Professor Ian Henderson

Featured projects	Duration
Using transposon-sequencing to probe whole cell protein-protein interactions Genome Innovation Hub Collaborative Project (UQ infrastructure)	2019
TraDIS-Vault: an interactive searchable genome browser and repository for TraDIS data Genome Innovation Hub Collaborative Project (UQ infrastructure)	2020

Hodges, Freya J., Torres, Von Vergel L., Cunningham, Adam F., Henderson, Ian R. and Icke, Christopher (2023). Redefining the bacterial Type I protein secretion system. Advances in microbial physiology. (pp. 155-204) San Diego, CA, United States: Academic Press. doi: 10.1016/bs.ampbs.2022.10.003

Wells, Timothy J. and Henderson, Ian R. (2013). Type 1 and 5 secretion systems and associated toxins. Escherichia coli: pathotypes and principles of pathogenesis. (pp. 499-532) edited by Michael S. Donnenberg. Cambridge, MA, United States: Academic Press. doi: 10.1016/B978-0-12-397048-0.00016-4

Fernandes, Joiselle B., Naish, Matthew, Lian, Qichao, Burns, Robin, Tock, Andrew J., Rabanal, Fernando A., Wlodzimierz, Piotr, Habring, Anette, Nicholas, Robert E., Weigel, Detlef, Mercier, Raphael and Henderson, Ian R. (2024). Structural variation and DNA methylation shape the centromere-proximal meiotic crossover landscape in Arabidopsis. Genome Biology, 25 (1) 30. doi: 10.1186/s13059-024-03163-4

Hickson, Sarah M., Hoehensteiger, Johannes K., Mayer-Coverdale, Johanna, Torres, Von Vergel L., Feng, Wenkang, Monteith, Joshua N., Henderson, Ian R., McCarthy, Kate L. and Wells, Timothy J. (2024). Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections. The Journal of Infectious Diseases. doi: 10.1093/infdis/jiad457

Naish, Matthew and Henderson, Ian R. (2024). The structure, function, and evolution of plant centromeres. Genome Research, 34 (1), 161-178. doi: 10.1101/gr.278409.123

Warner, Isabel A., Kok, Weine J., Martinelli, Nicole, Yang, Zihao, Goodall, Emily C. A. and Henderson, Ian (2023). Microbial primer: transposon directed insertion site sequencing (TraDIS): a high throughput method for linking genotype to phenotype. Microbiology, 169 (11) 001385. doi: 10.1099/mic.0.001385

Pillay, Roxanne, Mkhize-Kwitshana, Zilungile L., Horsnell, William G C, Icke, Christopher, Henderson, Ian, Selkirk, Murray E., Berkachy, Rita, Naidoo, Pragalathan, Niehaus, Abraham J., Singh, Ravesh, Cunningham, Adam F. and O'Shea, Matthew K. (2023). Excretory-secretory products from adult helminth Nippostrongylus brasiliensis have in vitro bactericidal activity. Journal of medical microbiology, 72 (11) 001762. doi: 10.1099/jmm.0.001762

Salim, Angela A., Butler, Mark S., Blaskovich, Mark A. T., Henderson, Ian R. and Capon, Robert J. (2023). Natural products as anthelmintics: safeguarding animal health. Natural Product Reports, 40 (11), 1754-1808. doi: 10.1039/d3np00019b

Wlodzimierz, Piotr, Rabanal, Fernando A., Burns, Robin, Naish, Matthew, Primetis, Elias, Scott, Alison, Mandáková, Terezie, Gorringe, Nicola, Tock, Andrew J., Holland, Daniel, Fritschi, Katrin, Habring, Anette, Lanz, Christa, Patel, Christie, Schlegel, Theresa, Collenberg, Maximilian, Mielke, Miriam, Nordborg, Magnus, Roux, Fabrice, Shirsekar, Gautam, Alonso-Blanco, Carlos, Lysak, Martin A., Novikova, Polina Y., Bousios, Alexandros, Weigel, Detlef and Henderson, Ian R. (2023). Cycles of satellite and transposon evolution in Arabidopsis centromeres. Nature, 618 (7965), 557-565. doi: 10.1038/s41586-023-06062-z

Butler, Mark S., Henderson, Ian R., Capon, Robert J. and Blaskovich, Mark A. T. (2023). Antibiotics in the clinical pipeline as of December 2022. The Journal of Antibiotics, 76 (8), 431-473. doi: 10.1038/s41429-023-00629-8

