Dr Hannah Leeson
Postdoctoral Research Fellow
Australian Institute for Bioengineering and Nanotechnology
| Featured projects | Duration |
|---|---|
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Automated single cell quantitative in situ gene expression in cells and tissues (AutoMerFISH) Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
Journal Articles
Leeson, Hannah C., Aguado, Julio, Gómez-Inclán, Cecilia, Chaggar, Harman Kaur, Fard, Atefah Taherian, Hunter, Zoe, Lavin, Martin F., Mackay-Sim, Alan and Wolvetang, Ernst J. (2024). Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress. Neurobiology of Disease, 199 106562, 106562. doi: 10.1016/j.nbd.2024.106562
Chowdhury, Mohammad Mahfuz, Zimmerman, Samuel, Leeson, Hannah, Nefzger, Christian Maximilian, Mar, Jessica Cara, Laslett, Andrew, Polo, Jose Maria, Wolvetang, Ernst and Cooper-White, Justin (2024). Superior induced pluripotent stem cell generation through Phactr-3-driven mechano-modulation of both early and late phases of cell reprogramming. Biomaterials Research, 28 0025, 0025. doi: 10.34133/bmr.0025
Taherian Fard, Atefeh, Leeson, Hannah C., Aguado, Julio, Pietrogrande, Giovanni, Power, Dominique, Gómez-Inclán, Cecilia, Zheng, Huiwen, Nelson, Christopher B., Soheilmoghaddam, Farhad, Glass, Nick, Dharmaratne, Malindrie, Watson, Ebony R., Lu, Jennifer, Martin, Sally, Pickett, Hilda A., Cooper-White, Justin, Wolvetang, Ernst J. and Mar, Jessica C. (2023). Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution. GeroScience, 46 (1), 1-17. doi: 10.1007/s11357-023-00829-y
Leeson, Hannah C., Goh, Denise, Coman, David and Wolvetang, Ernst J. (2022). Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations. Stem Cell Research, 64 102917, 1-5. doi: 10.1016/j.scr.2022.102917
Aguado, Julio, Gómez-Inclán, Cecilia, Leeson, Hannah C., Lavin, Martin F., Shiloh, Yosef and Wolvetang, Ernst J. (2022). The hallmarks of aging in ataxia-telangiectasia. Ageing Research Reviews, 79 101653, 1-15. doi: 10.1016/j.arr.2022.101653
Hunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2022). Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening. Stem Cell Research, 60 102673, 102673. doi: 10.1016/j.scr.2022.102673
Shaker, Mohammed R., Kahtan, Amna, Prasad, Renuka, Lee, Ju-Hyun, Pietrogrande, Giovanni, Leeson, Hannah C., Sun, Woong, Wolvetang, Ernst J. and Slonchak, Andrii (2022). Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types. Frontiers in Cell and Developmental Biology, 10 803061, 803061. doi: 10.3389/fcell.2022.803061
Leeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Lavin, Martin F., Mackay-Sim, Alan and Wolvetang, Ernst J. (2021). Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations. Stem Cell Research, 56 102528, 102528. doi: 10.1016/j.scr.2021.102528
Leeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Mackay-Sim, Alan and Wolvetang, Ernst J. (2021). Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohort. Stem Cell Research, 56 102527, 102527. doi: 10.1016/j.scr.2021.102527
Hunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2021). Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients. Stem Cell Research, 56 102564, 102564. doi: 10.1016/j.scr.2021.102564
Aguado, Julio, Chaggar, Harman K., Gómez‐Inclán, Cecilia, Shaker, Mohammed R., Leeson, Hannah C., Mackay‐Sim, Alan and Wolvetang, Ernst J. (2021). Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids. Aging Cell, 20 (9) e13468, 1-16. doi: 10.1111/acel.13468
Ovchinnikov, Dmitry A., Withey, Sarah L., Leeson, Hannah C., Lei, U. Wang, Sundarrajan, Ashmitha, Junday, Keerat, Pewarchuk, Michelle, Yeo, Abrey J., Kijas, Amanda W., Lavin, Martin F. and Wolvetang, Ernst J. (2020). Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses. Human Molecular Genetics, 29 (6), 990-1001. doi: 10.1093/hmg/ddaa023
Leeson, Hannah, Chan-Ling, Tailoi, Lovelace, Michael, Brownlie, Jeremy, Gu, Ben and Weible, Michael (2019). P2X7 receptor signaling during adult hippocampal neurogenesis. Neural Regeneration Research, 14 (10), 1684-1694. doi: 10.4103/1673-5374.257510
Leeson, Hannah C., Chan-Ling, Tailoi, Lovelace, Michael D., Brownlie, Jeremy D., Weible, Michael W. and Gu, Ben J. (2019). Real-time live-cell flow cytometry to investigate calcium influx, pore formation, and phagocytosis by P2X7 receptors in adult neural progenitor cells. Journal of Visualized Experiments, 2019 (146) e59313, e59313. doi: 10.3791/59313
Leeson, Hannah C., Kasherman, Maria A., Chan-Ling, Tailoi, Lovelace, Michael D., Brownlie, Jeremy C., Toppinen, Kelly M., Gu, Ben J. and Weible, Michael W. (2018). P2X7 Receptors Regulate Phagocytosis and Proliferation in Adult Hippocampal and SVZ Neural Progenitor Cells: Implications for Inflammation in Neurogenesis. Stem Cells, 36 (11), 1764-1777. doi: 10.1002/stem.2894
Conference Paper
Withey, Sarah, Gerrard, Dave, Leeson, Hannah, Atkinson-Dell, Rebecca, Harrison, Sean, Baxter, Melissa, Al-Anbaki, Ali, Hanley, Karen Piper, Wolvetang, Ernst and Hanley., Neil (2020). Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytes. EASL: The Digital International Liver Congress, Online, 27-29 August 2020. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s0168-8278(20)31000-x