Dr Mitchell Stark

Featured projects	Duration
Developing new "spatial omics" capabilities Genome Innovation Hub Collaborative Project (UQ infrastructure)	2021

Stark, Mitchell S. and Bonazzi, Vanessa F. (2017). Gene expression array analysis to identify candidate tumor suppressor genes in melanoma. Methods in Molecular Biology. (pp. 1-17) New York, NY, United States: Springer. doi: 10.1007/7651_2017_54

Sturm, Richard A., Smit, Darren J., Duffy, David L., McLean, Catriona, Scolyer, Richard A., McArthur, Grant A., Papenfuss, Anthony T., Stark, Mitchell S., Soyer, H. Peter and Mar, Victoria J. (2024). Uncovering molecular mechanisms for amelanotic/hypopigmented primary cutaneous melanoma. British Journal of Dermatology ljae336. doi: 10.1093/bjd/ljae336

Kao, Yung-Ching and Stark, Mitchell S (2024). Challenging the lymph node progression model of melanoma. The Journal of Investigative Dermatology, 144 (11), 2344-2346. doi: 10.1016/j.jid.2024.04.021

Maas, Ellie J., DeBortoli, Emily, Nathan, Vaishnavi, Freeman, Ned P., Mothershaw, Adam, Smit, Darren J., Betz-Stablein, Brigid, Aoude, Lauren G., Stark, Mitchell S., Sturm, Richard A., Soyer, H. Peter and McInerney-Leo, Aideen M. (2024). POT1 and multiple primary melanomas: the dermatological phenotype. Journal of Medical Genetics, 61 (9) jmg-2023-109637, 1-4. doi: 10.1136/jmg-2023-109637

Hossain, Akbor, Tom, Lisa N., Melati‐Rad, Ala, Yamada, Miko, Hammerlindl, Sabrina, Jagirdar, Kasturee, Prow, Tarl W., Soyer, H. Peter and Stark, Mitchell S. (2024). MicroRNA expression profiling of cutaneous squamous cell carcinomas and precursor lesions. Skin Health and Disease, 4 (3) e360, e360. doi: 10.1002/ski2.360

Qi, X., Bertling, K., Torniainen, J., Kong, F., Gillespie, T., Primiero, C., Stark, M. S., Dean, P., Indjin, D., Li, L. H., Linfield, E. H., Davies, A. G., Brünig, M., Mills, T., Rosendahl, C., Soyer, H. P. and Rakić, A. D. (2024). Terahertz in vivo imaging of human skin: toward detection of abnormal skin pathologies. APL Bioengineering, 8 (1) 016117. doi: 10.1063/5.0190573

Stark, Mitchell S., Sturm, Richard A., Pan, Yan, Smit, Darren J., Kommajosyula, Varsha, Lee, Katie J., Jagirdar, Kasturee, McLean, Catriona, Duffy, David L., Soyer, H. Peter and Mar, Victoria J. (2024). Assessing the genetic risk of nodular melanoma using a candidate gene approach. British Journal of Dermatology, 190 (2), 199-206. doi: 10.1093/bjd/ljad365

Lee, Katie J., Soyer, H. Peter and Stark, Mitchell S. (2023). The skin molecular ecosystem holds the key to nevogenesis and melanomagenesis. The Journal of Investigative Dermatology, 144 (3), 456-465. doi: 10.1016/j.jid.2023.09.271

Stark, Mitchell S., Harris, Teresa, Grossman, Douglas and Judson-Torres, Robert (2023). BRAF variant allele fraction-A predictor of response to targeted therapy?. Journal of the European Academy of Dermatology and Venereology., 37 (10), 1945-1946. doi: 10.1111/jdv.19389

Vergara, Ismael A. and Stark, Mitchell S. (2023). One step closer to improving melanoma diagnosis and prognosis with liquid biopsies. British Journal of Dermatology, 189 (3) ARTN ljad185, 255-256. doi: 10.1093/bjd/ljad185

Maas, Ellie J., Wallingford, Courtney K., DeBortoli, Emily, Smit, Darren J., Betz-Stablein, Brigid, Aoude, Lauren G., Stark, Mitchell S., Sturm, Richard A., Soyer, H. Peter and McInerney-Leo, Aideen M. (2023). GOLM1: expanding our understanding of melanoma susceptibility. Journal of Medical Genetics, 60 (9) jmg-2023-109348, 1-3. doi: 10.1136/jmg-2023-109348

Jayasinghe, Dilki, Betz-Stablein, Brigid, Stark, Mitchell S., Soyer, H. Peter and Janda, Monika (2023). Spatial Randomness in the distribution of acquired melanocytic naevi of the back in a population-based sample. The Journal of Investigative Dermatology, 143 (6), 1108-1111.e3. doi: 10.1016/j.jid.2022.11.013

Muse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. Journal of Investigative Dermatology, 143 (9), 1830-1834. doi: 10.1016/j.jid.2023.03.1653

Qi, Xiaoqiong, Bertling, Karl, Stark, Mitchell S., Taimre, Thomas, Kao, Yung-Ching, Lim, Yah Leng, Han, She, O'Brien, Blake, Collins, Angus, Walsh, Michael, Torniainen, Jari, Gillespie, Timothy, Donose, Bogdan C., Dean, Paul, Li, Lian He, Linfield, Edmund H., Davies, A. Giles, Indjin, Dragan, Soyer, H. Peter and Rakic, Aleksandar D. (2023). Terahertz imaging of human skin pathologies using laser feedback interferometry with quantum cascade lasers. Biomedical Optics Express, 14 (4) ARTN 480615, 1393-1410. doi: 10.1364/boe.480615

