Professor Trent Munro
Professor
Australian Institute for Bioengineering and Nanotechnology/BASE facility
| Featured projects | Duration |
|---|---|
|
Using nanopore sequencing to test mRNA vaccine quality. Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2022 |
Book Chapters
Munro, Trent P., Pilbrough, Warren, Hughes, Benjamin S. and Gray, Peter P. (2019). Cell line isolation and design. Comprehensive biotechnology. (pp. 144-153) edited by Murray Moo-Young. Oxford, United Kingdom: Pergamon. doi: 10.1016/B978-0-444-64046-8.00013-6
Codamo, Joe, Munro, Trent P., Hughes, Benjamin S., Song, Michael and Gray, Peter P. (2012). An optimised transfection platform for the Epi-CHO transient expression system in serum-free media. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 19-23) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-0884-6_3
Hou, Jeff Jia Cheng, Song, Michael, Munro, Trent P. and Gray, Peter P. (2012). Analysis of protein expression via alternate 3’ Untranslated Region (UTR) signals through the use of site specific recombination. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 47-51) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-0884-6_8
Munro, Trent P., Pilbrough, Warren, Hughes, Benjamin S. and Gray, Peter P. (2011). Cell line isolation and design. Scientific Fundamentals of Biotechnology. (pp. 169-178) edited by Murray Moo-Young, Michael Butler, Colin Webb, Antonio Moreira,, Bernard Grodzinski, Z. F. Cui and Spiros Agathos. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-08-088504-9.00024-6
Journal Articles
Nöbel, Matthias, Barry, Craig, MacDonald, Michael A., Baker, Kym, Shave, Evan, Mahler, Stephen, Munro, Trent, Martínez, Verónica S., Nielsen, Lars K. and Marcellin, Esteban (2024). Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation. Biotechnology and Bioengineering, 121 (4), 1371-1383. doi: 10.1002/bit.28613
Oyola-Lozada, Maria Giuliana, Pregelj, Lisette, Jenkins, Anna, Siegel, Evan, Munro, Trent and Hine, Damian (2024). Anticipatory regulation for pandemic responses: are we there yet?. Trends in Biotechnology, 42 (9), 1067-1071. doi: 10.1016/j.tibtech.2024.02.016
Williamson, Rhys, Munro, Trent, Ascher, David, Robertson, Avril and Pregelj, Lisette (2024). Are manufacturing patents to blame for biosimilar market launch delays?. Value in Health, 27 (3), 287-293. doi: 10.1016/j.jval.2023.12.005
Martínez, Verónica S., Rodriguez, Karen, McCubbin, Timothy, Tong, Junjie, Mahler, Stephen, Shave, Evan, Baker, Kym, Munro, Trent P. and Marcellin, Esteban (2024). Amino acid degradation pathway inhibitory by‐products trigger apoptosis in CHO cells. Biotechnology Journal, 19 (2) ARTN e2300338, e2300338. doi: 10.1002/biot.202300338
Chappell, Keith J., Mordant, Francesca L., Amarilla, Alberto A., Modhiran, Naphak, Liang, Benjamin, Li, Zheyi, Wijesundara, Danushka K., Lackenby, Julia A., Griffin, Paul, Bennet, Jillian K., Hensen, Luca, Zhang, Wuji, Nguyen, Thi H.O., Tran, Mai H., Tapley, Peter, Barnes, James, Reading, Patrick C., Kedzierska, Katherine, Ranasinghe, Charani, Subbarao, Kanta, Watterson, Daniel, Young, Paul R. and Munro, Trent P. (2023). Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial. eBioMedicine, 97 104842. doi: 10.1016/j.ebiom.2023.104842
Gunter, Helen M., Idrisoglu, Senel, Singh, Swati, Han, Dae Jong, Ariens, Emily, Peters, Jonathan R., Wong, Ted, Cheetham, Seth W., Xu, Jun, Rai, Subash Kumar, Feldman, Robert, Herbert, Andy, Marcellin, Esteban, Tropee, Romain, Munro, Trent and Mercer, Tim R. (2023). mRNA vaccine quality analysis using RNA sequencing. Nature Communications, 14 (1) 5663, 1-12. doi: 10.1038/s41467-023-41354-y
Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D. J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian M. T., Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L. ... Watterson, Daniel (2023). A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants. iScience, 26 (7) 107085, 107085. doi: 10.1016/j.isci.2023.107085
Deliyannis, Georgia, Gherardin, Nicholas A., Wong, Chinn Yi, Grimley, Samantha L., Cooney, James P., Redmond, Samuel J., Ellenberg, Paula, Davidson, Kathryn C., Mordant, Francesca L., Smith, Tim, Gillard, Marianne, Lopez, Ester, McAuley, Julie, Tan, Chee Wah, Wang, Jing J., Zeng, Weiguang, Littlejohn, Mason, Zhou, Runhong, Fuk-Woo Chan, Jasper, Chen, Zhi-wei, Hartwig, Airn E., Bowen, Richard, Mackenzie, Jason M., Vincan, Elizabeth, Torresi, Joseph, Kedzierska, Katherine, Pouton, Colin W., Gordon, Tom P., Wang, Lin-fa ... Godfrey, Dale I. (2023). Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine. eBioMedicine, 92 104574, 104574. doi: 10.1016/j.ebiom.2023.104574
Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0
Kouli, O., Murray, V., Bhatia, S., Cambridge, W. A., Kawka, M., Shafi, S., Knight, S. R., Kamarajah, S. K., McLean, K. A., Glasbey, J. C., Khaw, R. A., Ahmed, W., Akhbari, M., Baker, D., Borakati, A., Mills, E., Thavayogan, R., Yasin, I., Raubenheimer, K., Ridley, W., Sarrami, M., Zhang, G., Egoroff, N., Pockney, P., Richards, T., Bhangu, A., Creagh-Brown, B., Edwards, M., Harrison, E. M. ... Wischhusen, S. (2022). Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study. The Lancet Digital Health, 4 (7), e520-e531. doi: 10.1016/S2589-7500(22)00069-3
MacDonald, Michael A., Nöbel, Matthias, Martínez, Verónica S., Baker, Kym, Shave, Evan, Gray, Peter P., Mahler, Stephen, Munro, Trent, Nielsen, Lars K. and Marcellin, Esteban (2022). Engineering death resistance in CHO cells for improved perfusion culture. mAbs, 14 (1) e2083465, 1-13. doi: 10.1080/19420862.2022.2083465
Allard, Joanne L., Shields, Katherine A., Munro, Trent P. and Lua, Linda H.L. (2022). Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning. Chemico-Biological Interactions, 363 109996, 109996. doi: 10.1016/j.cbi.2022.109996
Mercer, Tim R., Munro, Trent and Mattick, John S. (2022). The potential of long noncoding RNA therapies. Trends in Pharmacological Sciences, 43 (4), 269-280. doi: 10.1016/j.tips.2022.01.008
Wan, Kanny K., Davis, Danielle, Lee, Taylor N., Ford-Scheimer, Stephanie L., Andreu, Antonio L., Bietrix, Florence, Bryans, Justin, Castro, Marco T., Chiba, Nobuyoshi, Faupel-Badger, Jessica M., Haynes, Brittany, Hirasawa, Ryutaro, Morel, Carlos M., Souza, Thiago Moreno L., Morrow, David, Munro, Trent, Newman, Stuart, Ussi, Anton E., Zorzal, Poliana B., Hall, Matthew D., Lo, Donald C. and Cutillo, Christine M. (2022). A call to action for translational sciences in COVID-19 and future pandemics. Nature Reviews Drug Discovery, 21 (3), 165-166. doi: 10.1038/d41573-022-00020-6
MacDonald, Michael A., Barry, Craig, Groves, Teddy, Martínez, Verónica S., Gray, Peter P., Baker, Kym, Shave, Evan, Mahler, Stephen, Munro, Trent, Marcellin, Esteban and Nielsen, Lars K. (2022). Modelling apoptosis resistance in CHO cells with CRISPR‐mediated knock‐outs of Bak1, Bax, and Bok. Biotechnology and Bioengineering, 119 (6), 1380-1391. doi: 10.1002/bit.28062
