michael., Sweet, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2015). Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infection. The Journal of infectious diseases, 213 (4), 659-668. doi: 10.1093/infdis/jiv424

Ramnath, Divya, Tunny, Kathryn, Hohenhaus, Daniel M., Pitts, Claire M., Bergot, Anne-Sophie, Hogarth, P. Mark, Hamilton, John A., Kapetanovic, Ronan, Sturm, Richard A., Scholz, Glen M. and Sweet, Matthew J. (2015). TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes. Immunology and Cell Biology, 93 (9), 771-779. doi: 10.1038/icb.2015.77

Ahrens, Ingo, Chen, Yung-Chih, Topcic, Danijal, Bode, Michael, Haenel, David, Hagemeyer, Christoph E., Seeba, Hannah, Duerschmied, Daniel, Bassler, Nicole, Jandeleit-Dahm, Karin A., Sweet, Matthew J., Agrotis, Alex, Bobik, Alex and Peter, Karlheinz (2015). HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi. Thrombosis and Haemostasis, 114 (5), 994-1003. doi: 10.1160/TH14-12-1073

Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859

Kapetanovic, Ronan, Bokil, Nilesh J. and Sweet, Matthew J. (2015). Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageing. Ageing Research Reviews, 24 (Pt A), 40-53. doi: 10.1016/j.arr.2015.02.005

Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Totsika, Makrina, Kakkanat, Asha, Schaale, Kolja, Cannistraci, Carlo V., Ryu, Taewoo, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A., Sweet, Matthew J. and Ravasi, Timothy (2015). The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions. Cellular Microbiology, 17 (5), 730-746. doi: 10.1111/cmi.12397

Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851

Kwa, Mei Qi, Huynh, Jennifer, Aw, Jiamin, Zhang, Lianyi, Nguyen, Thao, Reynolds, Eric C., Sweet, Matthew J., Hamilton, John A. and Scholz, Glen M. (2014). Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation. Journal of Biological Chemistry, 289 (45), 31077-31087. doi: 10.1074/jbc.M114.589382

Chen, Kaiwen W., Groß, Christina J., Vasquez Sotomayor, Flor, Stacey, Katryn J., Tschopp, Jurg, Sweet, Matthew J. and Schroder, Kate (2014). The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge. Cell Reports, 8 (2), 570-582. doi: 10.1016/j.celrep.2014.06.028

Luo, Lin, Wall, Adam A., Yeo, Jeremy C., Condon, Nicholas D., Norwood, Suzanne J., Schoenwaelder, Simone, Chen, Kaiwen W., Jackson, Shaun, Jenkins, Brendan J., Hartland, Elizabeth L., Schroder, Kate, Collins, Brett M., Sweet, Matthew J. and Stow, Jennifer L. (2014). Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling. Nature Communications, 5 (1) 4407, 4407.1-4407.13. doi: 10.1038/ncomms5407

Kwa, Mei Qi, Nguyen, Thao, Huynh, Jennifer, Ramnath, Divya, De Nardo, Dominic, Lam, Pei Yeng, Reynolds, Eric C., Hamilton, John A., Sweet, Matthew J. and Scholz, Glen M. (2014). Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells. Journal of Biological Chemistry, 289 (28), 19758-19768. doi: 10.1074/jbc.M114.584540

Schroder, Wayne A., Major, Lee D., Le, Thuy T., Gardner, Joy, Sweet, Matthew J., Janciauskiene, Sabina and Suhrbier, Andreas (2014). Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Medicine, 3 (3), 500-513. doi: 10.1002/cam4.229

Archbold, Julia K., Martin, Jennifer L. and Sweet, Matthew J. (2014). Towards selective lysophospholipid GPCR modulators. Trends in Pharmacological Sciences, 35 (5), 219-226. doi: 10.1016/j.tips.2014.03.004

Koulis, Christine, Chen, Yung-Chih, Hausding, Christian, Ahrens, Ingo, Kyaw, Tin Soe, Tay, Christopher, Allen, Terri, Jandeleit-Dahm, Karin, Sweet, Matthew J., Akira, Shizuo, Bobik, Alexander, Peter, Karlheinz and Agrotis, Alex (2014). Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 34 (3), 516-525. doi: 10.1161/ATVBAHA.113.302407

Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014). Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 (5), 1480-1490. doi: 10.1002/eji.201343959

Ullah, M. Obayed, Ve, Thomas, Mangan, Matthew, Alaidarous, Mohammed, Sweet, Matthew J., Mansell, Ashley and Kobe, Bostjan (2013). The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins. Acta Crystallographica Section D: Biological Crystallography, 69 (12), 2420-2430. doi: 10.1107/S0907444913022385

