Associate Professor Jessica Mar
ARC Future Fellow
Australian Institute for Bioengineering and Nanotechnology (AIBN)
Affiliate Research Fellow
Institute for Molecular Bioscience (IMB)
Researcher biography
Qualifications
- Doctor of Philosophy, Harvard University
| Featured projects | Duration |
|---|---|
|
Automated single cell quantitative in situ gene expression in cells and tissues (AutoMerFISH) Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2019 |
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Expanding the scope of multimodal single cell sequencing Genome Innovation Hub Collaborative Project (UQ infrastructure) |
2021 |
Journal Articles
Ren, Zuen, Dharmaratne, Malindrie, Liang, Huizhi, Benard, Outhiriaradjou, Morales-Gallego, Miriam, Suyama, Kimita, Kumar, Viney, Fard, Atefeh Taherian, Kulkarni, Ameya S., Prystowsky, Michael, Mar, Jessica C., Norton, Larry and Hazan, Rachel B. (2024). Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α. British Journal of Cancer, 130 (6), 908-924. doi: 10.1038/s41416-023-02522-5
Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C. ... Wolvetang, Ernst J. (2023). Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging, 3 (12), 1-15. doi: 10.1038/s43587-023-00519-6
Zheng, Huiwen, Vijg, Jan, Fard, Atefeh Taherian and Mar, Jessica Cara (2023). Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging. Genome Biology, 24 (1) 238, 1-26. doi: 10.1186/s13059-023-03036-2
Taherian Fard, Atefeh, Leeson, Hannah C., Aguado, Julio, Pietrogrande, Giovanni, Power, Dominique, Gómez-Inclán, Cecilia, Zheng, Huiwen, Nelson, Christopher B., Soheilmoghaddam, Farhad, Glass, Nick, Dharmaratne, Malindrie, Watson, Ebony R., Lu, Jennifer, Martin, Sally, Pickett, Hilda A., Cooper-White, Justin, Wolvetang, Ernst J. and Mar, Jessica C. (2023). Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution. GeroScience, 46 (1), 1-17. doi: 10.1007/s11357-023-00829-y
Dharmaratne, Malindrie, Kulkarni, Ameya S., Taherian Fard, Atefeh and Mar, Jessica C. (2023). scShapes: a statistical framework for identifying distribution shapes in single-cell RNA-sequencing data. GigaScience, 12 giac126, 1-18. doi: 10.1093/gigascience/giac126
Ho, Joshua W. K., Chen, Xi, He, Mu, Huang, Yuanhua, Mar, Jessica C., Shih, David J. H. and Wu, Angela R. (2022). Biophysical Reviews special issue call: quantitative methods to decipher cellular heterogeneity — from single-cell to spatial omic methods. Biophysical Reviews, 14 (5), 1079-1080. doi: 10.1007/s12551-022-00994-y
Watson, Ebony Rose, Mora, Ariane, Taherian Fard, Atefeh and Mar, Jessica Cara (2022). How does the structure of data impact cell–cell similarity? Evaluating how structural properties influence the performance of proximity metrics in single cell RNA-seq data. Briefings in Bioinformatics, 23 (6), 1-14. doi: 10.1093/bib/bbac387
Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5
Ren, Zuen, Liang, Huizhi, Galbo, Phillip M., Dharmaratne, Malindrie, Kulkarni, Ameya S., Fard, Atefeh Taherian, Aoun, Marie Louise, Martinez-Lopez, Nuria, Suyama, Kimita, Benard, Outhiriaradjou, Zheng, Wei, Liu, Yang, Albanese, Joseph, Zheng, Deyou, Mar, Jessica C., Singh, Rajat, Prystowsky, Michael B., Norton, Larry and Hazan, Rachel B. (2022). Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. Proceedings of the National Academy of Sciences, 119 (8) e2107266119. doi: 10.1073/pnas.2107266119