Stark, Mitchell S. (2023). Deficiencies in mismatch DNA repair: providing the soil for large-to-giant congenital melanocytic naevus development. The British journal of dermatology, 188 (1) ARTN ljac037, 5-5. doi: 10.1093/bjd/ljac037

Muse, Meghan E., Bergman, Drew T., Salas, Lucas A., Tom, Lisa N., Tan, Jean-Marie, Laino, Antonia, Lambie, Duncan, Sturm, Richard A., Schaider, Helmut, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2022). Genome-scale DNA methylation analysis identifies repeat element alterations that modulate the genomic stability of melanocytic nevi. The Journal of Investigative Dermatology, 142 (7), 1893-1902.e7. doi: 10.1016/j.jid.2021.11.025

Huang, Nancy, Lee, Katie J. and Stark, Mitchell S. (2022). Current trends in circulating biomarkers for melanoma detection. Frontiers in Medicine, 9 873728, 873728. doi: 10.3389/fmed.2022.873728

Lee, Katie J. and Stark, Mitchell S. (2022). In Vivo Melanoma Cell Morphology and Tumor Aggressiveness: The Promise of Reflectance Confocal Microscopy in Reducing Unnecessary Excisions. Journal of Investigative Dermatology, 142 (8), 2053-2054. doi: 10.1016/j.jid.2022.01.011

Lee, Katie J., Betz-Stablein, Brigid, Stark, Mitchell S., Janda, Monika, McInerney-Leo, Aideen M., Caffery, Liam J., Gillespie, Nicole, Yanes, Tatiane and Soyer, H. Peter (2022). The future of precision prevention for advanced melanoma. Frontiers in Medicine, 8 818096, 818096. doi: 10.3389/fmed.2021.818096

Wang, Jing, Kao, Yung‐Ching, Zhou, Quan, Wuethrich, Alain, Stark, Mitchell S., Schaider, Helmut, Soyer, H. Peter, Lin, Lynlee L. and Trau, Matt (2021). An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas. Advanced Functional Materials, 32 (3) 2010296, 1-9. doi: 10.1002/adfm.202010296

Giblin, William, Bringman-Rodenbarger, Lauren, Guo, Angela H., Kumar, Surinder, Monovich, Alexander C., Mostafa, Ahmed M., Skinner, Mary E., Azar, Michelle, Mady, Ahmed S.A., Chung, Carolina H., Kadambi, Namrata, Melong, Keith-Allen, Lee, Ho-Joon, Zhang, Li, Sajjakulnukit, Peter, Trefely, Sophie, Varner, Erika L., Iyer, Sowmya, Wang, Min, Wilmott, James S., Soyer, H. Peter, Sturm, Richard A., Pritchard, Antonia L., Andea, Aleodor A., Scolyer, Richard A., Stark, Mitchell S., Scott, David A., Fullen, Douglas R., Bosenberg, Marcus W. ... Lombard, David B. (2021). The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. Journal of Clinical Investigation, 131 (12) e138926, 1-19. doi: 10.1172/jci138926

Kan, Chin Fung Kelvin, Unis, Graham D., Li, Luke Z., Gunn, Susan, Li, Li, Soyer, H. Peter and Stark, Mitchell S. (2021). Circulating biomarkers for early stage non-small cell lung carcinoma detection: supplementation to low‐dose computed tomography. Frontiers in Oncology, 11 555331, 555331. doi: 10.3389/fonc.2021.555331

Fuiten, Allison M., Fankhauser, Reilly G., Smit, Darren J., Stark, Mitchell S., Enright, Trevor F., Wood, Mary A., DePatie, Nicholas A., Pivik, Karla, Sturm, Richard A., Berry, Elizabeth G. and Kulkarni, Rajan P. (2021). Genetic analysis of multiple primary melanomas arising within the boundaries of congenital nevi depigmentosa. Pigment Cell & Melanoma Research, 34 (6) pcmr.12979, 1123-1130. doi: 10.1111/pcmr.12979

Stark, Mitchell S., Tell-Martí, Gemma, Martins da Silva, Vanessa, Martinez-Barrios, Estefania, Calbet-Llopart, Neus, Vicente, Asunción, Sturm, Richard A., Soyer, H. Peter, Puig, Susana, Malvehy, Josep, Carrera, Cristina and Puig-Butillé, Joan A. (2021). The distinctive genomic landscape of giant congenital melanocytic nevi. Journal of Investigative Dermatology, 141 (3), 692-695. doi: 10.1016/j.jid.2020.07.022

Lee, Katie J., Janda, Monika, Stark, Mitchell S, Sturm, Richard A. and Soyer, H. Peter (2021). On naevi and melanomas: two sides of the same coin?. Frontiers in Medicine, 8 635316, 635316. doi: 10.3389/fmed.2021.635316

Emmett, S.E., Stark, M.S., Pandeya, N., Panizza, B., Whiteman, D.C. and Antonsson, A. (2021). MicroRNA expression is associated with human papillomavirus status and prognosis in mucosal head and neck squamous cell carcinomas. Oral Oncology, 113 105136, 105136. doi: 10.1016/j.oraloncology.2020.105136

McMeniman, E. K., McInerney-Leo, A. M., Peach, E., Lee, K. J., Yanes, T., Jagirdar, K., Stark, M. S., Soyer, H. P., Duffy, D. L. and Sturm, R. A. (2020). CDKN2A testing threshold in a high-risk Australian melanoma cohort: number of primaries, family history and young age of onset impact risk. Journal of the European Academy of Dermatology and Venereology, 34 (12) jdv.16627, e797-e798. doi: 10.1111/jdv.16627

