Dr Amanda Walker
Laboratory Coordinator/Research Assistant
School of Chemistry and Molecular Biosciences
| Featured projects | Duration |
|---|---|
|
Discovery of new regulatory networks with long-read transcriptomics Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
Book Chapter
Cole, J. N., Sanderson-Smith, M. L., Cork, A. J., Henningham, A., Conlan, F., Ranson, M., McArthur, J. D. and Walker, M. J. (2007). Gene expression and tagging of streptococcal proteins. Molecular Biology of Streptococci. (pp. 359-378) edited by Regine Hakenbeck and Singh Chhatwal. Norfold, United Kingdom: Horizon Bioscience.
Journal Articles
Richter, Johanna, Monteleone, Mercedes M, Cork, Amanda J., Barnett, Timothy C., Nizet, Victor, Brouwer, Stephan, Schroder, Kate and Walker, Mark J. (2021). Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection. Immunology and Cell Biology, 1-13. doi: 10.1111/imcb.12499
Loh, Jacelyn M. S., Rivera-Hernandez, Tania, McGregor, Reuben, Khemlani, Adrina Hema J., Tay, Mei Lin, Cork, Amanda J., M. Raynes, Jeremy, Moreland, Nicole J., Walker, Mark J. and Proft, Thomas (2021). A multivalent T-antigen-based vaccine for Group A Streptococcus. Scientific Reports, 11 (1) 4353, 1-10. doi: 10.1038/s41598-021-83673-4
Brouwer, Stephan, Barnett, Timothy C., Ly, Diane, Kasper, Katherine J., De Oliveira, David M. P., Rivera-Hernandez, Tania, Cork, Amanda J., McIntyre, Liam, Jespersen, Magnus G., Richter, Johanna, Schulz, Benjamin L., Dougan, Gordon, Nizet, Victor, Yuen, Kwok-Yung, You, Yuanhai, McCormick, John K., Sanderson-Smith, Martina L., Davies, Mark R. and Walker, Mark J. (2020). Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes. Nature Communications, 11 (1) 5018, 5018. doi: 10.1038/s41467-020-18700-5
De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791
Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2020). Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19). mBio, 11 (6) e02995-20, 1-1. doi: 10.1128/mBio.02995-20
Rivera-Hernandez, Tania, Rhyme, Mira Syahira, Cork, Amanda J., Jones, Scott, Segui-Perez, Celia, Brunner, Livia, Richter, Johanna, Petrovsky, Nikolai, Lawrenz, Maria, Goldblatt, David, Collin, Nicolas and Walker, Mark J. (2020). Vaccine-induced Th1-type response protects against invasive group A Streptococcus infection in the absence of opsonizing antibodies. mBio, 11 (2) e00122-20. doi: 10.1128/mbio.00122-20
Davies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (8), 1295-1295. doi: 10.1038/s41588-019-0482-z
Davies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (6), 1035-1043. doi: 10.1038/s41588-019-0417-8
Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2019). An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model. mBio, 10 (2) e00693-19. doi: 10.1128/mBio.00693-19
Walker, Mark J., Brouwer, Stephan, Forde, Brian M., Worthing, Kate A., McIntyre, Liam, Sundac, Lana, Maloney, Sam, Roberts, Leah W., Barnett, Timothy C., Richter, Johanna, Cork, Amanda J., Irwin, Adam D., You, Yuanhai, Zhang, Jianzhong, Dougan, Gordon, Yuen, K. Y., Nizet, Victor, Beatson, Scott A., Grimwood, Keith and Davies, Mark R. (2019). Detection of epidemic scarlet fever group A Streptococcus in Australia. Clinical Infectious Diseases, 69 (7), 1232-1234. doi: 10.1093/cid/ciz099
Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18