Watson, Ebony Rose, Taherian Fard, Atefeh and Mar, Jessica Cara (2022). Computational methods for single-cell imaging and omics data integration. Frontiers in Molecular Biosciences, 8 768106, 768106. doi: 10.3389/fmolb.2021.768106
Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2021). Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nature Communications, 12 (1) 3297. doi: 10.1038/s41467-021-23143-7
de Torrente, Laurence, Zimmerman, Samuel, Suzuki, Masako, Christopeit, Maximilian, Greally, John M. and Mar, Jessica C. (2020). The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data. BMC Bioinformatics, 21 (Suppl 21) 562, 562. doi: 10.1186/s12859-020-03892-w
Lu, Tianyuan and Mar, Jessica C. (2020). Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types. Biology of Sex Differences, 11 (1) 61, 61. doi: 10.1186/s13293-020-00335-2
Yu, Bo, Doni Jayavelu, Naresh, Battle, Stephanie L., Mar, Jessica C., Schimmel, Timothy, Cohen, Jacques and Hawkins, R. David (2020). Single-cell analysis of transcriptome and DNA methylome in human oocyte maturation. PLoS One, 15 (11) e0241698, e0241698. doi: 10.1371/journal.pone.0241698
Kulkarni, Ameya S., Peck, Bailey D., Walton, R. Grace, Kern, Philip A., Mar, Jessica C., Windham, Samuel T., Bamman, Marcas M., Barzilai, Nir and Peterson, Charlotte A. (2020). Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults. Aging, 12 (20), 19852-19866. doi: 10.18632/aging.104096
Piqué, Daniel G., Greally, John M. and Mar, Jessica C. (2020). Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival. BMC Cancer, 20 (1) 857, 857. doi: 10.1186/s12885-020-07325-y
Ratnakumar, Abhirami, Weinhold, Nils, Mar, Jessica C. and Riaz, Nadeem (2020). Protein-protein interactions uncover candidate 'core genes' within omnigenic disease networks. PLoS Genetics, 16 (7) e1008903, e1008903. doi: 10.1371/journal.pgen.1008903
Wei, Qiaozhi, Nakahara, Fumio, Asada, Noboru, Zhang, Dachuan, Gao, Xin, Xu, Chunliang, Alfieri, Alan, Brodin, N. Patrik, Zimmerman, Samuel E., Mar, Jessica C., Guha, Chandan, Guo, Wenjun and Frenette, Paul S. (2020). Snai2 maintains bone marrow niche cells by repressing osteopontin expression. Developmental Cell, 53 (5), 503-513. doi: 10.1016/j.devcel.2020.04.012
Andriani, Grasiella A., Maggi, Elaine, Piqué, Daniel, Zimmerman, Samuel E., Lee, Moonsook, Quispe-Tintaya, Wilber, Maslov, Alexander, Campisi, Judith, Vijg, Jan, Mar, Jessica C. and Montagna, Cristina (2019). A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses. Scientific Reports, 9 (1) 10508, 10508. doi: 10.1038/s41598-019-46606-w
Piqué, Daniel G., Andriani, Grasiella A., Maggi, Elaine, Zimmerman, Samuel E., Greally, John M., Montagna, Cristina and Mar, Jessica C. (2019). Aneuvis: web-based exploration of numerical chromosomal variation in single cells. BMC Bioinformatics, 20 (1) 336, 336. doi: 10.1186/s12859-019-2842-1