Stark, Mitchell S., Denisova, Evgeniya, Kays, Trent A., Heidenreich, Barbara, Rachakonda, Sivaramakrishna, Requena, Celia, Sturm, Richard A., Soyer, H. Peter, Nagore, Eduardo and Kumar, Rajiv (2020). Mutation signatures in melanocytic nevi reveal characteristics of defective DNA repair. Journal of Investigative Dermatology, 140 (10), 2093-2096.e2. doi: 10.1016/j.jid.2020.02.021

Rayner, Jenna E., Duffy, David L., Smit, Darren J., Jagirdar, Kasturee, Lee, Katie J., De’Ambrosis, Brian, Smithers, B. Mark, McMeniman, Erin K., McInerney-Leo, Aideen M., Schaider, Helmut, Stark, Mitchell S., Soyer, H. Peter and Sturm, Richard A. (2020). Germline and somatic albinism variants in amelanotic/hypomelanotic melanoma: increased carriage of TYR and OCA2 variants. PLoS ONE, 15 (9) e0238529, e0238529. doi: 10.1371/journal.pone.0238529

Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702

Pavey, Sandra, Pinder, Alex, Fernando, Winnie, D'Arcy, Nicholas, Matigian, Nicholas, Skalamera, Dubravka, Lê Cao, Kim-Anh, Loo-Oey, Dorothy, Hill, Michelle M., Stark, Mitchell, Kimlin, Michael, Burgess, Andrew, Cloonan, Nicole, Sturm, Richard A. and Gabrielli, Brian (2019). Multiple interaction nodes define the post-replication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load. Molecular Oncology, 14 (1) 1878-0261.12601, 22-41. doi: 10.1002/1878-0261.12601

Stark, Mitchell S., Gray, Elin S., Isaacs, Timothy, Chen, Fred K., Millward, Michael, McEvoy, Ashleigh, Zaenker, Pauline, Ziman, Melanie, Soyer, H. Peter, Glasson, William J., Warrier, Sunil K., Stark, Andrew L., Rolfe, Olivia J., Palmer, Jane M. and Hayward, Nicholas K. (2019). A panel of circulating microRNAs detects uveal melanoma with high precision. Translational Vision Science and Technology, 8 (6) 12, 12-12. doi: 10.1167/tvst.8.6.12

Duffy, D. L., Lee, K. J., Jagirdar, K., Pflugfelder, A., Stark, M. S., McMeniman, E. K., Soyer, H. P. and Sturm, R. A. (2019). Naevus count and MC1R R alleles contribute to melanoma risk. British Journal of Dermatology, 181 (5), e119-e119. doi: 10.1111/bjd.18487

Stark, Mitchell S. (2019). Large-giant congenital melanocytic nevi: moving beyond NRAS mutations. Journal of Investigative Dermatology, 139 (4), 756-759. doi: 10.1016/j.jid.2018.10.003

Duffy, D. L., Lee, K. J., Jagirdar, K., Pflugfelder, A., Stark, M. S., McMeniman, E. K., Soyer, H. P. and Sturm, R. A. (2019). High naevus count and MC1R red hair alleles contribute synergistically to increased melanoma risk. British Journal of Dermatology, 181 (5) bjd.17833, 1009-1016. doi: 10.1111/bjd.17833

Tan, Jean-Marie, Tom, Lisa N., Soyer, H. Peter and Stark, Mitchell S. (2018). Defining the molecular genetics of dermoscopic naevus patterns. Dermatology , 235 (1), 1-16. doi: 10.1159/000493892

Stark, Mitchell S., Tan, Jean-Marie, Tom, Lisa, Jagirdar, Kasturee, Lambie, Duncan, Schaider, Helmut, Soyer, H. Peter and Sturm, Richard A. (2018). Whole-exome sequencing of acquired nevi identifies mechanisms for development and maintenance of benign neoplasms (vol 138, pg 1636, 2018). Journal of Investigative Dermatology, 138 (9), 2085-2085. doi: 10.1016/j.jid.2018.06.174

Stark, Mitchell S., Tan, Jean-Marie, Tom, Lisa, Jagirdar, Kasturee, Lambie, Duncan, Schaider, Helmut, Soyer, H. Peter and Sturm, Richard A. (2018). Whole-exome sequencing of acquired nevi identifies mechanisms for development and maintenance of benign neoplasms. Journal of Investigative Dermatology, 138 (7), 1636-1644. doi: 10.1016/j.jid.2018.02.012

Tan, J. M., Tom, L. N., Jagirdar, K., Lambie, D., Schaider, H., Sturm, R. A., Soyer, H. P. and Stark, M. S. (2018). The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive MAPK pathway activation. British Journal of Dermatology, 178 (1), 191-197. doi: 10.1111/bjd.15809

Emran, Abdullah Al, Marzese, Diego M., Menon, Dinoop Ravindran, Stark, Mitchell S., Torrano, Joachim, Hammerlindl, Heinz, Zhang, Gao, Brafford, Patricia, Salomon, Matthew P., Nelson, Nellie, Hammerlindl, Sabrina, Gupta, Deepesh, Mills, Gordon B., Lu, Yiling, Sturm, Richard A., Flaherty, Keith, Hoon, Dave S. B., Gabrielli, Brian, Herlyn, Meenhard and Schaider, Helmut (2017). Distinct histone modifications denote early stress-induced drug tolerance in cancer. Oncotarget, 9 (9), 8206-8222. doi: 10.18632/oncotarget.23654