Wlodzimierz, Piotr, Hong, Michael and Henderson, Ian R. (2023). TRASH: Tandem Repeat Annotation and Structural Hierarchy. Bioinformatics, 39 (5) btad308. doi: 10.1093/bioinformatics/btad308

Goodall, Emily C. A., Azevedo Antunes, Camila, Möller, Jens, Sangal, Vartul, Torres, Von Vergel L., Gray, Jessica, Cunningham, Adam F., Hoskisson, Paul A., Burkovski, Andreas and Henderson, Ian R. (2023). A multiomic approach to defining the essential genome of the globally important pathogen Corynebacterium diphtheriae. PLoS Genetics, 19 (4) e1010737, e1010737. doi: 10.1371/journal.pgen.1010737

Marcial-Juárez, Edith, Pérez-Toledo, Marisol, Nayar, Saba, Pipi, Elena, Alshayea, Areej, Persaud, Ruby, Jossi, Sian E., Lamerton, Rachel, Barone, Francesca, Henderson, Ian R. and Cunningham, Adam F. (2023). Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers. iScience, 26 (4) 106310, 1-22. doi: 10.1016/j.isci.2023.106310

Beriotto, Irene, Icke, Christopher, Sevastsyanovich, Yanina R., Rossiter, Amanda E., Romagnoli, Giacomo, Savino, Silvana, Hodges, Freya J., Cole, Jeffrey A., Saul, Allan, MacLennan, Calman A., Cunningham, Adam F., Micoli, Francesca and Henderson, Ian R. (2023). Efficient autotransporter-mediated extracellular secretion of a heterologous recombinant protein by Escherichia coli. Microbiology Spectrum, 11 (3), e0359422. doi: 10.1128/spectrum.03594-22

Ageorges, Valentin, Wawrzyniak, Ivan, Ruiz, Philippe, Bicep, Cédric, Zorgani, Mohamed A., Paxman, Jason J., Heras, Begoña, Henderson, Ian R., Leroy, Sabine, Bailly, Xavier, Sapountzis, Panagiotis, Peyretaillade, Eric and Desvaux, Mickaël (2023). Genome-wide analysis of Antigen 43 (Ag43) variants: new insights in their diversity, distribution and prevalence in bacteria. International Journal of Molecular Sciences, 24 (6) 5500, 1-24. doi: 10.3390/ijms24065500

Butler, Mark S., Henderson, Ian R., Capon, Robert J. and Blaskovich, Mark A. T. (2023). Correction: Antibiotics in the clinical pipeline as of December 2022 (The Journal of Antibiotics, (2023), 76, 8, (431-473), 10.1038/s41429-023-00629-8). Journal of Antibiotics, 77 (1), 71-71. doi: 10.1038/s41429-023-00671-6

Yu, Zhigang, Henderson, Ian R. and Guo, Jianhua (2023). Non-caloric artificial sweeteners modulate conjugative transfer of multi-drug resistance plasmid in the gut microbiota. Gut Microbes, 15 (1) 2157698, 1-15. doi: 10.1080/19490976.2022.2157698

Qin, Jilong, Hong, Yaoqin, Pullela, Karthik, Morona, Renato, Henderson, Ian R. and Totsika, Makrina (2022). A method for increasing electroporation competence of Gram-negative clinical isolates by polymyxin B nonapeptide. Scientific Reports, 12 (1) 11629, 1-8. doi: 10.1038/s41598-022-15997-8

Yu, Zhigang, Goodall, Emily C. A., Henderson, Ian R. and Guo, Jianhua (2022). Plasmids can shift bacterial morphological response against antibiotic stress. Advanced Science, 10 (2) 2203260, 1-12. doi: 10.1002/advs.202203260

Roth, Myriam, Goodall, Emily C. A., Pullela, Karthik, Jaquet, Vincent, François, Patrice, Henderson, Ian R. and Krause, Karl-Heinz (2022). Transposon-directed insertion-site sequencing reveals glycolysis gene gpmA as part of the H2O2 defense mechanisms in Escherichia coli. Antioxidants, 11 (10) 2053, 1-19. doi: 10.3390/antiox11102053

Goodall, Emily C. A., Morris, Faye C., McKeand, Samantha A., Sullivan, Rudi, Warner, Isabel A., Sheehan, Emma, Boelter, Gabriela, Icke, Christopher, Cunningham, Adam F., Cole, Jeffrey A., Banzhaf, Manuel, Bryant, Jack A. and Henderson, Ian R. (2022). LI-detector: a method for curating ordered gene-replacement libraries. Microbiology Spectrum, 10 (4) e0083322, 1-12. doi: 10.1128/spectrum.00833-22