Raman, Pichai, Zimmerman, Samuel, Rathi, Komal S., de Torrenté, Laurence, Sarmady, Mahdi, Wu, Chao, Leipzig, Jeremy, Taylor, Deanne M., Tozeren, Aydin and Mar, Jessica C. (2019). A comparison of survival analysis methods for cancer gene expression RNA-Sequencing data. Cancer Genetics, 235-236, 1-12. doi: 10.1016/j.cancergen.2019.04.004
Taylor, Deanne M., Aronow, Bruce J., Tan, Kai, Bernt, Kathrin, Salomonis, Nathan, Greene, Casey S., Frolova, Alina, Henrickson, Sarah E., Wells, Andrew, Pei, Liming, Jaiswal, Jyoti K., Whitsett, Jeffrey, Hamilton, Kathryn E., MacParland, Sonya A., Kelsen, Judith, Heuckeroth, Robert O., Potter, S. Steven, Vella, Laura A., Terry, Natalie A., Ghanem, Louis R., Kennedy, Benjamin C., Helbig, Ingo, Sullivan, Kathleen E., Castelo-Soccio, Leslie, Kreigstein, Arnold, Herse, Florian, Nawijn, Martijn C., Koppelman, Gerard H., Haendel, Melissa ... White, Peter S. (2019). The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution. Developmental Cell, 49 (1), 10-29. doi: 10.1016/j.devcel.2019.03.001
Mar, Jessica C. (2019). The rise of the distributions: why non-normality is important for understanding the transcriptome and beyond. Biophysical Reviews, 11 (1), 89-94. doi: 10.1007/s12551-018-0494-4
Piqué, Daniel G., Montagna, Cristina, Greally, John M. and Mar, Jessica C. (2019). A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma. British Journal of Cancer, 120 (7), 746-753. doi: 10.1038/s41416-019-0387-8
Ratnakumar, Abhirami, Zimmerman, Samuel E., Jordan, Bryen A. and Mar, Jessica C. (2019). Estrogen activates Alzheimer's disease genes. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 5 (C), 906-917. doi: 10.1016/j.trci.2019.09.004
Xu, Chunliang, Gao, Xin, Wei, Qiaozhi, Nakahara, Fumio, Zimmerman, Samuel E., Mar, Jessica and Frenette, Paul S. (2018). Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nature Communications, 9 (1) 2449. doi: 10.1038/s41467-018-04726-3
Boulais, Philip E., Mizoguchi, Toshihide, Zimmerman, Samuel, Nakahara, Fumio, Vivie, Judith, Mar, Jessica C., van Oudenaarden, Alexander and Frenette, Paul S. (2018). The majority of CD45- Ter119- CD31- bone marrow cell fraction is of hematopoietic origin and contains erythroid and lymphoid progenitors. Immunity, 49 (4), 627-639. doi: 10.1016/j.immuni.2018.2018.08.019
Chen, Shuonan and Mar, Jessica C. (2018). Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data. BMC Bioinformatics, 19 (1) 232, 232. doi: 10.1186/s12859-018-2217-z
Kulkarni, Ameya S., Brutsaert, Erika F., Anghel, Valentin, Zhang, Kehao, Bloomgarden, Noah, Pollak, Michael, Mar, Jessica C., Hawkins, Meredith, Crandall, Jill P. and Barzilai, Nir (2018). Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. Aging Cell, 17 (2) e12723, e12723. doi: 10.1111/acel.12723
Bueno, Raymund and Mar, Jessica C. (2017). Changes in gene expression variability reveal a stable synthetic lethal interaction network in BRCA2-ovarian cancers. Methods, 131, 74-82. doi: 10.1016/j.ymeth.2017.07.021
de Torrente, Laurence, Zimmerman, Samuel, Taylor, Deanne, Hasegawa, Yu, Wells, Christine A. and Mar, Jessica C. (2017). pathVar: a new method for pathway-based interpretation of gene expression variability. PeerJ, 2017 (5) e3334, e3334. doi: 10.7717/peerj.3334