Stark, Mitchell S. (2017). Melanoma treatment guided by a panel of microRNA biomarkers. Melanoma Management, 4 (2), 71-74. doi: 10.2217/mmt-2017-0006

Stark, Mitchell S., Tom, Lisa N., Boyle, Glen M., Bonazzi, Vanessa F., Soyer, H. Peter, Herington, Adrian C., Pollock, Pamela M. and Hayward, Nicholas K. (2016). The 'Melanoma-enriched' microRNA miR-4731-5p acts as a tumour suppressor. Oncotarget, 7 (31), 49677-49687. doi: 10.18632/oncotarget.10109

Stark, Mitchell S., Bonazzi, Vanessa F., Boyle, Glen M., Palmer, Jane M., Symmons, Judith, Lanagan, Catherine M., Schmidt, Christopher W., Herington, Adrian C., Ballotti, Robert, Pollock, Pamela M. and Hayward, Nicholas K. (2015). miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma. Oncotarget, 6 (19), 17753-17763. doi: 10.18632/oncotarget.3924

Tembe, Varsha, Schramm, Sarah-Jane, Stark, Mitchell, Patrick, Ellis, Jayaswal, Vivek, Tang, Yue Hang, Barbour, Andrew, Hayward, Nicholas K., Thompson, John F., Scolyer, Richard A., Yang, Yee Hwa and Mann, Graham J. (2015). MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis. Pigment Cell and Melanoma Research, 28 (3), 254-266. doi: 10.1111/pcmr.12343

Stark, Mitchell S., Klein, Kerenaftali, Weide, Benjamin, Haydu, Lauren E., Pflugfelder, Annette, Tang, Yue Hang, Palmer, Jane M., Whiteman, David C., Scolyer, Richard A., Mann, Graham J., Thompson, John F., Long, Georgina V., Barbour, Andrew P., Soyer, H. Peter, Garbe, Claus, Herington, Adrian, Pollock, Pamela M. and Hayward, Nicholas K. (2015). The Prognostic and Predictive Value of Melanoma-related MicroRNAs Using Tissue and Serum: A MicroRNA Expression Analysis. EBioMedicine, 2 (7), 671-680. doi: 10.1016/j.ebiom.2015.05.011

Aoude, Lauren G., Pritchard, Antonia L., Robles-Espinoza, Carla Daniela, Wadt, Karin, Harland, Mark, Choi, Jiyeon, Gartside, Michael, Quesada, Victor, Johansson, Peter, Palmer, Jane M., Ramsay, Andrew J., Zhang, Xijun, Jones, Kristine, Symmons, Judith, Holland, Elizabeth A., Schmid, Helen, Bonazzi, Vanessa, Woods, Susan, Dutton-Regester, Ken, Stark, Mitchell S., Snowden, Helen, van Doom, Remco, Montgomery, Grant W., Martin, Nicholas G., Keane, Thomas M., Lopez-Otin, Carlos, Gerdes, Anne-Marie, Olsson, Hakan, Ingvar, Christian ... Hayward, Nicholas K. (2015). Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. Journal of the National Cancer Institute, 107 (2) dju408, 1-7. doi: 10.1093/jnci/dju408

Stark, Mitchell S. (2014). miRNAs: back seat drivers no more. Pigment Cell & Melanoma Research, 27 (4), 510-511. doi: 10.1111/pcmr.12247

Dutton-Regester, K., Kakavand, H., Aoude, L.G., Stark, M.S., Gartside, M.G., Johansson, P., O'Connor, L., Lanagan, C., Tembe, V., Pupo, G.M., Haydu, L.E., Schmidt, C.W., Mann, G.J., Thompson, J.F., Scolyer, R.A. and Hayward, N.K. (2013). Melanomas of unknown primary have a mutation profile consistent with cutaneous sun-exposed melanoma. Pigment Cell and Melanoma Research, 26 (6), 852-860. doi: 10.1111/pcmr.12153

Mould, Arne W., Pang, Zhenyi, Pakusch, Miha, Tonks, Ian D., Stark, Mitchell, Carrie, Dianne, Mukhopadhyay, Pamela, Seidel, Annica, Ellis, Jonathan J., Deakin, Janine, Wakefield, Matthew J., Krause, Lutz, Blewitt, Marnie E. and Kay, Graham F. (2013). Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation. Epigenetics and Chromatin, 6 (19) 19, 1-16. doi: 10.1186/1756-8935-6-19

Brooks, Kelly, Chia, Kee Ming, Spoerri, Loredana, Mukhopadhyay, Pamela, Wigan, Matthew, Stark, Mitchell, Pavey, Sandra and Gabrielli, Brian (2013). Defective decatenation checkpoint function is a common feature of melanoma. Journal of Investigative Dermatology, 134 (1), 150-158. doi: 10.1038/jid.2013.264

Dutton-Regester, Ken, Aoude, Lauren G., Nancarrow, Derek J., Stark, Mitchell S., O'Connor, Linda, Lanagan, Cathy, Pupo, Gulietta M., Tembe, Varsha, Carter, Candace D., O'Rourke, Michael, Scolyer, Richard A., Mann, Graham J., Schmidt, Christopher W., Herington, Adrian and Hayward, Nicholas K. (2012). Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene. Genes Chromosomes and Cancer, 51 (5), 452-461. doi: 10.1002/gcc.21932

Bonazzi, Vanessa F., Stark, Mitchell S. and Hayward, Nicholas K. (2012). MicroRNA regulation of melanoma progression. Melanoma Research, 22 (2), 101-113. doi: 10.1097/CMR.0b013e32834f6fbb