Chappell, Keith J., Mordant, Francesca L., Li, Zheyi, Wijesundara, Danushka K., Ellenberg, Paula, Lackenby, Julia A., Cheung, Stacey T. M., Modhiran, Naphak, Avumegah, Michael S., Henderson, Christina L., Hoger, Kym, Griffin, Paul, Bennet, Jillian, Hensen, Luca, Zhang, Wuji, Nguyen, Thi H. O., Marrero-Hernandez, Sara, Selva, Kevin J., Chung, Amy W., Tran, Mai H., Tapley, Peter, Barnes, James, Reading, Patrick C., Nicholson, Suellen, Corby, Stavroula, Holgate, Thomas, Wines, Bruce D., Hogarth, P Mark, Kedzierska, Katherine ... Munro, Trent P. (2021). Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial. The Lancet Infectious Diseases, 21 (10), 1383-1394. doi: 10.1016/S1473-3099(21)00200-0
He, Yaowu, Khan, Tashbib, Kryza, Thomas, Jones, Martina L., Goh, Justin B., Lyons, Nicholas J., Pearce, Lesley A., Lee, Michael D, Gough, Madeline, Rogers, Rebecca, Davies, Claire M,, Gilks, C. Blake, Hodgkinson, Thomas, Lourie, Rohan, Barry, Sinead C., Perrin, Lewis C., Williams, Charlotte C., Puttick, Simon, Adams, Timothy E., Munro, Trent P., Hooper, John D. and Chetty, Naven (2021). Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer. Molecular Pharmaceutics, 18 (9) acs.molpharmaceut.1c00401, 3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401
Watterson, Daniel, Wijesundara, Danushka K., Modhiran, Naphak, Mordant, Francesca L., Li, Zheyi, Avumegah, Michael S., McMillan, Christopher L. D., Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey T. M., Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L., Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam ... Chappell, Keith J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & Translational Immunology, 10 (4) e1269, e1269. doi: 10.1002/cti2.1269
MacDonald, Michael A., Nöbel, Matthias, Roche Recinos, Dinora, Martínez, Verónica S., Schulz, Benjamin L., Howard, Christopher B., Baker, Kym, Shave, Evan, Lee, Yih Yean, Marcellin, Esteban, Mahler, Stephen, Nielsen, Lars Keld and Munro, Trent (2021). Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications. Critical Reviews in Biotechnology, 42 (7), 1-17. doi: 10.1080/07388551.2021.1998821
Chandler, Peter G., Tan, Li Lynn, Porebski, Benjamin T., Green, James S., Riley, Blake T., Broendum, Sebastian S., Hoke, David E., Falconer, Robert J., Munro, Trent P., Buckle, Malcolm, Jackson, Colin J. and Buckle, Ashley M. (2021). Mutational and biophysical robustness in a prestabilized monobody. Journal of Biological Chemistry, 296 100447, 100447. doi: 10.1016/j.jbc.2021.100447
Chappell, Keith Joseph, Mordant, Francesca L., Li, Zheyi, Wijesundara, Danushka K., Ellenberg, Paula, Lackenby, Julia, Cheung, Stacey, Modhiran, Naphak, Avumegah, Michael S., Henderson, Christina L., Hoger, Kym, Bennet, Jillian, Hensen, Luca, Nguyen, Thi H. O., Marrero-Hernandez, Sara, Selva, Kevin J., AW, Chung, Tran, Mai H., Tapley, Peter, Reading, Patrick, Nicholson, Suellen, Corby, Stavroula, Holgate, Thomas, Wines, Bruce D., Hogarth, P. Mark, Kedzierska, Katherine, Purcell, Damian, Ranasinghe, Charani, Subbarao, Kanta ... Munro, Trent P. (2021). First report of a phase 1 randomised trial of molecular clamp-stabilised spike protein-based and MF59-adjuvanted vaccine for SARS-CoV-2. SSRN Electronic Journal. doi: 10.2139/ssrn.3769210
Playford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6