Alaidarous, Mohammed Abdullah, Ve, Thomas, Casey, Lachlan, Valkov, Eugene, Ericsson, Daniel, Obayed, Ullah, M., Schembri, Mark A., Mansell, Ashley, Sweet, Matthew J. and Kobe, Bostjan (2013). Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpB. Journal of Biological Chemistry, 289 (2), 654-668. doi: 10.1074/jbc.M113.523274

Hohenhaus, Daniel M., Schaale, Kolja, Le Cao, Kim-Anh, Seow, Vernon, Iyer, Abishek, Fairlie, David P. and Sweet, Matthew J. (2013). An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation. Immunobiology, 218 (11), 1345-1353. doi: 10.1016/j.imbio.2013.07.001

Alaidarous, Mohammed, Ve, Thomas, Ullah, M. Obayed, Valkov, Eugene, Mansell, Ashley, Schembri, Mark A., Sweet, Matthew J. and Kobe, Bostjan (2013). Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (10), 1167-1170. doi: 10.1107/S1744309113024408

Seow, Vernon, Lim, Junxian, Iyer, Abishek, Suen, Jacky Y., Ariffin, Juliana K., Hohenhaus, Daniel M., Sweet, Matthew J. and Fairlie, David P. (2013). Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a. Journal of Immunology, 191 (8), 4308-4316. doi: 10.4049/jimmunol.1301355

Achard, Maud E. S, Chen, Kaiwen W., Sweet, Matthew J., Watts, Rebecca E., Schroder, Kate, Schembri, Mark A. and McEwan, Alastair G. (2013). An antioxidant role for catecholate siderophores in Salmonella. Biochemical Journal, 454 (3), 543-549. doi: 10.1042/BJ20121771

Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281

Stafford, Sian L., Bokil, Nilesh J., Achard, Maud E. S., Kapetanovic, Ronan, Schembri, Mark A., McEwan, Alastair G. and Sweet, Matthew J. (2013). Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper. Bioscience Reports, 33 (4) ARTN e00049, 541-554. doi: 10.1042/BSR20130014

Ullah, M. Obayed, Ve, Thomas, Dkhar, Jameris, Alaidarous, Mohammed, Ericsson, Daniel J., Sweet, Matthew J., Mansell, Ashley and Kobe, Bostjan (2013). Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (7), 766-770. doi: 10.1107/S174430911301419X

Gadd, Victoria L., Melino, Michelle, Roy, Sandrine, Horsfall, Leigh, O'Rourke, Peter, Williams, Millicent R., Irvine, Katharine M., Sweet, Matthew J., Jonsson, Julie R., Clouston, Andrew D. and Powell, Elizabeth E. (2013). Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and ﬁbrosis in chronic hepatitis C. Liver International, 33 (4), 569-579. doi: 10.1111/liv.12050

Juliana Ariffin and Sweet, Matthew J. (2013). Differences in the repertoire, regulation and function of TOLL-like receptors and inflammasome-forming Nod-like receptors between human and mouse. Current Opinion in Microbiology, 16 (3), 303-310. doi: 10.1016/j.mib.2013.03.002

Ulett, G. C., Makrina Totsika, Kolja Schaale, Carey, A. J., Sweet, Matthew J. and Schembri, Mark A. (2013). Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection. Current Opinion in Microbiology, 16 (1), 100-107. doi: 10.1016/j.mib.2013.01.005

Chen, Kai-En, Richards, Ayanthi A., Caradoc-Davies, Tom T., Vajjhala, Parimala R., Robin, Gautier, Lua, Linda H. L., Hill, Justine M., Schroder, Kate, Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer (2013). The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallographica Section D: Biological Crystallography, 69 (5), 774-784. doi: 10.1107/S0907444913001558

Schroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012). Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 (12), 1325-1329. doi: 10.1016/j.imbio.2012.07.020

Cridland, Jasmyn A., Curley, Eva Z., Wykes, Michelle N ., Schroder, Kate, Sweet, Matthew J., Roberts, Tara L., Ragan, Mark A., Kassahn, Karin S. and Stacey, Katryn J. (2012). The mammalian PYHIN gene family: Phylogeny, evolution and expression. BMC Evolutionary Biology, 12 (1) 140, 140.1-140.33. doi: 10.1186/1471-2148-12-140

Gupta, Praveer, Reid, Robert C., Iyer, Abishek, Sweet, Matthew J. and Fairlie, David (2012). Towards isozyme-selective HDA inhibitors for interrogating disease. Current Topics in Medicinal Chemistry, 12 (14), 1479-1499. doi: 10.2174/156802612802652420