Bonazzi, Vanessa F., Nancarrow, Derek J., Stark, Mitchell S., Moser, Ralf J., Boyle, Glen M., Aoude, Lauren G., Schmidt, Christopher and Hayward, Nicholas K. (2011). Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma. PLoS One, 6 (10) e26121, 1-9. doi: 10.1371/journal.pone.0026121

Boyle, Glen M., Woods, Susan L., Bonazzi, Vanessa F., Stark, Mitchell S., Hacker, Elke, Aoude, Lauren G., Dutton-Regester, Ken, Cook, Anthony L., Sturm, Richard A. and Hayward, Nicholas K. (2011). Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor. Pigment Cell and Melanoma Research, 24 (3), 525-537. doi: 10.1111/j.1755-148X.2011.00849.x

Tyagi, Sonika, Stark, Mitchell S., Hayward, Nicholas K., Whiteman, David C. and Nancarrow, Derek J. (2010). WebFOG: A web tool to map genomic features onto genes. Biochemical and Biophysical Research Communications, 401 (3), 447-450. doi: 10.1016/j.bbrc.2010.09.077

Demenais, F., Mohamdi, H., Chaudru, V., Goldstein, A. M., Newton Bishop, J. A., Bishop, D. T., Kanetsky, P. A., Hayward, N. K., Gillanders, E., Elder, D. E., Avril, M. F., Azizi, E., van Belle, P., Bergman, W., Bianchi-Scarra, G., Brassac-de Paillerets, B., Calista, D., Carrera, C., Hansson, J., Harland, M., Hogg, D., Hoiom, V., Holland, E. A., Ingvar, C., Landi, M. T., Lang, J. M., Mackie, R. M., Mann, G. J., Ming, M. E. ... Melanoma Genetics Consortium (2010). Association of MC1R variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: A GenoMEL study. Journal of the National Cancer Institute, 102 (20), 1568-1583. doi: 10.1093/jnci/djq363

Whiteman, D.C., Parmar, P., Fahey, P., Moore, S.P., Stark, M., Zhao, Z.Z., Montgomery, G.W., Green, A.C., Hayward, N.K., Webb, P.M., Australian Cancer Study and Aoude, Lauren (2010). Association of Helicobacter pylori infection with reduced risk for esophageal cancer is independent of environmental and genetic modifiers. Gastroenterology, 139 (1), 73-83. doi: 10.1053/j.gastro.2010.04.009

Dry, Jonathan R., Pavey, Sandra, Pratilas, Christine A., Harbron, Chris, Runswick, Sarah, Hodgson, Darren, Chresta, Christine, McCormack, Rose, Byrne, Natalie, Cockerill, Mark, Graham, Alexander, Beran, Garry, Cassidy, Andrew, Haggerty, Carolyn, Brown, Helen, Ellison, Gillian, Dering, Judy, Taylor, Barry S., Stark, Mitchell, Bonazzi, Vanessa, Ravishankar, Sugandha, Packer, Leisl, Xing, Feng, Solit, David B., Finn, Richard S., Rosen, Neal, Hayward, Nicholas K., French, Tim and Smith, Paul D. (2010). Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244). Cancer Research, 70 (6), 2264-2273. doi: 10.1158/0008-5472.CAN-09-1577

Stark, Mitchell S., Tyagi, Sonika, Nancarrow, Derek J., Boyle, Glen M., Cook, Anthony L., Whiteman, David C., Parsons, Peter G., Schmidt, Christopher, Sturm, Richard A. and Hayward, Nicholas K. (2010). Characterization of the melanoma miRNAome by deep sequencing. PLoS One, 5 (3) e9685, e9685-1-e9685-9. doi: 10.1371/journal.pone.0009685

Bloethner, Sandra, Mould, Arne, Stark, Mitchell and Hayward, Nicholas K. (2008). Identification of ARHGEF17, DENND2D, FGFR3, and RBI mutations in melanoma by inhibition of nonsense-mediated mRNA decay. Genes, Chromosomes and Cancer, 47 (12), 1076-1085. doi: 10.1002/gcc.20598

Doecke, James, Zhao, Zhen Zhen, Pandeya, Nirmala, Sadeghi, Shahram, Stark, Mitchell, Green, Adele C., Hayward, Nicholas K., Webb, Penlope M. and Whiteman, David C. (2008). Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma. International Journal of Cancer, 123 (1), 174-180. doi: 10.1002/ijc.23410

Brown, K. M., MacGregor, S., Montgomery, G. W., Craig, D. W., Zhao, Z. Z., Iyadurai, K., Henders, A. K., Homer, N., Campbell, M. J., Stark, M., Thomas, S., Schmid, H., Maskiell, J. A., Jetann, J., Ferguson, M., Stephan, D. A., Cust, A. E., Whiteman, D. C., Green, A., Olsson, H., Puig, S., Ghiorzo, P., Hansson, J., Demenais, F., Goldstein, A. M., Gruis, N. A., Elder, D. E., Newton Bishop, J., Kefford, R. F. ... Hayward, N. (2008). Common sequence variants on 20q11.22 confer melanoma susceptibility. Nature Genetics, 40 (7), 838-840. doi: 10.1038/ng.163

Harland, Mark, Goldstein, Alisa M., Kukalizch, Kairen, Taylor, Claire, Hogg, David, Puig, Susana, Badenas, Celia, Gruis, Nelleke, ter Huurne, Jeanet, Bergman, Wilma, Hayward, Nicholas K., Stark, Mitchell, Tsao, Hensin, Tucker, Margret A., Landi, Maria Teresa, Scarra, Giovanna B., Ghiorzo, Paola, Kanetsky, Peter A., Elder, David, Mann, Graham J., Holland, Elizabeth A., Bishop, D. Timothy and Newton Bishop, Julia (2008). A comparison of CDKN2A mutation detection within the Melanoma Genetics Consortium (GenoMEL). European Journal of Cancer, 44 (9), 1269-1274. doi: 10.1016/j.ejca.2008.03.005

