Dr Laura Fenlon
NHMRC Leadership Fellow
School of Biomedical Sciences Faculty of Medicine
| Featured projects | Duration |
|---|---|
|
RNA velocity quantification of single-cell transcriptomics Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2021 |
Publications
Journal Articles
Bhembre, Nishita, Paolino, Annalisa, Das, Sooraj S., Guntupalli, Sumasri, Fenlon, Laura R. and Anggono, Victor (2024). Learning-induced remodelling of inhibitory synapses in the motor cortex. Open Biology, 14 (11) 240109, 1-9. doi: 10.1098/rsob.240109
Currey, Laura, Mitchell, Benjamin, Al-Khalily, Majd, McElnea, Sarah-Jayne, Kozulin, Peter, Harkins, Danyon, Pelenyi, Alexandra, Fenlon, Laura, Suarez, Rodrigo, Kurniawan, Nyoman D, Burne, Thomas H, Harris, Lachlan, Thor, Stefan and Piper, Michael (2024). Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development. Cerebral Cortex, 34 (7) ARTN bhae268. doi: 10.1093/cercor/bhae268
Bodea, Gabriela O., Botto, Juan M., Ferreiro, Maria E., Sanchez-Luque, Francisco J., de los Rios Barreda, Jose, Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Jansz, Natasha, Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Da Costa Guevara, Darwin J., Cumner, Linda, Bell, Charles C., Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H. C., Love, Chloe J., Saha, Karabi, Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2024). LINE-1 retrotransposons contribute to mouse PV interneuron development. Nature Neuroscience, 27 (7), 1-34. doi: 10.1038/s41593-024-01650-2
Lynton, Zorana, Suárez, Rodrigo and Fenlon, Laura R. (2023). Brain plasticity following corpus callosum agenesis or loss: a review of the Probst bundles. Frontiers in Neuroanatomy, 17 1296779, 1-18. doi: 10.3389/fnana.2023.1296779
Paolino, Annalisa, Haines, Elizabeth H., Bailey, Evan J., Black, Dylan A., Moey, Ching, García-Moreno, Fernando, Richards, Linda J., Suárez, Rodrigo and Fenlon, Laura R. (2023). Non-uniform temporal scaling of developmental processes in the mammalian cortex. Nature Communications, 14 (1) 5950, 1-17. doi: 10.1038/s41467-023-41652-5
Haines, Elizabeth, Bailey, Evan, Nelson, John, Fenlon, Laura R. and Suárez, Rodrigo (2023). Clade-specific forebrain cytoarchitectures of the extinct Tasmanian tiger. Proceedings of the National Academy of Sciences, 120 (32) e2306516120, e2306516120. doi: 10.1073/pnas.2306516120
Suárez, Rodrigo, Bluett, Tobias, McCullough, Michael H., Avitan, Lilach, Black, Dylan A., Paolino, Annalisa, Fenlon, Laura R., Goodhill, Geoffrey J. and Richards, Linda J. (2023). Cortical activity emerges in region-specific patterns during early brain development. Proceedings of the National Academy of Sciences, 120 (22) e2208654120, e2208654120. doi: 10.1073/pnas.2208654120
Kozulin, Peter, Zhao, Qiong-Yi, Richards, Linda, Fenlon, Laura and Suárez, Rodrigo (2022). The people behind the papers - Peter Kozulin, Rodrigo Suárez, Qiong-Yi Zhao, Linda Richards and Laura Fenlon. Development, 149 (3) dev200543. doi: 10.1242/dev.200543
Kozulin, Peter, Suárez, Rodrigo, Zhao, Qiong-Yi, Paolino, Annalisa, Richards, Linda J. and Fenlon, Laura R. (2022). Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes. Development, 149 (3) dev200212. doi: 10.1242/dev.200212
Fenlon, Laura R (2021). Timing as a mechanism of development and evolution in the cerebral cortex. Brain, behavior and evolution, 97 (1/2), 8-32. doi: 10.1159/000521678