Pregelj, Lisette, Hine, Damian C., Oyola-Lozada, Maria G. and Munro, Trent P. (2020). Working hard or hardly working? Regulatory bottlenecks in developing a COVID-19 vaccine. Trends in Biotechnology, 38 (9), 943-947. doi: 10.1016/j.tibtech.2020.06.004
Jorgolli, Marsela, Nevill, Tanner, Winters, Aaron, Chen, Irwin, Chong, Su, Lin, Fen-Fen, Mock, Marissa, Chen, Ching, Le, Kim, Tan, Christopher, Jess, Philip, Xu, Han, Hamburger, Agi, Stevens, Jennitte, Munro, Trent, Wu, Ming, Tagari, Philip and Miranda, Les P. (2019). Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. Biotechnology and Bioengineering, 116 (9), 2393-2411. doi: 10.1002/bit.27024
Le, Kim, Tan, Christopher, Gupta, Shivani, Guhan, Trupti, Barkhordarian, Hedieh, Lull, Jonathan, Stevens, Jennitte and Munro, Trent (2018). A novel mammalian cell line development platform utilizing nanofluidics and optoelectro positioning technology. Biotechnology Progress, 34 (6), 1438-1446. doi: 10.1002/btpr.2690
Tharmalingam, Tharmala, Barkhordarian, Hedieh, Tejeda, Nicole, Daris, Kristi, Yaghmour, Sam, Yam, Pheng, Lu, Fang, Goudar, Chetan, Munro, Trent and Stevens, Jennitte (2018). Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line. Biotechnology Progress, 34 (3), 613-623. doi: 10.1002/btpr.2666
Orellana, Camila A., Marcellin, Esteban, Palfreyman, Robin W., Munro, Trent P., Gray, Peter P. and Nielsen, Lars K. (2018). RNA-seq highlights high clonal variation in monoclonal antibody producing CHO cells. Biotechnology Journal, 13 (3) 1700231, e1700231. doi: 10.1002/biot.201700231
DeMaria, Christine and Munro, Trent (2017). Introduction to special section on using pools to generate Good Laboratory Practice tox or other non-clinical material to accelerate development timelines. Biotechnology Progress, 33 (6), 1435-1435. doi: 10.1002/btpr.2583
Munro, Trent P., Le, Kim, Le, Huong, Zhang, Li, Stevens, Jennitte, Soice, Neil, Benchaar, Sabrina A., Hong, Robert W. and Goudar, Chetan T. (2017). Accelerating patient access to novel biologics using stable pool-derived product for non-clinical studies and single clone-derived product for clinical studies. Biotechnology Progress, 33 (6), 1476-1482. doi: 10.1002/btpr.2572
Frye, Christopher, Deshpande, Rohini, Estes, Scott, Francissen, Kathy, Joly, John, Lubiniecki, Anthony, Munro, Trent, Russell, Reb, Wang, Tongtong and Anderson, Karin (2016). Industry view on the relative importance of "clonality" of biopharmaceutical-producing cell lines. Biologicals, 44 (2), 117-122. doi: 10.1016/j.biologicals.2016.01.001
Seldon, T. A., Pryor, R., Palkova, A., Jones, M. L., Verma, N. D., Findova, M., Braet, K., Sheng, Y., Fan, Y., Zhou, Y. Y., Marks, J. D., Munro, T., Mahler, S. M., Barnard, R. T., Fromm, P. D., Silveira, P. A., Elgundi, Z., Ju, X., Clark, G. J., Bradstock, K. F., Munster, D. J. and Hart, D. N. J. (2015). Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation.. Leukemia, 30 (3), 692-700. doi: 10.1038/leu.2015.231
Taylor, Karin, Howard, Christopher B., Jones, Martina L., Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P. and Mahler, Stephen M. (2014). Nanocell targeting using engineered bispecific antibodies.. mAbs, 7 (1), 53-65. doi: 10.4161/19420862.2014.985952
Gillard, Marianne, Jia, Zhongfan, Hou, Jeff Jia Cheng, Song, Michael, Gray, Peter P., Munro, Trent P. and Monteiro, Michael J. (2014). Intracellular trafficking pathways for nuclear delivery of plasmid DNA complexed with highly efficient endosome escape polymers. Biomacromolecules, 15 (10), 3569-3576. doi: 10.1021/bm5008376