Ito, Kyoko, Turcotte, Raphaël, Cui, Jinhua, Zimmerman, Samuel E., Pinho, Sandra, Mizoguchi, Toshihide, Arai, Fumio, Runnels, Judith M., Alt, Clemens, Teruya-Feldstein, Julie, Mar, Jessica C., Singh, Rajat, Suda, Toshio, Lin, Charles P., Frenette, Paul S. and Ito, Keisuke (2016). Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance. Science, 354 (6316), 1156-1160. doi: 10.1126/science.aaf5530
Taherian Fard, Atefeh, Srihari, Sriganesh, Mar, Jessica C. and Ragan, Mark A. (2016). Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks. NPJ Systems Biology and Applications, 2 (1) 16001, 16001. doi: 10.1038/npjsba.2016.1
Hurst, Laurence D., Ghanbarian, Avazeh T., Forrest, Alistair R. R., Huminiecki, Lukasz, Rehli, Michael, Baillie, J. Kenneth, de Hoon, Michiel J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicolas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S. ... Hayashizaki, Yoshihide (2015). The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome. PLoS Biology, 13 (12) e1002315, e1002315. doi: 10.1371/journal.pbio.1002315
Carbajo, Daniel, Magi, Shigeyuki, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Arner, Erik, Forrest, Alistair R. R., Carninci, Piero, Hayashizaki, Yoshihide, Daub, Carsten O., Okada-Hatakeyama, Mariko and Mar, Jessica C. (2015). Application of gene expression trajectories initiated from ErbB receptor activation highlights the dynamics of divergent promoter usage. Plos One, 10 (12) e0144176, e0144176. doi: 10.1371/journal.pone.0144176
Hasegawa, Yu., Taylor, Deanne., Ovchinnikov, Dmitry A., Wolvetang, Ernst J., de Torrente, Laurence. and Mar, Jessica C. (2015). Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. PLoS Genetics, 11 (8) e1005428, e1005428. doi: 10.1371/journal.pgen.1005428
Tonge, Peter D., Corso, Andrew J., Monetti, Claudio, Hussein, Samer M. I., Puri, Mira C., Michael, Iacovos P., Li, Mira, Lee, Dong-Sung, Mar, Jessica C., Cloonan, Nicole, Wood, David L., Gauthier, Maely E., Korn, Othmar, Clancy, Jennifer L., Preiss, Thomas, Grimmond, Sean M., Shin, Jong-Yeon, Seo, Jeong-Sun, Wells, Christine A., Rogers, Ian M. and Nagy, Andras (2015). Erratum: Divergent reprogramming routes lead to alternative stem-cell states (Nature (2014) 516 (192-197) DOI: 10.1038/nature14047). Nature, 523 (7562), 626-626. doi: 10.1038/nature14607
Hussein, Samer M. I., Puri, Mira C., Tonge, Peter D., Benevento, Marco, Corso, Andrew J., Clancy, Jennifer L., Mosbergen, Rowland, Li, Mira, Lee, Dong-Sung, Cloonan, Nicole, Wood, David L. A., Munoz, Javier, Middleton, Robert, Korn, Othmar, Patel, Hardip R., White, Carl A., Shin, Jong-Yeon, Gauthier, Maely E., Le Cao, Kim-Anh, Kim, Jong-Il, Mar, Jessica C., Shakiba, Nika, Ritchie, William, Rasko, John E. J., Grimmond, Sean M., Zandstra, Peter W., Wells, Christine A., Preiss, Thomas, Seo, Jeong-Sun ... Nagy, Andras (2015). Corrigendum: Genome-wide characterization of the routes to pluripotency. Nature, 523 (7562), 626-626. doi: 10.1038/nature14606
Ramachandiran, Sampath, Adon, Arsene, Guo, Xiangxue, Wang, Yi, Wang, Huichen, Chen, Zhengjia, Kowalski, Jeanne, Sunay, Ustun R., Young, Andrew N., Brown, Theresa, Mar, Jessica C., Du, Yuhong, Fu, Haian, Mann, Karen P., Natkunam, Yasodha, Boise, Lawrence H., Saavedra, Harold I., Lossos, Izidore S. and Bernal-Mizrachi, Leon (2015). Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway. International Journal of Cancer, 136 (10), 2341-2351. doi: 10.1002/ijc.29301