Sturm, Richard A., Duffy, David L., Zhao, Zhen Zhen, Leite, Fabio P.N., Stark, Mitchell S., Hayward, Nicholas K., Martin, Nicholas G. and Montgomery, Grant W. (2008). A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye colour. The American Journal of Human Genetics, 82 (2), 424-431. doi: 10.1016/j.ajhg.2007.11.005

Doecke, J D, Zhao, Z Z, Stark, M S, Green, A C, Hayward, N K, Montgomery, G W, Webb, P M and Whiteman, D C (2008). Single nucleotide polymorphisms in obesity-related genes and the risk of esophageal cancers. Cancer Epidemiology, Biomarkers & Prevention, 17 (4), 1007-1012. doi: 10.1158/1055-9965.EPI-08-0023

Nancarrow, Derek J., Handoko, Herlina Y., Stark, Mitchell S., Whiteman, David C. and Hayward, Nicholas K. (2007). SiDCoN: A tool to aide scoring of DNA copy number changes in SNP chip data. PLoS One, 2 (10) e1093, e1093. doi: 10.1371/journal.pone.0001093

Packer, Leisl M., Pavey, Sandra J., Boyle, Glen M., Stark, Mitchell S., Ayub, Ana L., Rizos, Helen and Hayward, Nicholas K. (2007). Gene expression profiling in melanoma identifies novel downstream effectors of p14ARF. International Journal of Cancer, 121 (4), 784-790. doi: 10.1002/ijc.22725

Pujana, M. A., Ruiz, A., Badenas, C., Puig-Butille, J-A., Nadal, M., Stark, M., Gomez, L., Valls, J., Sole, X., Hernandez, P., Cerrato, C., Madrigal, I., de Cid, R., Aguilar, H., Capella, G., Cal, S., James, M. R., Walker, G. J., Malvehy, J., Mila, M., Hayward, N. K., Estivill, X. and Puig, S. (2007). Molecular characterization of a t(9;12)(p21;q13) balanced chromosome translocation in combination with integrative genomics analysis identifies C9orf14 as a candidate tumor-suppressor. Genes, Chromosomes & Cancer, 46 (2), 155-162. doi: 10.1002/gcc.20396

Loffler, Kelly A., Biondi, Christine A., Gartside, Michael, Waring, Paul, Stark, Mitchell, Serewko-Auret, Magdalena M., Muller, H. Konrad, Hayward, Nicholas K. and Kay, Graham F. (2007). Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1. International Journal of Cancer, 120 (2), 259-267. doi: 10.1002/ijc.22288

Lang, J, Hayward, N, Goldgar, D, Tsao, H, Hogg, D, Palmer, J, Stark, M, Tobias, ES and MacKie, R (2007). The M531 mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry. Genes Chromosomes & Cancer, 46 (3), 277-287. doi: 10.1002/gcc.20410

Stark, M. and Hayward, N. (2007). Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-denisty single-nucleotide polymorphism arrays. Cancer Research, 67 (6), 2632-2642. doi: 10.1158/0008-5472.CAN-06-4152

Goldstein, Alisa M., Chan, May, Harland, Mark, Gillanders, Elizabeth M., Hayward, Nicholas K., Avril, Marie-Francoise, Azizi, Esther, Bianchi-Scarra, Giovanna, Bishop, D. Timothy, Bressac-de Paillerets, Brigitte, Bruno, William, Calista, Donato, Cannon Albright, Lisa A., Demenais, Florence, Elder, David E., Ghiorzo, Paola, Gruis, Nelleke A., Hansson, Johan, Hogg, David, Holland, Elizabeth A., Kanetsky, Peter A., Kefford, Richard F., Landi, Maria Teresa, Lang, Julie, Leachman, Sancy A., MacKie, Rona M., Magnusson, Veronica, Mann, Graham J., Niendorf, Kristin ... Melanoma Genetics Consortium (GenoMEL) (2006). High-risk Melanoma Susceptibility Genes and Pancreatic Cancer, Neural System Tumors, and Uveal Melanoma across GenoMEL. Cancer research, 66 (20), 9818-9828. doi: 10.1158/0008-5472.CAN-06-0494

Packer, Leisl, Pavey, Sandra, Parker, Andrew, Stark, Mitchell, Johansson, Peter, Clarke, Belinda, Pollock, Pamela, Ringner, Markus and Hayward, Nicholas (2006). Osteopontin is a Downstream Effector of the PI3-kinase Pathway in Melanomas that is Inversely Correlated with Functional PTEN. Carcinogenesis, 27 (9), 1778-1786. doi: 10.1093/carcin/bgl016

Curtin, John A., Stark, Mitchell S., Pinkel, Daniel, Hayward, Nicholas K. and Bastian, Boris C. (2006). PI3-Kinase Subunits Are Infrequent Somatic Targets in Melanoma. Journal of Investigative Dermatology, 126 (7), 1660-1663. doi: 10.1038/sj.jid.5700311

Stark, M., Puig-Butille, J. A., Walker, G., Badenas, C., Malvehy, J., Hayward , N. and Puig, S. (2006). Mutation of the tumour suppressor p33ING1b is rare in melanoma. British Journal of Dermatology, 155 (1), 94-99. doi: 10.1111/j.1365-2133.2006.07274.x