Goodall, Stephen, Howard, Christopher B., Jones, Martina L., Munro,Trent, Jia, Zhongfan, Monteiro, Michael J and Mahler, Stephen (2014). An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer. Journal of Chemical Technology and Biotechnology, 90 (7), 1222-1229. doi: 10.1002/jctb.4509
Gillard, Marianne, Jia, Zhongfan, Gray, Peter P., Munro, Trent P. and Monteiro, Michael J. (2014). Timed-release polymers as novel transfection reagents. Polymer Chemistry, 5 (10), 3372-3378. doi: 10.1039/c4py00176a
Hou, Jeff Jia Cheng, Hughes, Ben S., Smede, Matthew, Leung, Kar Man, Levine, Kara, Rigby, Susan, Gray, Peter P. and Munro, Trent P. (2014). High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system. New Biotechnology, 31 (3), 214-220. doi: 10.1016/j.nbt.2014.02.002
Chen, Xiaoli, Prowse, Andrew B. J., Jia, Zhongfan, Tellier, Helena, Munro,Trent P., Gray, Peter P. and Monteiro, Michael J. (2014). Thermoresponsive worms for expansion and release of human embryonic stem cells. Biomacromolecules, 15 (3), 844-855. doi: 10.1021/bm401702h
Menzies, Donna J., Cameron, Andrew, Munro, Trent, Wolvetang, Ernst, Grondahl, Lisbeth and Cooper-White, Justin J. (2013). Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly(ethylene glycol)-based hydrogels. Biomacromolecules, 14 (2), 413-423. doi: 10.1021/bm301652q
Prowse, Andrew B. J., Chong, Fenny, Elliott, David A., Elefanty, Andrew G., Stanley, Edouard G., Gray, Peter P., Munro, Trent P. and Osborne, Geoffrey W. (2012). Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro. PLoS One, 7 (12) e52214, e52214-1-e52214-10. doi: 10.1371/journal.pone.0052214
Zhu, Jiang, Wooh, Jong Wei, Hou, Jeff Jia Cheng, Hughes, Benjamin S., Gray, Peter P. and Munro, Trent P. (2012). Recombinant human albumin supports single cell cloning of CHO cells in chemically defined media. Biotechnology Progress, 28 (3), 887-891. doi: 10.1002/btpr.1549
Munro, Trent P., Mahler, Stephen M., Huang, Edwin P., Chin, David Y. and Gray, Peter P. (2011). Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates. mAbs, 3 (5), 440-452. doi: 10.4161/mabs.3.5.16968
Hou, Jeff Jia Cheng, Codamo, Joe, Pilbrough, Warren, Hughes, Benjamin, Gray, Peter P. and Munro, Trent P. (2011). New frontiers in cell line development: Challenges for biosimilars. Journal of Chemical Technology and Biotechnology, 86 (7), 895-904. doi: 10.1002/jctb.2574
Codamo, Joe, Hou, Jeff Jia Cheng, Hughes, Benjamin S., Gray, Peter P. and Munro, Trent P. (2011). Efficient mAb production in CHO cells incorporating PEI-mediated transfection, mild hypothermia and the co-expression of XBP-1. Journal of Chemical Technology and Biotechnology, 86 (7), 923-934. doi: 10.1002/jctb.2572
Falconer, Robert J., Chan, Cherrine, Hughes, Karen and Munro, Trent P. (2011). Stabilization of a monoclonal antibody during purification and formulation by addition of basic amino acid excipients. Journal of Chemical Technology and Biotechnology, 86 (7), 942-948. doi: 10.1002/jctb.2657
Codamo, Joe, Munro, Trent P., Hughes, Benjamin S., Song, Michael and Gray, Peter P. (2011). Enhanced CHO cell-based transient gene expression with the Epi-CHO expression system. Molecular Biotechnology, 48 (2), 109-115. doi: 10.1007/s12033-010-9351-9
Prowse, Andrew B. J., Chong, Fenny, Gray, Peter P. and Munro, Trent P. (2011). Stem cell integrins: Implications for ex-vivo culture and cellular therapies. Stem Cell Research, 6 (1), 1-12. doi: 10.1016/j.scr.2010.09.005