Li, Wenge, Calder, R. Brent, Mar, Jessica C. and Vijg, Jan (2015). Single-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated alleles. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 772, 55-62. doi: 10.1016/j.mrfmmm.2015.01.002
Tonge, Peter D., Corso, Andrew J., Monetti, Claudio, Hussein, Samer M. I., Puri, Mira C., Michael, Iacovos P., Li, Mira, Lee, Dong-Sung, Mar, Jessica C., Cloonan, Nicole, Wood, David L., Gauthier, Maely E., Korn, Othmar, Clancy, Jennifer L., Preiss, Thomas, Grimmond, Sean M., Shin, Jong-Yeon, Seo, Jeong-Sun, Wells, Christine A., Rogers, Ian M. and Nagy, Andras (2014). Divergent reprogramming routes lead to alternative stem-cell states. Nature, 516 (7530), 192-197. doi: 10.1038/nature14047
Hussein, Samer M. I., Puri, Mira C., Tonge, Peter D., Benevento, Marco, Corso, Andrew J., Clancy, Jennifer L., Mosbergen, Rowland, Li, Mira, Lee, Dong-Sung, Cloonan, Nicole, Wood, David L. A., Munoz, Javier, Middleton, Robert, Korn, Othmar, Patel, Hardip R., White, Carl A., Shin, Jong-Yeon, Gauthier, Maely E., Le Cao, Kim-Anh, Kim, Jong-Il, Mar, Jessica C., Shakiba, Nika, Ritchie, William, Rasko, John E. J., Grimmond, Sean M., Zandstra, Peter W., Wells, Christine A., Preiss, Thomas, Seo, Jeong-Sun ... Nagy, Andras (2014). Genome-wide characterization of the routes to pluripotency. Nature, 516 (7530), 198-+. doi: 10.1038/nature14046
Wijetunga, N. Ari, Delahaye, Fabien, Zhao, Yong M., Golden, Aaron, Mar, Jessica C., Einstein, Francine H. and Greally, John M. (2014). The meta-epigenomic structure of purified human stem cell populations is defined at cis-regulatory sequences. Nature Communications, 5 (1) 6195. doi: 10.1038/ncomms6195
Mason, Elizabeth, Mar, Jessica C., Laslett, Andrew, Pera, Martin F., Quackenbush, John, Wolvetang, Ernst and Wells C. (2014). Gene expression variability as a unifying element of the pluripotency network. Stem Cell Reports, 3 (2), 365-377. doi: 10.1016/j.stemcr.2014.06.008
Hough, Shelley R., Thornton, Matthew, Mason, Elizabeth, Mar, Jessica C., Wells, Christine A. and Pera, Martin F. (2014). Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells. Stem Cell Reports, 2 (6), 881-895. doi: 10.1016/j.stemcr.2014.04.014
Mukhopadhyay, Rituparna, Lajugie, Julien, Fourel, Nicolas, Selzer, Ari, Schizas, Michael, Bartholdy, Boris, Mar, Jessica, Lin, Chii Mei, Martin, Melvenia M., Ryan, Michael, Aladjem, Mirit I. and Bouhassira, Eric E. (2014). Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization. PLoS Genetics, 10 (5) e1004319, e1004319. doi: 10.1371/journal.pgen.1004319
Forest, Alistair R. R., Kawaji, Hideya, Rehli, Michael, Baillie, J. Kenneth, De Hoon, Michael J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicholas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S., Francescatto, Margherita, Altschuler, Intikhab ... Hayashizaki, Yoshihide (2014). A promoter-level mammalian expression atlas. Nature, 507 (7493), 462-470. doi: 10.1038/nature13182
Goto, Derek B., Miyazawa, Hikota, Mar, Jessica C. and Sato, Masanao (2013). Not to be suppressed?: rethinking the host response at a root-parasite interface. Plant Science, 213, 9-17. doi: 10.1016/j.plantsci.2013.08.004