Lamerton, Rachel E., Marcial-Juarez, Edith, Faustini, Sian E., Perez-Toledo, Marisol, Goodall, Margaret, Jossi, Siân E., Newby, Maddy L., Chapple, Iain, Dietrich, Thomas, Veenith, Tonny, Shields, Adrian M., Harper, Lorraine, Henderson, Ian R., Rayes, Julie, Wraith, David C., Watson, Steve P., Crispin, Max, Drayson, Mark T., Richter, Alex G. and Cunningham, Adam F. (2022). SARS-CoV-2 spike- and nucleoprotein-specific antibodies induced after vaccination or infection promote classical complement activation. Frontiers in Immunology, 13 838780, 1-13. doi: 10.3389/fimmu.2022.838780

Boelter, Gabriela, Bryant, Jack A., Doherty, Hannah, Wotherspoon, Peter, Alodaini, Dema, Ma, Xuyu, Alao, Micheal B., Moynihan, Patrick J., Moradigaravand, Danesh, Glinkowska, Monika, Knowles, Timothy J., Henderson, Ian R. and Banzhaf, Manuel (2022). The lipoprotein DolP affects cell separation in Escherichia coli, but not as an upstream regulator of NlpD. Microbiology, 168 (5) 001197, 1-10. doi: 10.1099/mic.0.001197

Freire, Claudia A., Silva, Rosa M., Ruiz, Rita C., Pimenta, Daniel C., Bryant, Jack A., Henderson, Ian R., Barbosa, Angela S. and Elias, Waldir P. (2022). Secreted autotransporter toxin (Sat) mediates innate immune system evasion. Frontiers in Immunology, 13 844878, 844878. doi: 10.3389/fimmu.2022.844878

Goodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2021). Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS Genetics, 17 (12) e1009586, 1-40. doi: 10.1371/journal.pgen.1009586

Yu, Zhigang, Wang, Yue, Henderson, Ian R. and Guo, Jianhua (2021). Artificial sweeteners stimulate horizontal transfer of extracellular antibiotic resistance genes through natural transformation. The ISME Journal, 16 (2), 1-12. doi: 10.1038/s41396-021-01095-6

Pham, Amy, Ledger, Emma L., Coggon, Carrie F., Henderson, Ian R., Reid, David W., Bell, Scott C., Smith, Daniel J. and Wells, Timothy J. (2021). Anti-LPS IgA and IgG can inhibit serum killing of Pseudomonas aeruginosa in patients with cystic fibrosis. Infection and Immunity, 89 (12) e00412-21, e0041221. doi: 10.1128/iai.00412-21

Winkle, Matthias, Hernández-Rocamora, Víctor M., Pullela, Karthik, Goodall, Emily C. A., Martorana, Alessandra M., Gray, Joe, Henderson, Ian R., Polissi, Alessandra and Vollmer, Waldemar (2021). DpaA detaches Braun’s lipoprotein from peptidoglycan. mBio, 12 (3) e00836-21. doi: 10.1128/mbio.00836-21

Icke, Christopher, Hodges, Freya J., Pullela, Karthik, McKeand, Samantha A., Bryant, Jack Alfred, Cunningham, Adam F., Cole, Jeff A. and Henderson, Ian R. (2021). Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system. eLife, 10 e63762, 1-24. doi: 10.7554/elife.63762

Rooke, Jessica L., Icke, Christopher, Wells, Timothy J, Rossiter, Amanda E., Browning, Douglas F., Morris, Faye C., Leo, Jack C., Schütz, Monika S., Autenrieth, Ingo B., Cunningham, Adam F., Linke, Dirk and Henderson, Ian R. (2021). BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Frontiers in Microbiology, 12 628879, 1-10. doi: 10.3389/fmicb.2021.628879

Bryant, Jack A., Cadby, Ian T., Chong, Zhi-Soon, Boelter, Gabriela, Sevastsyanovich, Yanina R., Morris, Faye C., Cunningham, Adam F., Kritikos, George, Meek, Richard W., Banzhaf, Manuel, Chng, Shu-Sin, Lovering, Andrew L. and Henderson, Ian R. (2021). Structure-function characterization of the conserved regulatory mechanism of the Escherichia coli M48-metalloprotease BepA. Journal of Bacteriology, 203 (2) e00434-20, e00434-20. doi: 10.1128/jb.00434-20