Prowse, Andrew B. J., Doran, Michael R., Cooper-White, Justin J., Chong, Fenny, Munro, Trent P., Fitzpatrick, Jane, Chung, Tung-Liang, Haylock, David N., Gray, Peter P. and Wolvetang, Ernst J. (2010). Long term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media. Biomaterials, 31 (32), 8281-8288. doi: 10.1016/j.biomaterials.2010.07.037
Doran, Michael R., Frith, Jessica E., Prowse, Andrew B. J., Fitzpatrick, Jane, Wolvetang, Ernst J., Munro, Trent P., Gray, Peter P. and Cooper-White, Justin J. (2010). Defined high protein content surfaces for stem cell culture. Biomaterials, 31 (19), 5137-5142. doi: 10.1016/j.biomaterials.2010.03.015
Jones, Martina L., Seldon, Therese, Smede, Matthew, Linville, Ashleigh, Chin, David Y., Barnard, Ross, Mahler, Stephen M., Munster, David, Hart, Derek, Gray, Peter P. and Munro, Trent P. (2010). A method for rapid, ligation-independent reformatting of recombinant monoclonal antibodies. Journal of Immunological Methods, 354 (1-2), 85-90. doi: 10.1016/j.jim.2010.02.001
Doran, M.R., Markway, B.D., Croll, T.I., Sara, S., Munro, T.P. and Cooper-White, J.J. (2009). Controlled presentation of recombinant proteins via a zinc-binding peptide-linker in two and three dimensional formats. BIOMATERIALS, 30 (34), 6614-6620. doi: 10.1016/j.biomaterials.2009.08.033
Pilbrough, Warren, Munro, Trent P. and Gray, Peter (2009). Intraclonal protein expression heterogeneity in recombinant CHO cells. PLoS One, 4 (12) e8432, e8432.1-e8432.11. doi: 10.1371/journal.pone.0008432
George, P.A., Doran, M.R., Croll, T.I., Munro, T.P. and Cooper-White, J.J. (2009). Nanoscale presentation of cell adhesive molecules via block copolymer self-assembly. BIOMATERIALS, 30 (27), 4732-4737. doi: 10.1016/j.biomaterials.2009.05.039
Munro, Trent (2009). To go boldly. Australian Life Scientist, 6 (5)
Munro, T. P., Kwon, S., Schnapp, B. J. and St Johnston, D. (2006). A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP. Journal of Cell Biology, 172 (4), 577-588. doi: 10.1083/jcb.200510044
Huynh, J. R., Munro, T. P., Smith-Litiere, K., Lepesant, J. A. and Johnston, D. S. (2004). The Drosophila hnRNPA/B homolog, Hrp48, is specifically required for a distinct step in osk mRNA localization. Developmental Cell, 6 (5), 625-635. doi: 10.1016/S1534-5807(04)00130-3
Shan, Jianguo, Munro, Trent P., Barbarese, Elisa, Carson, John H. and Smith, Ross (2003). A molecular mechanism for mRNA trafficking in neuronal dendrites. Journal of Neuroscience, 23 (26), 8859-8866. doi: 10.1523/jneurosci.23-26-08859.2003
Kwon, S., Abramson, T., Munro, T. P., John, C. M., Kohrmann, M. and Schnapp, B. J. (2002). UUCAC- and Vera-dependent localization of VegT RNA in Xenopus oocytes. Current Biology, 12 (7), 558-564. doi: 10.1016/S0960-9822(02)00740-6
Ma, Alice S. W., Moran-Jones, Kim, Shan, Jianguo, Munro, Trent P., Snee, Mark J., Hoek, Keith S. and Smith, Ross (2002). Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein. Journal of Biological Chemistry, 277 (20), 18010-18020. doi: 10.1074/jbc.M200050200
Snee, M., Kidd, G. J., Munro, T. P. and Smith, R. (2002). RNA trafficking and stabilization elements associate with multiple brain proteins. Journal of Cell Science, 115 (23), 4661-4669. doi: 10.1242/jcs.00137
Kwon, S., Abramson, T., Munro, T. P., John, C. M., Koehrmann, M. and Schnapp, B. J. (2001). Repeated UUCACs are general cis-acting localization motifs in maternal RNAs that establish the germ layers in Xenopus. Molecular Biology of The Cell, 12, 362A-362A.