Fenlon, Laura R., Suarez, Rodrigo, Lynton, Zorana and Richards, Linda J. (2021). The evolution, formation and connectivity of the anterior commissure. Seminars in Cell and Developmental Biology, 118, 50-59. doi: 10.1016/j.semcdb.2021.04.009
Morcom, Laura, Gobius, Ilan, Marsh, Ashley P. L., Suárez, Rodrigo, Lim, Jonathan W. C., Bridges, Caitlin, Ye, Yunan, Fenlon, Laura R., Zagar, Yvrick, Douglass, Amelia M., Donahoo, Amber-Lee, Fothergill, Thomas, Shaikh, Samreen, Kozulin, Peter, Edwards, Timothy J., Cooper, Helen M., IRC5 Consortium, Sherr, Elliott H., Chédotal, Alain, Leventer, Richard J., Lockhart, Paul J. and Richards, Linda J. (2021). DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. eLife, 10 e61769, 1-35. doi: 10.7554/eLife.61769
Edwards, Timothy J., Fenlon, Laura R., Dean, Ryan J., Bunt, Jens, Sherr, Elliott H. and Richards, Linda J. (2020). Altered structural connectivity networks in a mouse model of complete and partial dysgenesis of the corpus callosum. NeuroImage, 217 116868, 116868. doi: 10.1016/j.neuroimage.2020.116868
Paolino, Annalisa, Fenlon, Laura R., Kozulin, Peter, Haines, Elizabeth, Lim, Jonathan W. C., Richards, Linda J. and Suárez, Rodrigo (2020). Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution. Proceedings of the National Academy of Sciences, 117 (19), 201922422-10564. doi: 10.1073/pnas.1922422117
Paolino, Annalisa, Fenlon, Laura R., Suárez, Rodrigo and Richards, Linda J. (2018). Transcriptional control of long-range cortical projections. Current Opinion in Neurobiology, 53, 57-65. doi: 10.1016/j.conb.2018.05.005
Suárez, Rodrigo, Paolino, Annalisa, Fenlon, Laura R., Morcom, Laura R., Kozulin, Peter, Kurniawan, Nyoman D. and Richards, Linda J. (2018). A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum. Proceedings of the National Academy of Sciences, 115 (38), 9622-9627. doi: 10.1073/pnas.1808262115
Paolino, Annalisa, Fenlon, Laura R., Kozulin, Peter, Richards, Linda J. and Suarez, Rodrigo (2018). Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development. Journal of Neuroscience Methods, 293, 45-52. doi: 10.1016/j.jneumeth.2017.09.004
Mitew, Stanislaw, Gobius, Ilan, Fenlon, Laura R., McDougall, Stuart J., Hawkes, David, Xing, Yao Lulu, Bujalka, Helena, Gundlach, Andrew L., Richards, Linda J., Kilpatrick, Trevor J., Merson, Tobias D. and Emery, Ben (2018). Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner. Nature Communications, 9 (1) 306, 306. doi: 10.1038/s41467-017-02719-2
Suarez, Rodrigo, Paolino, Annalisa, Kozulin, Peter, Fenlon, Laura R., Morcom, Laura R., Englebright, Robert, O'Hara, Patricia J., Murray, Peter J. and Richards, Linda J. (2017). Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation. Plos One, 12 (9) e0184450, 1-18. doi: 10.1371/journal.pone.0184450
Fenlon, Laura R., Suarez, Rodrigo and Richards, Linda J. (2017). The anatomy, organisation and development of contralateral callosal projections of the mouse somatosensory cortex. Brain and Neuroscience Advances, 1, 239821281769488. doi: 10.1177/2398212817694888
Lim, Jonathan W. C., Donahoo, Amber-Lee S., Bunt, Jens, Edwards, Timothy J., Fenlon, Laura R., Liu, Ying, Zhou, Jing, Moldrich, Randal X., Piper, Michael, Gobius, Ilan, Bailey, Timothy L., Wray, Naomi R., Kessaris, Nicoletta, Poo, Mu-Ming, Rubenstein, John L. R. and Richards, Linda J. (2015). EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex. Development, 142 (21), 3746-3757. doi: 10.1242/dev.119909