Chen, Kai-En, Richards, Ayanthi A., Arrifin, Juliana K., Ross, Ian L., Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer L. (2012). The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. Acta Crystallographica Section D: Biological Crystallography, 68 (6), 637-648. doi: 10.1107/S0907444912006592

Achard, Maud E. S., Stafford, Sian L., Bokil, Nilesh J., Chartres, Jy, Bernhardt, Paul V., Schembri, Mark A., Sweet, Matthew J. and McEwan, Alastair G. (2012). Copper redistribution in murine macrophages in response to Salmonella infection. Biochemical Journal, 444 (1), 51-57. doi: 10.1042/BJ20112180

Schroder, Kate, Irvine, Katharine M., Taylor, Martin S., Bokil, Nilesh J., Le Cao, Kim-Anh, Masterman, Kelly-Anne, Labzin, Larisa I., Semple, Colin A., Kapetanovic, Ronan, Fairbairn, Lynsey, Akalin, Altuna, Faulkner, Geoffrey J., Baillie, John Kenneth, Gongora, Milena, Daub, Carsten O., Kawaji, Hideya, McLachlan, Geoffrey J., Goldman, Nick, Grimmond, Sean M., Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Lenhard, Boris, Hume, David A. and Sweet, Matthew J. (2012). Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the USA, 109 (16), E944-E953. doi: 10.1073/pnas.1110156109

Melino, Michelle, Gadd, Victoria L., Walker, Gene V., Skoien, Richard, Barrie, Helen D., Jothimani, Dinesh, Horsfall, Leigh, Jones, Alun, Sweet, Matthew J., Thomas, Gethin P., Clouston, Andrew D., Jonsson, Julie R. and Powell, Elizabeth E. (2012). Macrophage secretory products induce an inflammatory phenotype in hepatocytes. World Journal of Gastroenterology, 18 (15), 1732-1744. doi: 10.3748/wjg.v18.i15.1732

Sweet, Matthew J., Shakespear, Melanie R., Kamal, Nabilah A. and Fairlie, David P. (2012). HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation. Immunology and Cell Biology, 90 (1), 14-22. doi: 10.1038/icb.2011.88

Fairlie, David P. and Sweet, Matthew J. (2012). HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks. Immunology and Cell Biology, 90 (1), 3-5. doi: 10.1038/icb.2011.105

Bokil, Nilesh J., Totsika, Makrina, Carey, Alison J., Stacey, Katryn J., Hancock, Viktoria, Saunders, Bernadette M., Ravasi, Timothy, Ulett, Glenn C., Schembri, Mark A. and Sweet, Matthew J. (2011). Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology, 216 (11), 1164-1171. doi: 10.1016/j.imbio.2011.05.011

Valkov, Eugene, Stamp, Anna, DiMaio, Frank, Baker, David, Verstak, Brett, Roversi, Pietro, Kellie, Stuart, Sweet, Matthew J., Mansell, Ashley, Gay, Nicholas J., Martin, Jennifer L. and Kobe, Bostjan (2011). Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection. Proceedings of the National Academy of Sciences of the United States of America, 108 (36), 14879-14884. doi: 10.1073/pnas.1104780108

Alexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354

Shakespear, Melanie R., Halili, Maria A., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2011). Histone deacetylases as regulators of inflammation and immunity. Trends in Immunology, 32 (7), 335-343. doi: 10.1016/j.it.2011.04.001

Roberts, Tara L., Turner, Marian L., Dunn, Jasmyn A., Lenert, Petar, Ross, Ian L., Sweet, Matthew J. and Stacey, Katryn J. (2011). B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9. Immunology and Cell Biology, 89 (4), 517-525. doi: 10.1038/icb.2010.112

Roberts, Tara L., Dunn, Jasmyn A., Sweet, Matthew J., Hume, David A. and Stacey, Katryn J. (2011). The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes. Molecular Immunology, 48 (8), 1027-1034. doi: 10.1016/j.molimm.2011.01.011

Van Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011). Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 (1) e15723, e15723-1-e15723-13. doi: 10.1371/journal.pone.0015723

Rosso, M., Heine, H., Meusch, U., Quandt, D., Klein, C., Sweet, M. J. and Hauschildt, S. (2011). LPS-Induced Cytokine Production in Human Monocytes and Macrophages. Critical Reviews in Immunology, 31 (5), 379-446. doi: 10.1615/CritRevImmunol.v31.i5.20

Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424

Sweet, Matthew J. (2010). Dead cells certainly do matter, particularly when they can speak from the grave. Journal of Leukocyte Biology, 88 (6), 1065-1066. doi: 10.1189/jlb.0810443

Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100

Low, Pei Ching, Misaki, Ryo, Schroder, Kate, Stanley, Amanda C., Sweet, Matthew J., Teasdale, Rohan D., Vanhaesebroeck, Bart, Meunier, Frédéric A., Taguchi, Tomohiko and Stow, Jennifer L. (2010). Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion. Journal of Cell Biology, 190 (6), 1053-1065. doi: 10.1083/jcb.201001028

Christ, Angelika N., Labzin, Larisa, Bourne, Gregory T., Fukunishi, Hirotada, Weber, Jane E., Sweet, Matthew J., Smythe, Mark L. and Flanagan, Jack U. (2010). Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthases. Journal of Medicinal Chemistry, 53 (15), 5536-5548. doi: 10.1021/jm100194a

Halili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363

Achard, Maud E. S., Tree, Jai J., Holden, James A., Simpfendorfer, Kim R., Wijburg, Odilia L. C., Strugnell, Richard A., Schembri, Mark A., Sweet, Matthew J., Jennings, Michael P. and McEwan, Alastair G. (2010). The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence. Infection and Immunity, 78 (5), 2312-2319. doi: 10.1128/IAI.01208-09

Ovchinnikov, Dmitry A., DeBats, Claire E. E., Sester, David P., Sweet, Matthew J. and Hume, David A. (2010). A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice. Journal of Leukocyte Biology, 87 (5), 815-822. doi: 10.1189/jlb.0809557

Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012

Summers, Kim M., Bokil, Nilesh J., Baisden, John M., West, Malcolm J., Sweet, Matthew J., Raggatt, Liza J. and Hume, David A. (2009). Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1. Genomics, 94 (4), 233-240. doi: 10.1016/j.ygeno.2009.06.005

Goh, Felicia, Irvine, Katharine M., Lovelace, Erica, Donnelly, Sheila, Jones, Malcolm K ., Brion, Kristian, Hume, David A., Kotze, Andrew C., Dalton John P., Ingham, Aaron and Sweet, Matthew J. (2009). Selective induction of the Notch ligand Jagged -1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signaling. Immunology, 127 (3), 326-337. doi: 10.1111/j.1365-2567.2008.02979.x

Suzuki, H, Forrest, ARR, van Nimwegen, E, Daub, CO, Balwierz, PJ, Irvine, KM, Lassmann, T, Ravasi, T, Hasegawa, Y, de Hoon, MJL, Katayama, S, Schroder, K, Carninci, P, Tomaru, Y, Kanamori-Katayama, M, Kubosaki, A, Akalin, A, Ando, Y, Arner, E, Asada, M, Asahara, H, Bailey, T, Bajic, VB, Bauer, D, Beckhouse, AG, Bertin, N, Bjorkegren, J, Brombacher, F, Bulger, E ... Riken Omics Science Center (2009). The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics, 41 (5), 553-562. doi: 10.1038/ng.375

Trieu, Angela, Bokil, Nilesh, Dunn, Jasmyn A., Roberts, Tara L., Xu, Damo, Liew, Foo Y., Hume, David A., Stacey, Katryn J. and Sweet, Matthew J. (2009). TLR-9-independent effects of inhibitory oligonucleotides on macrophages responses to S. typhimurium. Immunology and Cell Biology, 87 (3), 218-225. doi: 10.1038/icb.2008.95

Roberts, Tara L., Idris, Adi, Dunn, Jasmyn A., Kelly, Greg M., Burnton, Carol M., Hodgson, Samantha, Hardy, Lani. L., Garceau, Valerie, Sweet, Matthew J., Ross, Ian L., Hume, David A. and Stacey, Katryn J. (2009). HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science, 323 (5917), 1057-1060. doi: 10.1126/science.1169841

Halili, M. A., Andrews, M, Sweet, M. and Fairlie, D. P. (2009). Histone deacetylase inhibitors in inflammatory disease. Current Topics in Medicinal Chemistry, 9 (3), 309-319. doi: 10.2174/156802609788085250

Irvine, Katharine M., Andrews, Melanie R., Fernandez-Rojo, Manuel A., Schroder, Kate, Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Parton, Robert G., Hume, David A. and Sweet, Matthew J. (2009). Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. Journal of Leukocyte Biology, 85 (2), 278-288. doi: 10.1189/jlb.0808497