Kunisaki, Yuya, Bruns, Ingmar, Scheiermann, Christoph, Ahmed, Jalal, Pinho, Sandra, Zhang, Dachuan, Mizoguchi, Toshihide, Wei, Qiaozhi, Lucas, Daniel, Ito, Keisuke, Mar, Jessica C., Bergman, Aviv and Frenette, Paul S. (2013). Arteriolar niches maintain haematopoietic stem cell quiescence. Nature, 502 (7473), 637-643. doi: 10.1038/nature12612
Kouno, Tsukasa, de Hoon, Michiel, Mar, Jessica C., Tomaru, Yasuhiro, Kawano, Mitsuoki, Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide and Shin, Jay W. (2013). Temporal dynamics and transcriptional control using single-cell gene expression analysis. Genome Biology, 14 (10) R118. doi: 10.1186/gb-2013-14-10-r118
Rozenblatt-Rosen, Orit, Deo, Rahul C., Padi, Megha, Adelmant, Guillaume, Calderwood, Michael A., Rolland, Thomas, Grace, Miranda, Dricot, Amélie, Askenazi, Manor, Tavares, Maria, Pevzner, Samuel J., Abderazzaq, Fieda, Byrdsong, Danielle, Carvunis, Anne-Ruxandra, Chen, Alyce A., Cheng, Jingwei, Correll, Mick, Duarte, Melissa, Fan, Changyu, Feltkamp, Mariet C., Ficarro, Scott B., Franchi, Rachel, Garg, Brijesh K., Gulbahce, Natali, Hao, Tong, Holthaus, Amy M., James, Robert, Korkhin, Anna, Litovchick, Larisa ... Vidal, Marc (2012). Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature, 487 (7408), 491-495. doi: 10.1038/nature11288
Nayler, Sam, Gatei, Magtouf, Kozlov, Sergei, Gatti, Richard, Mar, Jessica C., Wells, Christine A., Lavin, Martin and Wolvetang, Ernst (2012). Induced Pluripotent Stem Cells from Ataxia-Telangiectasia Recapitulate the Cellular Phenotype. Stem Cells Translational Medicine, 1 (7), 523-535. doi: 10.5966/sctm.2012-0024
Gulbahce, Natali, Yan, Han, Dricot, Amélie, Padi, Megha, Byrdsong, Danielle, Franchi, Rachel, Lee, Deok-Sun, Rozenblatt-Rosen, Orit, Mar, Jessica C., Calderwood, Michael A., Baldwin, Amy, Zhao, Bo, Santhanam, Balaji, Braun, Pascal, Simonis, Nicolas, Huh, Kyung-Won, Hellner, Karin, Grace, Miranda, Chen, Alyce, Rubio, Renee, Marto, Jarrod A., Christakis, Nicholas A., Kieff, Elliott, Roth, Frederick P., Roecklein-Canfield, Jennifer, DeCaprio, James A., Cusick, Michael E., Quackenbush, John, Hill, David E. ... Barabási, Albert-László (2012). Viral perturbations of host networks reflect disease etiology. PLoS Computational Biology, 8 (6) e1002531, e1002531. doi: 10.1371/journal.pcbi.1002531
Chittenden, Thomas W., Howe, Eleanor A., Taylor, Jennifer M., Mar, Jessica C., Aryee, Martin J., Gómez, Harold, Sultana, Razvan, Braisted, John, Nair, Sarita J., Quackenbush, John and Holmes, Chris (2012). nEASE: a method for gene ontology subclassification of high-throughput gene expression data. Bioinformatics, 28 (5) bts011, 726-728. doi: 10.1093/bioinformatics/bts011
Gewurz, Benjamin E., Towfic, Fadi, Mar, Jessica C., Shinners, Nicholas P., Takasaki, Kaoru, Zhao, Bo, Cahir-McFarland, Ellen D., Quackenbush, John, Xavier, Ramnik J. and Kieff, Elliott (2012). Genome-wide siRNA screen for mediators of NF-κB activation. Proceedings of the National Academy of Sciences of the United States of America, 109 (7), 2467-2472. doi: 10.1073/pnas.1120542109