Brouwer, Stephan, Cork, Amanda J., Ong, Cheryl-Lynn Y., Barnett, Timothy C., West, Nicholas P., McIver, Kevin S. and Walker, Mark J. (2018). The endopeptidase PepO regulates the SpeB cysteine protease and is essential for the virulence of invasive M1T1 Streptococcus pyogenes. Journal of Bacteriology, 200 (8) e00654-17, e00654-17. doi: 10.1128/JB.00654-17
Rivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16
Cork, Amanda J., Ericsson, Daniel J., Law, Ruby H. P., Casey, Lachlan W., Valkov, Eugene, Bertozzi, Carlo, Stamp, Anna, Jovcevski, Blagojce, Aquilina, J. Andrew, Whisstock, James C., Walker, Mark J. and Kobe, Bostjan (2015). Stability of the octameric structure affects plasminogen-binding capacity of Streptococcal enolase. PLoS One, 10 (3) e0121764, 1-18. doi: 10.1371/journal.pone.0121764
Maamary, Peter G., Ben Zakour, Nouri L., Cole, Jason N., Hollands, Andrew, Aziz, Ramy K., Barnett, Timothy C., Cork, Amanda J., Henningham, Anna, Sanderson-Smith, Martina, McArthur, Jason D., Venturini, Carola, Gillen, Christine M., Kirk, Joshua K., Johnson, Dwight R., Taylor, William L., Kaplan, Edward L., Kotb, Malak, Nizet, Victor, Beatson, Scott A. and Walker, Mark J. (2012). Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. FASEB Journal, 26 (11), 4675-4684. doi: 10.1096/fj.12-212142
Henningham, Anna, Chiarot, Emiliano, Gillen, Christine M., Cole, Jason N., Rohde, Manfred, Fulde, Marcus, Ramachandran, Vidiya, Cork, Amanda J., Hartas, Jon, Magor, Graham, Djordjevic, Steven P., Cordwell, Stuart J., Kobe, Bostjan, Sriprakash, Kabada S., Nizet, Victor, Chhatwal, G. S., Margarit, Immaculada Y. R., Batzloff, Michael R. and Walker, Mark J. (2012). Conserved anchorless surface proteins as group A streptococcal vaccine candidates. Journal of Molecular Medicine, 90 (10), 1197-1207. doi: 10.1007/s00109-012-0897-9
Maamary, PG, Sanderson-Smith, ML, Aziz, RK, Hollands, A, Cole, JN, Mckay, FC, McArthur, JD, Kirk, JK, Cork, AJ, Keefe, RJ, Kansal, RG, Sun, H, Taylor, WL, Chhatwal, GS, Ginsburg, D, Nizet, V, Kotb, M and Walker, MJ (2010). Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. Journal of Innate Immunology, 2 (6), 596-606. doi: 10.1159/000317640
Cork, A. J., Jergic, S., Hammerschmidt, S., Kobe, B., Pancholi, V., Benesch, J. L. P., Robinson, C. V., Dixon, N. E., Aquilina, J. A. and Walker, M. J. (2009). Defining the structural basis of human plasminogen binding by streptococcal surface enolase. Journal of Biological Chemistry, 284 (25), 17129-17137. doi: 10.1074/jbc.M109.004317
McArthur, Jason D., McKay, Fiona C., Ramachandran, Vidiya, Shyam, Priya, Cork, Amanda J., Sanderson-Smith, Martina L., Cole, Jason N., Ringdahl, Ulrika, Sjobring, Ulf, Ranson, Marie and Walker, Mark J. (2008). Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation. Faseb Journal, 22 (9), 3146-3153. doi: 10.1096/fj.08-109348
Sanderson-Smith, M. L., Dinkla, K., Cole, J. N., Cork, A. J., Maamary, P. G., McArthur, J. D., Chhatwal, G. S. and Walker, M. J. (2008). M protein-mediated plasminogen binding is essential for the virulence of an invasive Streptococcus pyogenes isolate. The FASEB Journal, 22 (8), 2715-2722. doi: 10.1096/fj.07-105643
Cole, Jason N., McArthur, Jason D., McKay, Fiona C., Sanderson-Smith, Martina L., Cork, Amanda J., Ranson, Marie, Rohde, Manfred, Itzek, Andreas, Sun, Hongmin, Ginsburg, David, Kotb, Malak, Nizet, Victor, Chhatwal, GS and Walker, Mark J. (2006). Trigger for group A streptococcal M1T1 invasive disease. FASEB Journal, 20 (10), E1139-E1145. doi: 10.1096/fj.06-5804fje