Achuthan, Adrian, Masendycz, Paul, Lopez, Jamie A., Nguyen, Thao, James, David E., Sweet, Matthew J., Hamilton, John A. and Scholz, Glen M. (2008). Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factpr 1 in macrophages. Molecular and Cellular Biology, 28 (20), 6149-6159. doi: 10.1128/MCB.00220-08

Lattin, Jane E., Schroder, Kate, Su, Andrew I., Walker, John R., Zhang, Jie, Wiltshire, Tim, Saijo, Kaoru, Glass, Christopher K., Hume, David A., Kellie, Stuart and Sweet, Matthew J. (2008). Expression analysis of G Protein-coupled receptors in mouse macrophages. Immunome Research, 4 (5) 5, 5. doi: 10.1186/1745-7580-4-5

Schroder, K., Spille, M., Pilz, A., Lattin, J., Bode, K. A., Irvine, K. M., Burrows, A. D., Ravasi, T., Weighardt, H., Stacey, K. J., Decker, T., Hume, D. A., Dalpke, A. H. and Sweet, M. J. (2007). Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages. Journal of Immunology, 179 (6), 3495-3503. doi: 10.4049/jimmunol.179.6.3495

Groom, JR, Fletcher, CA, Walters, SN, Grey, ST, Watt, SV, Sweet, MJ, Smyth, MJ, Mackay, CR and Mackay, F (2007). BAFF and MyD88 signals promote a lupuslike disease independent of T cells. Journal of Experimental Medicine, 204 (8), 1959-1971. doi: 10.1084/jem.20062567

Sweet, Matthew J., Mansell, Ashley and Wilson, Trevor J. (2007). The Australian toll-way gets the nod - meeting report of TLROZ 2007: pattern recognition receptors in immunity and disease, Melbourne, Australia, 16-18th May 2007. Immunology and Cell Biology, 85 (6), 401-403. doi: 10.1038/sj.icb.7100101

Lattin, J., Zidar, D., Schroder, K., Kellie, S., Hume, D. and Sweet, M. (2007). G-protein-coupled receptor expression, function, and signaling in macrophages. Journal of Leukocyte Biology, 82 (1), 16-32. doi: 10.1189/jlb.0107051

Schroder, Kate, Lichtinger, Monika, Irvine, Katharine M., Brion, Kristian, Trieu, Angela, Ross, Ian L., Ravasi, Timothy, Stacey, Katryn J., Rehli, Michael, Hume, David A. and Sweet, Matthew J. (2007). PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages. Journal of Leukocyte Biology, 81 (6), 1577-1590. doi: 10.1189/jlb.0107036

Ripoll, Vera M., Irvine, Katharine M., Ravasi, Timothy, Sweet, Matthew J. and Hume, David A. (2007). Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. Journal of Immunology, 178 (10), 6557-6566. doi: 10.4049/jimmunol.178.10.6557

Bode, K. A., Schroder, K., Hume, D. A., Ravasi, T., Heeg, K., Sweet, M. J. and Dalpke, A. H. (2007). Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology, 122 (4), 596-606. doi: 10.1111/j.1365-2567.2007.02678.x

Sester, D. P., Brion, K., Trieu, A., Goodridge, H. S., Roberts, T. L., Dunn, J., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2006). CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. Journal of Immunology, 177 (7), 4473-4480. doi: 10.4049/jimmunol.177.7.4473

Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2006). A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations. The FASEB Journal, 20 (11), 1921-1923. doi: 10.1096/fj.06-5848fje

Nilsson, Roland, Bajic, Vladimir B., Suzuki, Harukazu, di Bernardo, Diego, Bjorkegren, Johan, Katayama, Shintaro, Reid, James F., Sweet, Matthew J., Gariboldi, Manuela, Carninci, Piero, Hayashizaki, Yosihide, Hume, David A., Tegner, Jesper and Ravasi, Timothy (2006). Transcriptional network dynamics in macrophage activation. Genomics, 88 (2), 133-142. doi: 10.1016/j.ygeno.2006.03.022

Trieu, A., Roberts, T. L., Dunn, J. A., Sweet, M. J. and Stacey, K. J. (2006). DNA Motifs Suppressing TLR9 Responses. Critical reviews in Immunology, 26 (6), 527-544. doi: 10.1615/CritRevImmunol.v26.i6.50

Schroder, K., Sweet, M. J. and Hume, D. A. (2006). Signal integration between IFN gamma and TLR signalling pathways in macrophages. Immunobiology, 211 (6-8), 511-524. doi: 10.1016/j.imbio.2006.05.007