Mouland, A. J., Xu, H. B., Cui, H. Y., Krueger, W., Munro, T. P., Prasol, M., Mercier, J., Rekosh, D., Smith, R., Barbarese, E., Cohen, E. A. and Carson, J. H. (2001). RNA trafficking signals in human immunodeficiency virus type 1. Molecular And Cellular Biology, 21 (6), 2133-2143. doi: 10.1128/MCB.21.6.2133-2143.2001
Shan, Jianguo, Moran-Jones, Kim, Munro, Trent P., Kidd, Grahame J., Winzor, Donald J., Hoek, Keith S. and Smith, Ross (2000). Binding of an RNA trafficking response element to heterogeneous nuclear ribonucleoproteins A1 and A2. Journal of Biological Chemistry, 275 (49), 38286-38295. doi: 10.1074/jbc.M007642200
Munro, Trent P., Magee, Rebecca J., Kidd, Grahame J., Carson, John H., Barbarese, Elisa, Smith, Lisa M. and Smith, Ross (1999). Mutational analysis of a heterogeneous nuclear ribonucleoprotein A2 response element for RNA trafficking. Journal of Biological Chemistry, 274 (48), 34389-34395. doi: 10.1074/jbc.274.48.34389
Conference Papers
Gillard, M., Jia, Z., Jia, J., Song, M., Gray, P. P., Munro, T. P. and Monteriro, M. J. (2015). Intracellular trafficking pathways for plasmid DNA complexed with highly efficient endosome escape polymers. European Society for Animal Cell Technology (ESACT), Barcelona, Spain, 31 May- 3 June 2015.
Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Munster, David, Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Ai, Lo, Tsun Ho, Shahin, Kifah, Clark, Georgina, Larsen, Stephen, Bradstock, Kenneth and Hart, Derek (2015). Human Cd83 Expression On Immune Cells Validates Anti-Cd83 Prophylaxis to Prevent Graft Versus Host Disease in Allogeneic Haematopoietic Cell Transplantation.. 14th Transplantation Science Symposium of the Transplantation-Society (TSS), Lorne, Australia, 11-13 November 2015. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Orellana, Camila A., Marcellin, Esteban, Munro, Trent, Gary, Peter P. and Nielsen, Lars K. (2015). Multi-omics approach for comparative studies of monoclonal antibody producing CHO cells. European Society for Animal Cell Technology (ESACT) Meeting, Barcelona, Spain, 31 May - 3 June 2015. London, United Kingdom: BioMed Central. doi: 10.1186/1753-6561-9-S9-O8
Hart, Derek N. J., Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Hsu, Blake, Munster, David J., Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Al, Lo, Tsun Ho, Shahin, Kifah, Larsen, Stephen Robert, Bradstock, Kenneth and Clark, Georgina (2015). Characterisation of human CD83 expression on immune cells and their targeting with CD83 antibodies to prevent graft versus host disease in allogeneic haematopoietic cell transplantation. 57th Annual Meeting of the American Society of Hematology, Orlando, FL, United States, 5-8 Dec 2015. WASHINGTON: AMER SOC HEMATOLOGY.
Verma, Nirupama D., Munster, David, Seldon, Therese, Sheng, Yong Hua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Phi Ai, Lo, Kevin, Shahin, Kifah, Elgundi, Zehra, Silveira, Pablo, Fromm, Phillip D., Clark, Georgina J., Larsen, Stephen, Bradstock, Kenneth and Hart, Derek N. J. (2015). The Human Monoclonal Antibody 3C12C, Targeting Activated Dendritic Cells Is a Potential New Immunosuppressive Agent. BMT Tandem Meetings, San Diego, CA United States, 11-15 February 2015. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.bbmt.2014.11.527
Hart, D. N. J., Elgundi, Z., Ju Xinsheng, Verma, N. D., Silveira, P. A., Fromm, P. D., Alingcastre, R., Munster, D. J., Seldon, T. A., Sheng, Y., Jones, M. L., Munro, T. P., Mahler, S., Barnard, R. T., Vu, P. A., Lo, K., Shahin, K., Larsen, S., Bradstock, K. and Clark, G. J. (2015). CD83 Expression On Human Immune Cells as a Target for Immunosuppression. 33rd Annual Scientific Meeting of the Transplantation Society of Australia and new Zealand, Canberra, ACT Australia, 21-23 June 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/icb.2015.75
Hart, D, Verma, N., Seldon, T, Sheng, Y., Pryor, R., Palkova, A., Findova, M., Jones, M., Munro, T., Mahler, S., Braet, K., Barnard, R., Marks, J., Coley, A., Fan, F., Zhou, Y., Vu, P, Lo, K., Shahin, K., Elgundi, Z., Silveira, P., Fromm, P., Clark, G., Larsen, S., Bradstock, K. and Munster, D. (2014). The Monoclonal Antibody 3C12C, Targeting CD83 Is a T Cell Sparing, Potential New Immunosuppressive Agent. 2014 World Transplant Congress, San Francicso Ca, 26 - 31 July 2014. Malden, MA United States: Wiley-Blackwell Publishing, Inc.. doi: 10.1111/ajt.12888
Gillard, M., Truong N. P., Jia, Z., Monteiro M. J. and Munro, T. P. (2013). Exploring endosomal pathways using novel nanoparticle polymers as transfection reagents. 11th Protein Expression in Animal Cells Conference, Kananaskis, AB, Canada, 22-25 September 2013.