James, Michael R., Dumeni, Troy, Stark, Mitchell S., Duffy, David L., Montgomery, Grant W., Martin, Nicholas G. and Hayward, Nicholas K. (2006). Rapid screening of 4000 individuals for germ-line variations in the BRAF gene. Clinical Chemistry, 52 (9), 1675-1678. doi: 10.1373/clinchem.2006.070169

James, Michael R., Roth, Richard B., Shi, Michael M., Kammerer, Stefan, Nelson, Matthew R., Stark, Mitchell S., Dumenil, Troy, Montgomery, Grant W., Hayward, Nicholas K., Martin, Nicholas G., Braun, Andreas and Duffy, David L. (2005). BRAF Polymorphisms and Risk of Melanocytic Neoplasia. Journal of Investigative Dermatology, 125 (6), 1252-1258. doi: 10.1111/j.0022-202X.2005.23937.x

Zuidervaart, W., van Nieuwpoort, F., Stark, M., Dijkman, R., Packer, L., Borgstein, A. -M., Pavey, S., van der Velden, P., Out, C., Jager, M. J., Hayward, N. K. and Gruis, N. A. (2005). Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS. British Journal of Cancer, 92 (11), 2032-2038. doi: 10.1038/sj.bjc.6602598

Pavey, Sandra, Johansson, Peter, Packer, Leisl, Taylor, Jennifer, Stark, Mitchell, Pollock, Pamela M., Walker, Graeme J., Boyle, Glen M., Harper, Ursula, Cozzi, Sarah-Jane, Hansen, Katherine, Yudt, Laura, Schmidt, Chris, Hersey, Peter, Ellem, Kay A. O., O'Rourke, Michael G. E., Parsons, Peter G., Meltzer, Paul, Ringnér, Markus and Hayward, Nicholas K. (2004). Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene, 23 (23), 4060-4067. doi: 10.1038/sj.onc.1207563

Biondi, C. A., Gartside, M. G., Waring, P., Loffler, K. A., Stark, M. S., Magnuson, M. A., Kay, G. F. and Hayward, N. K. (2004). Conditional inactivation of the Men1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues. Molecular And Cellular Biology, 24 (8), 3125-3131. doi: 10.1128/MCB.24.8.3125-3131.2004

Vajdic, C, Kricker, A, Duffy, DL, Aitken, JF, Stark, M, ter Huurne, JAC, Martin, NG, Armstrong, BK and Hayward, NK (2003). Ocular melanoma is not associated with CDKN2A or MC1R variants - a population-based study. Melanoma Research, 13 (4), 409-413. doi: 10.1097/01.cmr.0000056244.56735.28

Gillanders, Elizabeth, Juo, Suh-Hang Hank, Holland, Elizabeth A., Jones, MaryPat, Nancarrow, Derek, Freas-Lutz, Diana, Sood, Raman, Park, Naeun, Faruque, Mezbah, Markey, Carol, Kefford, Richard F., Palmer, Jane, Bergman, Wilma, Bishop, D. Timothy, Tucker, Margaret A., Bressac-de Paillerets, Brigitte, Hansson, Johan, The Lund Melanoma Study Group, Stark, Mitchell, Gruis, Nelleke, Newton Bishop, Julia, Goldstein, Alisa M., Bailey-Wilson, Joan E., Mann, Graham J., Hayward, Nicholas, Trent, Jeffrey, Martin, Nicholas G. and The Melanoma Genetics Consortium (2003). Localization of a novel melanoma susceptibility locus to 1p22. American Journal of Human Genetics, 73 (2), 301-313. doi: 10.1086/377140

Pollock, Pamela M., Harper, Ursula L., Hansen, Katherine S., Yudt, Laura M., Stark, Mitchell, Robbins, Christiane M., Moses, Tracy Y., Hostetter, Galen, Wagner, Urs, Kakareka, John, Salem, Ghadi, Pohida, Tom, Heenan, Peter, Duray, Paul, Kallioniemi, Olli, Hayward, Nicholas K., Trent, Jeffrey M. and Meltzer, Paul S. (2003). High frequency of BRAF mutations in nevi. Nature Genetics, 33 (1), 19-20. doi: 10.1038/ng1054

Pollock, Pamela M., Stark, Mitchell S., Palmer, Jane M., Walters, Marilyn K., Aitken, Joanne F., Martin, Nicholas G. and Hayward, Nicholas K. (2001). Mutation analysis of the CDKN2A promoter in Australian melanoma families. Genes Chromosomes and Cancer, 32 (1), 89-94. doi: 10.1002/gcc.1170

Welch, John, Millar, Doug, Goldman, Alana, Heenan, Peter, Stark, Mitchell, Eldon, Michael, Clark, Susan, Martin, Nicholas G. and Hayward, Nicholas K. (2001). Lack of Genetic and Epigenetic Changes in CDKN2A in Melanocytic Nevi [Letter to the editor]. Journal of Investigative Dermatology, 117 (2), 383-384. doi: 10.1046/j.0022-202x.2001.01391.x

Box, N. F., Duffy, D. L., Chen, W., Stark, M., Martin, N. G., Sturm, R. A. and Hayward, N. K. (2001). MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations. American Journal of Human Genetics, 69 (4), 765-773. doi: 10.1086/323412

Harris, Teresa, Zaenker, Pauline, McEvoy, Ashleigh C., Soyer, H. Peter, Khattak, Muhammad A., Ziman, Melanie, Millward, Michael, Gray, Elin S. and Stark, Mitchell S. (2024). Assessment of precision melanoma diagnostics: Circulating microrna expression to monitor late-stage treatment. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-7626