Henderson, Ian R. and Bomblies, Kirsten (2021). Evolution and plasticity of genome-wide meiotic recombination rates. Annual Review of Genetics, 55 (1), 23-43. doi: 10.1146/annurev-genet-021721-033821

Perez-Toledo, Marisol, Beristain-Covarrubias, Nonantzin, Channell, William M., Hitchcock, Jessica R., Cook, Charlotte N., Coughlan, Ruth E., Bobat, Saeeda, Jones, Nicholas D., Nakamura, Kyoko, Ross, Ewan A., Rossiter, Amanda E., Rooke, Jessica, Garcia-Gimenez, Alicia, Jossi, Sian, Persaud, Ruby R., Marcial-Juarez, Edith, Flores-Langarica, Adriana, Henderson, Ian R., Withers, David R., Watson, Steve P. and Cunningham, Adam F. (2020). Mice deficient in T-bet form inducible NO synthase-positive granulomas that fail to constrain Salmonella. Journal of Immunology, 205 (3), 708-719. doi: 10.4049/jimmunol.2000089

Cranford-Smith, Tamar, Jamshad, Mohammed, Jeeves, Mark, Chandler, Rachael A., Yule, Jack, Robinson, Ashley, Alam, Farhana, Dunne, Karl A., Aponte Angarita, Edwin H., Alanazi, Mashael, Carter, Cailean, Henderson, Ian R., Lovett, Janet E., Winn, Peter, Knowles, Timothy and Huber, Damon (2020). Iron is a ligand of SecA-like metal-binding domains in vivo. Journal of Biological Chemistry, 295 (21), jbc.RA120.012611-7528. doi: 10.1074/jbc.ra120.012611

Domínguez-Medina, C. Coral, Pérez-Toledo, Marisol, Schager, Anna E., Marshall, Jennifer L., Cook, Charlotte N., Bobat, Saeeda, Hwang, Hyea, Chun, Byeong Jae, Logan, Erin, Bryant, Jack A., Channell, Will M., Morris, Faye C., Jossi, Sian E., Alshayea, Areej, Rossiter, Amanda E., Barrow, Paul A., Horsnell, William G., MacLennan, Calman A., Henderson, Ian R., Lakey, Jeremy H., Gumbart, James C., López-Macías, Constantino, Bavro, Vassiliy N. and Cunningham, Adam F. (2020). Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface. Nature Communications, 11 (1) 851, 851. doi: 10.1038/s41467-020-14655-9

Beristain-Covarrubias, Nonantzin, Perez-Toledo, Marisol, Thomas, Mark R., Henderson, Ian R., Watson, Steve P. and Cunningham, Adam F. (2019). Understanding infection-induced thrombosis: lessons learned from animal models. Frontiers in Immunology, 10 2569, 2569. doi: 10.3389/fimmu.2019.02569

Hughes, Gareth W., Hall, Stephen C. L., Laxton, Claire S., Sridhar, Pooja, Mahadi, Amirul H., Hatton, Caitlin, Piggot, Thomas J., Wotherspoon, Peter J., Leney, Aneika C., Ward, Douglas G., Jamshad, Mohammed, Spana, Vaclav, Cadby, Ian T., Harding, Christopher, Isom, Georgia L., Bryant, Jack A., Parr, Rebecca J., Yakub, Yasin, Jeeves, Mark, Huber, Damon, Henderson, Ian R., Clifton, Luke A., Lovering, Andrew L. and Knowles, Timothy J. (2019). Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system. Nature Microbiology, 4 (10), 1692-1705. doi: 10.1038/s41564-019-0481-y

Dawson, Emma M., Dunne, Karl A., Richardson, Emily J., Praszkier, Judyta, Alfawaz, Dana, Woelfel, Simon, De Paoli, Amanda, Chaudhry, Hassan, Henderson, Ian R., Ferrero, Richard L. and Rossiter, Amanda E. (2019). Complete genome sequence of Helicobacter pylori B128 7.13 and a single-step method for the generation of unmarked mutations. Helicobacter, 24 (4) e12587, e12587. doi: 10.1111/hel.12587

Ageorges, Valentin, Schiavone, Marion, Jubelin, Gregory, Caccia, Nelly, Ruiz, Philippe, Chafsey, Ingrid, Bailly, Xavier, Dague, Etienne, Leroy, Sabine, Paxman, Jason, Heras, Begona, Chaucheyras-Durand, Frederique, Rossiter, Amanda E., Henderson, Ian R. and Desvaux, Mickael (2019). Differential homotypic and heterotypic interactions of antigen 43 (Ag43) variants in autotransporter-mediated bacterial autoaggregation. Scientific Reports, 9 (1) 11100, 11100. doi: 10.1038/s41598-019-47608-4