Hart, D, Seldon, T, Jones, M, Sheng, Y, Palkova, A, Cullup, H, Munro, T, Sinfield, L, Rice, AM, Wilson, J, Gray, P, Barnard, R, Mahler, S and Munster, D (2009). Developing a Therapeutic Anti - Dendritic Cell Antibody to Prevent Graft Versus Host Disease. 51st Annual Meeting of the American Society of Hematology, New Orleans LA, 5-8 December 2009. Washington, D.C.: American Society of Hematology.
Smith, R. W., Shan, J., Munro, T., Barbarese, E. and Carson, J. H. (2002). A molecular mechanism for messenger RNA trafficking in neuronal dendrites. ComBio 2002, Sydney, 29 September - 3 October, 2002.
Ma, A. S. W., Snee, M. J., Moran-Jones, K., Munro, T., Kidd, G. J. and Smith, R. W. (2001). hnRNP A3, A novel RNA cytoplasmic trafficking response element binding protein. ASBMB, Canberra, ACT, Australia, 31 September - 4 October, 2001.
Munro, T. P., Ma, A. S. W., Snee, M., Carson, J. H. and Smith, R. W. (2000). Identification and subcellular localization of hnRNP A3: A protein that binds to the A2RE RNA trafficking sequence. 2000 FASEB Summer Research Conference, Snowmass, Colorado, 2-11 June, 2000.
Shan, J., Moran, K., Munro, T. P., Kidd, G., Winzor, D. J., Hoek, K. S. and Smith, R. W. (2000). Trafficking of myelin basic protein RNA: Assciation of hnRNPs A1, A2 and A3 with the hnRNP A2 response element. 2000 FASEB Summer Research Conf, Snowmass, Colorado, 2-11 June, 2000.
Munro, T., Magee, R. J., Kidd, G. J., Carson, J. H., Barbarese, E., Smith, L. M. and Smith, R. W. (1999). Mutational analysis of an hnRNP A2 response element for RNA trafficking. ComBio 99, Conrad Jupiters, Gold Coast, 27-30 September, 1999. Kent Town, SA: Aust. Society for Biochemistry & Molecular Biology.
Shan, J., Hoek, K. S., Kidd, G. J., Munro, T. P., Hall, D., Schindeler, A. J., Winzor, D. J. and Smith, R. W. (1999). Biosensor evidence for the existence of sequence-specific and nonspecific RNA binding sites on HNRNP A2. ComBio 99, Conrad Jupiters, Gold Coast, 27-30 September, 1999. Kent Town, SA: Aust. Society for Biochemistry & Molecular Biology.
Mouland, A. J., Xu, H., Mercier, J., Cui, H., Munro, T., Prasol, M., Smith, R. W., Barbarese, E., Cohen, E. and Carson, J. H. (1999). Co-trafficking of HIV-1 VPR and Gag RNA in Oligodendrocytes. AIDS Conference, New York, June, 1999.
Thesis
Munro, Trent Phillip (2001). A2RE-mediated RNA transport. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland. doi: 10.14264/uql.2020.832
Patents
Gray, Peter, Monteiro, Michael John, Munro, Trent Phillip and Prowse, Andrew Benjamin James (2013). Release Media. US9587104.