Mar, Jessica C., Matigian, Nicholas A., Quackenbush, John and Wells, Christine A. (2011). Attract : A method for identifying core pathways that define cellular phenotypes. PLoS One, 6 (10 Article # e25445) e25445, e25445-1-e25445-6. doi: 10.1371/journal.pone.0025445
Zhao, Bo, Zou, James, Wang, Hongfang, Johannsen, Eric, Peng, Chih-Wen, Quackenbush, John, Mar, Jessica C., Morton, Cynthia Casson, Freedman, Matthew L., Blacklow, Stephen C., Aster, Jon C., Bernstein, Bradley E. and Kieff, Elliott (2011). Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. Proceedings of the National Academy of Sciences of the United States of America, 108 (36), 14902-14907. doi: 10.1073/pnas.1108892108
Mar, Jessica C., Matigian, Nicholas A., Mackay-Sim, Alan, Mellick, George D., Sue, Carolyn M., Silburn, Peter A., McGrath, John J., Quackenbush, John and Wells, Christine A. (2011). Variance of gene expression identifies altered network constraints in neurological disease. PLoS Genetics, 7 (8) e1002207, e1002207. doi: 10.1371/journal.pgen.1002207
Gewurz, Benjamin E., Mar, Jessica C., Padi, Megha, Zhao, Bo, Shinners, Nicholas P., Takasaki, Kaoru, Bedoya, Edward, Zou, James Y., Cahir-Mcfarland, Ellen, Quackenbush, John and Kieff, Elliott (2011). Canonical NF-κB activation is essential for Epstein-Barr virus latent membrane protein 1 TES2/CTAR2 gene regulation. Journal of Virology, 85 (13), 6764-6773. doi: 10.1128/JVI.00422-11
Mar, Jessica C., Wells, Christine A. and Quackenbush, John (2011). Defining an informativeness metric for clustering gene expression data. Bioinformatics, 27 (8) btr074, 1094-1100. doi: 10.1093/bioinformatics/btr074
Zhao, Bo, Mar, Jessica C., Maruo, Seiji, Lee, Sungwook, Gewurz, Benjamin E., Johannsen, Eric, Holton, Kristina, Rubio, Renee, Takada, Kenzo, Quackenbush, John and Kieff, Elliott (2011). Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines. Proceedings of the National Academy of Sciences, 108 (1), 337-342. doi: 10.1073/pnas.1017419108
Chittenden, Thomas W., Pak, Jane, Rubio, Renee, Cheng, Hailing, Holton, Kristina, Prendergast, Niall, Glinskii, Vladimir, Cai, Yi, Culhane, Aedin, Bentink, Stefan, Schwede, Mathew, Mar, Jessica C., Howe, Eleanor A., Aryee, Martin, Sultana, Razvan, Lanahan, Anthony A., Taylor, Jennifer M., Holmes, Chris, Hahn, William C., Zhao, Jean J., Iglehart, J. Dirk and Quackenbush, John (2010). Therapeutic implications of GIPC1 silencing in cancer. PLoS ONE, 5 (12) e15581, e15581. doi: 10.1371/journal.pone.0015581
Mar, Jessica C. and Quackenbush, John (2009). Decomposition of gene expression state space trajectories. PLoS Computational Biology, 5 (12) e1000626. doi: 10.1371/journal.pcbi.1000626
Hellner, Karin, Mar, Jessica, Fang, Frank, Quackenbush, John and Münger, Karl (2009). HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition. Virology, 391 (1), 57-63. doi: 10.1016/j.virol.2009.05.036
Suzuki, H, Forrest, ARR, van Nimwegen, E, Daub, CO, Balwierz, PJ, Irvine, KM, Lassmann, T, Ravasi, T, Hasegawa, Y, de Hoon, MJL, Katayama, S, Schroder, K, Carninci, P, Tomaru, Y, Kanamori-Katayama, M, Kubosaki, A, Akalin, A, Ando, Y, Arner, E, Asada, M, Asahara, H, Bailey, T, Bajic, VB, Bauer, D, Beckhouse, AG, Bertin, N, Bjorkegren, J, Brombacher, F, Bulger, E ... Riken Omics Science Center (2009). The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics, 41 (5), 553-562. doi: 10.1038/ng.375