Aung, H. T., Schroder, K., Himes, S. R., Brion, K., van Zuylen, W., Trieu, A., Suzuki, H., Hayashizaki, Y., Hume, D. A., Sweet, M. J. and Ravasi, T. (2006). LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. Faseb Journal, 20 (9), 1315-1327. doi: 10.1096/fj.05-5360com

Roberts, T. L., Sweet, M. J., Hume, D. A. and Stacey, K. J. (2005). Cutting edge: Species-specific TLR9-mediated recognition of CpG and non-CpG phosphorothioate-modified ohgonucleotides. Journal of Immunology, 174 (2), 605-608. doi: 10.4049/jimmunol.174.2.605

Sester, D. P., Trieu, A., Brion, K., Schroder, K., Ravasi, T., Robinson, J. A., McDonald, R. C., Ripoll, V., Wells, C. A., Suzuki, H., Hayashizaki, Y., Stacey, K. J., Hume, D. A. and Sweet, M. J. (2005). LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action. Immunobiology, 210 (2-4), 97-107. doi: 10.1016/j.imbio.2005.05.004

Roberts, T. L., Dunn, J. A., Terry, T. D., Jennings, M. P., Hume, D. A., Sweet, M. J. and Stacey, K. J. (2005). Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides. Journal of Immunology, 175 (6), 3569-3576. doi: 10.4049/jimmunol.175.6.3569

Trajkovic, Vladimir, Sweet, Matthew J. and Xu, Damo M. (2004). T1/ST2 - an IL-1 receptor-like modulator of immune responses. Cytokine & Growth Factor Reviews, 15 (2-3), 87-95. doi: 10.1016/j.cytogfr.2004.02.004

Wells, C. A., Ravasi, T., Faulkner, G. J., Carninci, P., Okazaki, Y., Hayashizaki, Y., Sweet, M.J., Wainwright, B. J. and Hume, D. A. (2003). Genetic control of the innate immune response. BMC Immunology, 4 (Article 5) 5, 1-18. doi: 10.1186/1471-2172-4-5

Stacey, Katryn J., Young, Greg R., Clark, Francis, Sester, David P., Roberts, Tara L., Naik, Shalin, Sweet, Matthew J. and Hume, David A. (2003). The molecular basis for the lack of immunostimulatory activity of vertebrate DNA. Journal of Immunology, 170 (7), 3614-3620. doi: 10.4049/jimmunol.170.7.3614

Sweet, MJ and Hume, DA (2003). CSF-1 as a regulator of macrophage activation and immune responses. Archivum Immunologiae Et Therapiae Experimentalis, 51 (3), 169-177.

Sweet, Matthew J., Campbell, Carol C., Sester, David P., Xu, Damo, McDonald, Rebecca C., Stacey, Katryn J., Hume, David A. and Liew, Foo Y. (2002). Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. Journal of Immunology, 168 (1), 392-399. doi: 10.4049/jimmunol.168.1.392

Hume, D. A., Underhill, D. M., Sweet, M. J., Ozinsky, A.O., Liew, F.Y. and Aderem, A. (2001). Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state. BMC Immunology, 2 (11) 11, 1-12. doi: 10.1186/1471-2172-2-11

Carter, R. W., Sweet, M. J., Xu, D. M., Klemenz, R., Liew, F. Y. and Chan, W. L. (2001). Regulation of ST2L expression on T helper (Th) type 2 cells. European Journal of Immunology, 31 (10), 2979-2985. doi: 10.1002/1521-4141(2001010)31:10<2979::AID-IMMU2979>3.0.CO;2-B

Sweet, M. J., Leung, B. P., Kang, D. W., Sogaard, M., Schulz, K., Trajkovic, V., Campbell, C. C., Xu, D. M. and Liew, F. Y. (2001). A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of toll-like receptor 4 expression. Journal of Immunology, 166 (11), 6633-6639. doi: 10.4049/jimmunol.166.11.6633

Stacey, K. J., Sester, D. P., Sweet, M. J. and Hume, D. A. (2000). Macrophage activation by immunostimulatory DNA. Current Topics in Microbiology and Immunology, 247, 41-58. doi: 10.1007/978-3-642-59672-8_3

Wei, X.Q., Leung, B.P., Niedbala, W., Piedrafita, D., Feng, G.J., Sweet, M., Dobbie, L., Smith, A.J. and Liew F.Y. (1999). Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice. Journal of Immunology, 163 (5), 2821-2828.

