| Featured projects | Duration |
|---|---|
|
Understanding host-pathogen interactions through development of new co-transcriptomic single cell RNA sequencing technologies Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2020 |
Journal Articles
Duszyc, Kinga, von Pein, Jessica B., Ramnath, Divya, Currin-Ross, Denni, Verma, Suzie, Lim, Fayth, Sweet, Matthew J., Schroder, Kate and Yap, Alpha S. (2023). Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia. Developmental Cell, 58 (21), 2235-2248.e6. doi: 10.1016/j.devcel.2023.08.009
Chan, Amy H., Burgener, Sabrina S., Vezyrgiannis, Kassandra, Wang, Xiaohui, Acklam, Jadie, Von Pein, Jessica B., Pizzuto, Malvina, Labzin, Larisa I., Boucher, Dave and Schroder, Kate (2023). Caspase-4 dimerisation and D289 auto-processing elicit an
interleukin-1β-converting enzyme. Life Science Alliance, 6 (10) e202301908, 1-11. doi: 10.26508/lsa.202301908
Das Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B., Curson, James E. B., Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S., Murthy, Ambika M. V., Stocks, Claudia J., Kapetanovic, Ronan, Reid, Robert C., Iyer, Abishek, Ilka, Zoe C., Nauseef, William M., Plan, Manuel, Luo, Lin, Stow, Jennifer L., Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R., Schembri, Mark A., Fairlie, David P. and Sweet, Matthew J. (2023). HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences, 120 (4) e2212813120, 1-12. doi: 10.1073/pnas.2212813120
Ross, Connie, Chan, Amy H., von Pein, Jessica B., Maddugoda, Madhavi P., Boucher, Dave and Schroder, Kate (2022). Inflammatory caspases: toward a unified model for caspase activation by inflammasomes. Annual Review of Immunology, 40 (1), 249-269. doi: 10.1146/annurev-immunol-101220-030653
Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79 (1) 38, 38. doi: 10.1007/s00018-021-04041-z
Pein, Jessica B., Stocks, Claudia J., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2021). An alloy of zinc and innate immunity: galvanizing host defence against infection. Cellular Microbiology, 23 (1) e13268, 1-11. doi: 10.1111/cmi.13268
Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8), 2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007
Ross, Connie, Chan, Amy H., Von Pein, Jessica, Boucher, Dave and Schroder, Kate (2018). Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome. Life Science Alliance, 1 (6) e201800237, e201800237. doi: 10.26508/lsa.201800237
Chen, Kaiwen W., Monteleone, Mercedes, Boucher, Dave, Sollberger, Gabriel, Ramnath, Divya, Condon, Nicholas D., von Pein, Jessica B., Broz, Petr, Sweet, Matthew J. and Schroder, Kate (2018). Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps. Science Immunology, 3 (26) eaar6676, eaar6676. doi: 10.1126/sciimmunol.aar6676
Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2018). Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion. Cell Reports, 24 (6), 1425-1433. doi: 10.1016/j.celrep.2018.07.027
Chen, Kaiwen W., Lawlor, Kate E., von Pein, Jessica B., Boucher, Dave, Gerlic, Motti, Croker, Ben A., Bezbradica, Jelena S., Vince, James E and Schroder, Kate (2018). Cutting edge: blockade of inhibitor of apoptosis proteins sensitizes neutrophils to TNF- but not lipopolysaccharide-mediated cell death and IL-1β secretion. Journal of Immunology, 200 (10), 3341-3346. doi: 10.4049/jimmunol.1701620
Conference Paper
Haq, Sabah, Smith, Deandra R., von Pein, Jessica B., Sweet, Matthew J. and Knoell, Daren L. (2023). ZIP8 impacts protease activity in macrophages in response to Streptococcus pneumoniae. Immunology 2023 Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.162.03
Thesis
von Pein, Jessica Brooke (2023). Characterisation of the macrophage zinc toxicity response as an antimicrobial weapon. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/9491ac9