Mar, Jessica C., Kimura, Yasumasa, Schroder, Kate, Irvine, Katherine M., Hayashizaki, Yoshihide, Suzuki, Harukazu, Hume, David and Quackenbush, John (2009). Data-driven normalization strategies for high-throughput quantitative RT-PCR. BMC Bioinformatics, 10 (1) 110, 110.1-110.10. doi: 10.1186/1471-2105-10-110
Silver, Daniel P., Dimitrov, Stoil D., Feunteun, Jean, Gelman, Rebecca, Drapkin, Ronny, Lu, Shihua D., Shestakova, Elena, Velmurugan, Soundarapandian, DeNunzio, Nicholas, Dragomir, Serban, Mar, Jessica, Liu, Xiaoling, Rottenberg, Sven, Jonkers, Jos, Ganesan, Shridar and Livingston, David M. (2007). Further Evidence for BRCA1 Communication with the Inactive X Chromosome. Cell, 128 (5), 991-1002. doi: 10.1016/j.cell.2007.02.025
Mar, Jessica C., Rubio, Renee and Quackenbush, John (2006). Inferring steady state single-cell gene expression distributions from analysis of mesoscopic samples. Genome Biology, 7 (12) R119. doi: 10.1186/gb-2006-7-12-r119
Haas, David W., Geraghty, Daniel E., Andersen, Janet, Mar, Jessica, Motsinger, Alison A., D'Aquila, Richard T., Unutmaz, Derya, Benson, Constance A., Ritchie, Marylyn D. and Landay, Alan (2006). Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS clinical trials group study. Journal of Infectious Diseases, 194 (8), 1098-1107. doi: 10.1086/507313
Mar, Jessica C., Harlow, Timothy J . and Ragan, Mark A. (2005). Bayesian and maximum likelihood phylogenetic analyses of protein sequence data under relative branch-length differences and model violation. BMC Evolutionary Biology, 5 (1), 8.1-8.20. doi: 10.1186/1471-2148-5-8
Mar, J.C. and McLachlan, G.J. (2003). Model-based clustering in gene expression microarrays: an application to breast cancer data. International Journal of Software Engineering and Knowledge Engineering, 13 (6), 579-592. doi: 10.1142/S0218194003001482
Conference Papers
Cooper-White, Justin, Chowdhury, Mahfuz, Wolvetang, Ernst, Zimmerman, Samuel, Mar, Jessica, Polo, Jose, Laslett, Andrew and Nefzger, Christian (2022). Softer, faster, better! - Substrate mechanics drives superior somatic cell reprogramming outcomes. TERMIS 6th World Congress, Maastricht, Netherlands, 15-19 November 2021. New Rochelle, NY United States: Mary Ann Liebert.
Ren, Zuen, Dharmaratne, Malindrie, Kulkarni, Ameya, Fard, Atefeh Taherian, Mar, Jessica, Galbo, Phillip M., Liu, Yang, Zheng, Deyou, Liang, Huizhi, Benard, Outhiriaradjou, Suyama, Kimita, Prystowsky, Michael B., Norton, Larry and Hazan, Rachel B. (2020). Redox regulation of tumor cell heterogeneity in the PyMT mammary tumor model revealed by single cell RNA sequencing. AACR Annual Meeting, Online, 22-24 June, 2020. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2020-4426
Church, Benjamin V., Williams, Henry T. and Mar, Jessica C. (2019). Investigating skewness to understand gene expression heterogeneity in large patient cohorts. The International Conference on Intelligent Biology and Medicine (ICIBM 2019), Columbia, OH, United States, 9-11 June 2019. London, United Kingdom: BioMed Central. doi: 10.1186/s12859-019-3252-0