Kakuda, D. K., Sweet, M. J., MacLeod, C. L., Hume, D. A. and Markovich, D. (1999). CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages. Biochemical Journal, 340 (2), 549-553. doi: 10.1042/0264-6021:3400549

Sester, D. P., Beasley, S. J., Sweet, M. J., Fowles, L. F., Cronau, S., Stacey, K. J. and Hume, D. A. (1999). Bacterial/CpG DNA down-modulates colony stimulating factor-1 receptor surface expression on murine bone marrow-derived macrophages with concomitant growth arrest and factor-independent survival. Journal of Immunology, 163 (12), 6541-6550.

Sester, D. P., Stacey, K. J., Sweet, M. J., Beasley, S. J., Cronau, S. L. and Hume, D. A. (1999). The actions of bacterial DNA on murine macrophages. Journal of Leukocyte Biology, 66 (4), 542-548. doi: 10.1002/jlb.66.4.542

Sweet, M. J., Stacey, K. J., Kakuda, D. K., Markovich, D. and Hume, D. A. (1998). IFN-γ primes macrophage responses to bacterial DNA. Journal of Interferon and Cytokine Research, 18 (4), 263-271. doi: 10.1089/jir.1998.18.263

Sweet, M. J., Stacey, K. J., Ross, I. L., Ostrowski, M. C. and Hume, D. A. (1998). Involvement of Ets, rel and Sp1-like proteins in lipopolysaccharide-mediated activation of the HIV-1 LTR in macrophage. Journal of Inflammation, 48 (2), 67-83.

Sweet, M. J. and Hume, D. A. (1996). Endotoxin signal transduction in macrophages. Journal of Leukocyte Biology, 60 (1), 8-26. doi: 10.1002/jlb.60.1.8

Stacey, K. J., Sweet, M. J. and Hume, D. A. (1996). Macrophages ingest and are activated by bacterial DNA. Journal of Immunology, 157 (5), 2116-2122.

Sweet, M. J. and Hume, D. A. (1996). Bacterial lipopolysaccharide confers resistance to G418, doxorubicin and taxol in the murine macrophage cell line, RAW264. Journal of Leukocyte Biology, 59 (2), 280-286. doi: 10.1002/jlb.59.2.280

Sweet, M. J. and Hume, D. A. (1995). RAW264 macrophages stably transfected with an HIV-1-LTR reporter gene provide a sensitive bioassay for analysis of signalling pathways in macrophages stimulated with lipopolysaccharide, TNF-α or taxol. Journal of Inflammation, 45 (2), 126-135.

Reddy, M. A., Yang, B. S., Yue, X., Barnett, C. J., Ross, I. L., Sweet, M. J., Hume, D. A. and Ostrowski, M. C. (1994). Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. Journal of Experimental Medicine, 180 (6), 2309-2319. doi: 10.1084/jem.180.6.2309

Murphy, K. M., Sweet, M. J. and Hume, D. A. (1994). The HIV-1 regulatory protein Nef has a specific function in a murine macrophage cell line. Journal of Leukocyte Biology, 56 (3), 294-303. doi: 10.1002/jlb.56.3.294

Murphy, Kathleen M., Sweet, Matthew J., Ross, Ian L. and Hume, David A. (1993). Effects of the tat and nef gene products of human immunodeficiency virus type 1 (HIV-1) on transcription controlled by the HIV-1 long terminal repeat and on cell growth in macrophages. Journal of Virology, 67 (12), 6956-6964. doi: 10.1128/jvi.67.12.6956-6964.1993

Haq, Sabah, Smith, Deandra R., von Pein, Jessica B., Sweet, Matthew J. and Knoell, Daren L. (2023). ZIP8 impacts protease activity in macrophages in response to Streptococcus pneumoniae. Immunology 2023 Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.162.03

Iyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY.

Ramnath, D., Irvine, K., Lukowski, S., Horsfall, L., Loh, K., Clouston, A., Patel, P., Iyer, A., Lampe, G., Stow, J., Schroder, K., Fairlie, D., Powell, J., Powell, E. and Sweet, M. (2018). RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease. International Liver Congress (ILC), Paris, France, 11-15 April, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(18)31040-7

Stocks, C. J., Kapetanovic, R., Bokil, N., Phan, M. -D, Lo, A., Schembri, M. and Sweet, M. J. (2016). The role of zinc in macrophage antimicrobial responses. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Luo, L., Bokil, N., Lansdaal, N., Wall, A., Marceline, F., Guo, Z., Alexandrov, K., Ross, I, Hibbs, M., Stow, J. and Sweet, M. (2016). A new Toll-like receptor adaptor protein that provides specificity to inflammatory cytokine production from macrophages. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. HOBOKEN: Wiley-Blackwell.