Zhou, C., Tan, S. X., Kao, Y., Claeson, M., Brown, S., Lambie, D., Whiteman, D., Soyer, H., Stark, M., Nguyen, Q. and Khosrotehrani, K. (2023). 275 Spatial transcriptomics of early invasive melanomas reveals molecular determinants of patient survival. 1st International Societies for Investigative Dermatology Meeting (ISID 2023), Tokyo, Japan, 10 - 13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.279

Betz-Stablein, B. D., Rutjes, C., Kahler, S., Mothershaw, A., Jayasinghe, D., Stark, M., Janda, M. and Soyer, H. (2023). 203 Automated skin surface phenotype for melanoma risk assessment. 1st International Societies for Investigative Dermatology Meeting (ISID 2023), Tokyo, Japan, 10 - 13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.205

Kahler, Sam, Rutjes, Chantal, Yan, Siyuan, Mothershaw, Adam, Yu, Zhen, Jayasinghe, Dilki, Ge, Zongyuan, Stark, Mitchell, Janda, Monika, Soyer, Peter and Betz-Stablein, Brigid (2023). Automated photodamage assessment from 3D total body photography for an objective assessment of melanoma risk. Australasian College of Dermatologists 55th Annual Scientific Meeting, Engage, Enhance, Elevate, Virtual, 27-29 May 2023. Richmond, VIC Australia: John Wiley & Sons.

Muse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. 114th Annual Meeting of the American Association for Cancer Research (AACR), Orlando Fl, Apr 14-19, 2023. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2023-6000

Kan, C., Crovetto, N., Landreneau, R., Li, L., Soyer, H., Stark, M. S. and Gunn, S. (2020). Identification of a novel microrna panel: potential biomarkers for non-small cell lung cancer. Southern Regional Meeting of the American-Federation-for-Medical-Research (AFMR), New Orleans, LA, United States, 13-15 February 2020. London, United Kingdom: B M J Group. doi: 10.1136/jim-2020-SRM.565

Emran, A., Marzese, D. M., Menon, D. R., Stark, M., Torrano, J., Hammerlindl, H., Zhang, G., Brafford, P., Hammerlindl, S., Gupta, D., Mills, G. B., Lu, Y., Flaherty, K., Sturm, R., Hoon, D. S. B., Gabrielli, B., Herlyn, M. and Schaider, H. (2018). Distinct epigenetic remodelling defines early stress-induced drug tolerance in melanoma. Australasian College of Dermatologists, 51st Annual Scientific Meeting, Gold Coast, QLD, Australia , 19–22 May 2018. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/ajd.16_12815

Stark, Mitchell S., Tan, Jean-Marie, Tom, Lisa, Jagirdar, Kasturee, Lambie, Duncan, Schaider, Helmut, Soyer, H. Peter and Sturm, Richard A. (2018). Whole-exome sequencing of acquired nevi identifies novel mechanisms for development and maintenance of benign neoplasms. Annual Meeting of the American Association for Cancer Research (AACR), Chicago, Illinois, 14-18 April 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2018-5376

Tan, J-M., Tom, L., Jagirdar, K., Lambie, D., Sturm, R., Soyer, P. and Stark, M. (2017). The prevalence of BRAF and NRAS in dermoscopic subtypes of acquired naevi. Australasian College of Dermatologists 50th Annual Scientific Meeting, Darling Harbour, New South Wales, Australia, 6–9 May 2017. Richmond, VIC., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.21_12652

Stark, M., Gray, E., Ziman, M., Soyer, H. P. and Schaider, H. (2016). Can melanoma treatment be guided by a panel of predictive and prognostic microRNA biomarkers?. 16th World Congress on Cancers of the Skin , Vienna, Austria, 31 August - 3 September 2016. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Emran, A. A., Menon, D. R., Marzese, D., Hammerlindl, H., Brafford, P., Stark, M., Huang, S., Hammerlindl, S., Gupta, D., Soyer, P., Sturm, R., Hoon, D., Gabrielli, B., Herlyn, M. and Schaider, H. (2016). Epigenetic remodelling of H3K9Me3 leads to early stress induced drug tolerance in cancer. Asia‐Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell.

Ahmed, F., Tonnessen, C., Spoerri, L., Daignault, S., Stark, M., Schaider, H., Hill, M. and Haass, N. (2016). Identification of unique molecular signatures of differentially cycling tumour cell subpopulations in a 3D melanoma model. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584

Wright, C. M., Francis, S. M. Savarimuthu, Sriram, K. B., Stark, M. S., Hayward, N. K., Yang, I. A., Bowman, R. V. and Fong, K. M. (2013). Distinct profiles for lung cancer and its major subtypes. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12045

Wright, C. M., Francis, S. M. S., Sriram, K. B., Quinn, K. R., Stark, M. S., Hayward, N. K., Yang, I. A., Bowman, R. V. and Fong, K. M. (2011). Mapping the lung cancer methylome. 3rd Australian Lung Cancer Conference (ALCC), Melbourne VIC, Australia, 6-9 October 2010. Philadelphia PA, United States: Lippincott Williams & Wilkins.

Pollock, Pamela. M., Stark, Mitchell, Palmer, Jane M., Walters, Marilyn K., Martin, Nick G., Green, Adele C. and Hayward, Nicholas K. (2001). Mutation analysis of the CDKN2A promoter in Australian melanoma families. Unknown, Unknown, Unknown. New York, NY, United States: Springer Nature. doi: 10.1038/87254

Dr Mitchell Stark

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