Expertise

  • Protein engineering
  • Mass spectrometry
  • Letivirus production

Researcher biography

Max has a research background in the fields of molecular and cellular biology with a focus on protein engineering. In 2012, he obtained his BSc from the University of Wollongong before moving to Victoria and completing a 1st Class honours degree at Monash University in 2014. He then moved to Queensland, successfully completing his PhD at Griffith Institute for Drug Discovery in 2018. During his PhD he secured the opportunity to embark on an overseas exchange at iHuman Institute, Shanghai Tech University in China, enhancing his molecular and cell biology expertise with a sound knowledge of Chemistry.

Since coming to GIH, Max's focus is to optimise highly efficient, scalable, precise genome editing. His knowledge of protein expression and purification has facilitated rapid progress in his aim of producing native Cas9 in addition to several recombinant Cas9 fusion proteins. One of these recombinant variants, Cas9/SNAP-tag fusion, necessitates covalently binding of engineered O6-benzylguanine (BG)-labelled repair templates to the SNAP-tagged recombinant Cas9 fusion protein, thus allowing Max to couple his protein expression proficiency with his sound chemical expertise.

Featured projects Duration
Using nanopore sequencing to test mRNA vaccine quality.
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2022
Division-based single-cell-sequencing
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2022
Multi-contact Pore-C
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2022
Identification and exploitation of genome landing pads for cattle.
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2022
Enrichment and analysis of siRNAs for topical RNAi applications.
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2022
Ribosomal profiling with cellular specificity
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2023
Precise genome editing
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Proximity ligation sequencing of mixed bacterial communities
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2023
Using transposon-sequencing to probe whole cell protein-protein interactions
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Cas9 targeted enrichment for Nanopore sequencing
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2023
Automated single cell quantitative in situ gene expression in cells and tissues (AutoMerFISH)
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
OmniCRISPR: a simultaneous and combinatorial approach to the generation of multiple precise genomic alterations
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Simultaneous identification of RNA-chromatin interactions and transcriptomes in single cells
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Dual gRNA screen
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Optimised bioinformatics and validation pipeline for genome-wide CRISPR screening data
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Genome-Phaser: protocol for fully phasing whole genome variants using haplotagging
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Expanding the scope of multimodal single cell sequencing
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
HTS single cell CRISPR technology for experimental validation of population genetics and functional genomics discovery
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Enabling population scale epigenomics for crop improvement
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021