Chen, K., Gross, C., Wall, A., Stacey, K., Stow, J., Sweet, M. and Schroder, K. (2016). Inflammatory response sculpting by neutrophil inflammasomes. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Sweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Oxford, United Kingdom: Wiley-Blackwell. doi: 10.1111/imm.12002

Irvine, Katharine M., Andrews, Melanie R., Fernandez, Manuel A., Parton, Robert G., Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Hume, David A. and Sweet, M. J. (2008). The identification of novel CSF-1 target genes in human macrophages. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, Montreal Canada, Oct 12-16, 2008. LONDON: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD. doi: 10.1016/j.cyto.2008.07.078

Van Zuiiien, Wim, Schroder, K, Garceau, V, Sweet, MJ, Kellie, S and Hume, DA (2008). Expression and function of Schlafen-4 in macrophage biology and inflammation. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, Montreal Canada, Oct 12-16, 2008. LONDON: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD. doi: 10.1016/j.cyto.2008.07.081

Sweet, Matthew J., Mansell, Ashley and Wilson, Trevor J. (2007). The Australian Toll-way gets the Nod - Meeting report of TLROZ 2007: Pattern recognition receptors in immunity and disease, Melbourne, Australia, 16-18th May 2007. doi: 10.1038/sj.icb.7100101

Schroder, Kate, Irvine, Katharine M., Biron, Kristian, Lichtinger, Monika, Ravasi, Timothy, Rehli, Michael, Sweet, Matthen J. and Hume, David A. (2005). PU.1 and ICSBP regulate the tlr9 promoter in mouse macrophages. BASEL: BIRKHAUSER VERLAG AG.

Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Bu, Xiangyong, Harte, Michael F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2005). A potent CSF-1 Receptor tyrosine kinase inhibitor targets survival and effector functions in marine macrophage populations. BASEL: BIRKHAUSER VERLAG AG.

Lattin, Jane E., Blomberg, Lovisa M., Daly, Norelle L., Craik, David J., Robinson, Jodie A., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2005). Beta-arrestin expression and function in macrophages. 7th World Congress on Inflammation: Inflammation 2005: Inflammation, the Key to much pathology, Melbourne, Australia, 20 - 24 August 2005. Basel, Switzerland: Birkhaeuser.

Sweet, Matthew J., Schroder, Kate, Sester, David P., Trieu, Angela, Rehli, Michael, Risvanathan, Kumar, Stacey, Katryn J. and Hume, David A. (2005). Regulation and function of toll-like receptor 9 in macrophages. 7th World Congress on Inflammation, Melbourne, VIC Australia, 20-24 August 2005. Switzerland: Birkhaeuser Science.

Trieu, Angela, Cronau, Steve, Roberts, Tara, Lottin, Jane, Vlahos, Ross, Stacey, Katryn J., Hume, David A. and Sweet, Matthew J. (2005). Blockade of CSF-1 action enhances CpG DNA responses in vivo. 7th World Congress on Inflammation, Melbourne, Australia, 20-24 August 2005. Switzerland: Birkhaeuser Science.

Roberts, Tara L., Dann, Jasmyn A., Sweet, Matthew J., Hume, David A., Lenert, Petar and Stacey, Katryn J. (2005). Purified splenic B-cells do not respond to E. coli DNA. 7th World Congress on Inflammation, Melbourne, Australia, 20-24 August 2005. Switzerland: Birkhaeuser Science.

Stacey, K. J., Sester, D. P., Murphy, K. M., Sweet, M. J. and Hume, D. A. (2000). Replication protein A binds preferentially to immunostimulatory oligonucleotides.. -, -, -. Bethesda, MD United States: Federation of American Societies for Experimental Biology.

Sester, D. P., Sweet, M. J., Stacey, K. J. and Hume, D. A. (1999). Immunostimulatory DNA promotes factor independent survival of macrophages. ComBio 99, Conrad Jupiters, Gold Coast, 27-30 September, 1999. Kent Town, SA: Australian Society for Biochemistry & Molecular Biology.

Sester, D. P., Beasley, S. J., Sweet, M. J., Stacey, K. J. and Hume, D. A. (1999). CpG DNA effects macrophage CSF-1 receptor cell surface expression, proliferation and survival. 15th International Congress for Society for Leukocyte Biology, Churchill College, Cambridge UK, 22-26 September, 1999. Bethesda, Maryland: Society for Leukocyte Biology.

Stacey, K. J., Sweet, M. and Hume, D. A. (1996). Activation of macrophages by bacterial DNA. -, -, -. Oxford, United Kingdom: John Wiley & Sons .

Professor Matt Sweet

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