Fenlon, Laura R., Liu, Sha, Gobius, Ilan, Kurniawan, Nyoman D., Murphy, Skyle, Moldrich, Randal X. and Richards, Linda J. (2015). Formation of functional areas in the cerebral cortex is disrupted in a mouse model of autism spectrum disorder. Neural Development, 10 (10) 10, 1-14. doi: 10.1186/s13064-015-0033-y
Fenlon, Laura R. and Richards, Linda J. (2015). Contralateral targeting of the corpus callosum in normal and pathological brain function. Trends in Neurosciences, 38 (5), 264-272. doi: 10.1016/j.tins.2015.02.007
Suarez, Rodrigo, Fenlon, Laura R., Marek, Roger, Avitan, Lilach A, Sah, Pankaj, Goodhill, Geoffrey J. and Richards, Linda J. (2014). Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum. Neuron, 82 (6), 1289-1298. doi: 10.1016/j.neuron.2014.04.040
Fenlon, Laura R. and Suarez, Rodrigo (2013). Thalamic afferents and neocortical arealization: An ongoing journey. Journal of Neuroscience, 33 (35), 13938-13939. doi: 10.1523/JNEUROSCI.2859-13.2013
Kamke, Marc R., Hall, Michelle G., Lye, Hayley F., Sale, Martin V., Fenlon, Laura R., Carroll, Timothy J., Riek, Stephen and Mattingley, Jason B. (2012). Visual attentional load influences plasticity in the human motor cortex. Journal of Neuroscience, 32 (20), 7001-7008. doi: 10.1523/JNEUROSCI.1028-12.2012
Conference Papers
Emery, B., Mitew, S., Gobius, I., Fenlon, L. R., McDougall, S., Hawkes, D., Xing, Y. Lulu, Bujalka, H., Gundlach, A. L., Richards, L. J., Kilpatrick, T. J., Merson, T. and Foster, A. (2019). Oligodendroglial responses to neuronal activity in the developing and adult CNS. 14th European Meeting on Glial Cells in Health and Disease (GLIA), Porto, Portugal, 10-13 July 2019. Hoboken, NJ USA: John Wiley & Sons.
Emery, B., Mitew, S., Gobius, I., Fenlon, L., McDougall, S., Hawkes, D., Xing, L., Bujalka, H., Gundlach, A., Richards, L., Kilpatrick, T. and Merson, T. (2017). The regulation of CNS myelination by neuronal activity. ISN-ESN Meeting, Paris, France, 20-24 August 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.14089
Suarez, R., Paolino, A., Kozulin, P., Morcom, L., Fenlon, L. and Richards, L. (2015). Developmental scenarios for the evolutionary origin of the corpus callosum. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188
Fenlon, L., Suarez, R. and Richards, L. (2015). The organisation, development and connectivity of two callosal projections arising from the mouse somatosensory cortex. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188
Preprint
Bodea, Gabriela O., Ferreiro, Maria E., Sanchez-Luque, Francisco J., Botto, Juan M., Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H.C., Love, Chloe J., Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2022). LINE-1 retrotransposon activation intrinsic to interneuron development.
Thesis
Fenlon, Laura (2017). Contralateral targeting of the corpus callosum. PhD Thesis, Queensland Brain Institute, The University of Queensland. doi: 10.14264/uql.2017.753
Data Collections
Suarez, Rodrigo, Bluett, Tobias, McCullough, Michael, Avitan, Lilach, Paolino, Annalisa, Fenlon, Laura, Goodhill, Geoffrey and Richards, Linda (2023). Raw data for "Cortical activity emerges in region-specific patterns during early brain development. Suárez et al., PNAS 2023". The University of Queensland. (Dataset) doi: 10.48610/5ccfb47
Fenlon, Laura (2020). Marsupial neurogenesis and neuroanatomy. The University of Queensland. (Dataset) doi: 10.48610/c8578ab