Santos, Fernanda F., Yamamoto, Denise, Abe, Cecilia M., Bryant, Jack A., Hernandes, Rodrigo T., Kitamura, Felipe C., Castro, Felipe S., Valiatti, Tiago B., Piazza, Roxane M. F., Elias, Waldir P., Henderson, Ian R. and Gomes, Tania A. T. (2019). The Type III Secretion System (T3SS)-Translocon of Atypical Enteropathogenic Escherichia coli (aEPEC) Can Mediate Adherence. Frontiers in Microbiology, 10 (July) 1527. doi: 10.3389/fmicb.2019.01527

Yasir, Muhammad, Icke, Christopher, Abdelwahab, Radwa, Haycocks, James R, Godfrey, Rita E, Sazinas, Pavelas, Pallen, Mark J, Henderson, Ian R, Busby, Stephen J W and Browning, Douglas F (2019). Organization and architecture of AggR-dependent promoters from Enteroaggregative Escherichia coli. Molecular microbiology, 111 (2), 534-551. doi: 10.1111/mmi.14172

Bravo-Blas, Alberto, Utriainen, Lotta, Clay, Slater L., Kästele, Verena, Cerovic, Vuk, Cunningham, Adam F., Henderson, Ian R., Wall, Daniel M. and Milling, Simon W. F. (2019). Salmonella enterica serovar typhimurium travels to mesenteric lymph nodes both with host cells and autonomously. Journal of Immunology, 202 (1), 260-267. doi: 10.4049/jimmunol.1701254

Santos, Fernanda F., Richardson, Emily J., Bryant, Jack A., Yamamoto, Denise, Elias, Waldir P., Gomes, Tânia A.T. and Henderson, Ian R. (2018). Draft whole-genome sequences of 10 atypical enteropathogenic Escherichia coli strains isolated in Brazil. Microbiology Resource Announcements, 7 (22) e01432-18. doi: 10.1128/MRA.01432-18

Beristain-Covarrubias, Nonantzin, Perez-Toledo, Marisol, Flores-Langarica, Adriana, Zuidscherwoude, Malou, Hitchcock, Jessica R., Channell, Will M., King, Lloyd D. W., Thomas, Mark R., Henderson, Ian R., Rayes, Julie, Watson, Steve P. and Cunningham, Adam F. (2018). Salmonella-induced thrombi in mice develop asynchronously in the spleen and liver and are not effective bacterial traps. Blood, 133 (6), 600-604. doi: 10.1182/blood-2018-08-867267

Morris, Faye C., Wells, Timothy J., Bryant, Jack A., Schager, Anna E., Sevastsyanovich, Yanina R., Squire, Derrick J. P., Marshall, Jennifer, Isom, Georgia L., Rooke, Jessica, Maderbocus, Riyaz, Knowles, Timothy J., Overduin, Michael, Rossiter, Amanda E., Cunningham, Adam F. and Henderson, Ian R. (2018). YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium. Infection and Immunity, 86 (11) e00829-17. doi: 10.1128/IAI.00829-17

Flores-Langarica, Adriana, Cook, Charlotte, Müller Luda, Katarzyna, Persson, Emma K., Marshall, Jennifer L., Beristain-Covarrubias, Nonantzin, Yam-Puc, Juan Carlos, Dahlgren, Madelene, Persson, Jenny J., Uematsu, Satoshi, Akira, Shizuo, Henderson, Ian R., Lindbom, Bengt Johansson, Agace, William and Cunningham, Adam F. (2018). Intestinal CD103+CD11b+ cDC2 conventional dendritic cells are required for primary CD4+ T and B cell responses to soluble flagellin. Frontiers in Immunology, 9 (OCT) 2409. doi: 10.3389/fimmu.2018.02409

Grinter, Rhys, Hay, Iain D., Song, Jiangning, Wang, Jiawei, Teng, Don, Dhanesakaran, Vijay, Wilksch, Jonathan J., Davies, Mark R., Littler, Dene, Beckham, Simone A., Henderson, Ian R., Strugnell, Richard A., Dougan, Gordon and Lithgow, Trevor (2018). FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants. PLoS biology, 16 (8) e2006026, e2006026. doi: 10.1371/journal.pbio.2006026

Coggon, Carrie F., Jiang, Andrew, Goh, Kelvin G. K., Henderson, Ian R., Schembri, Mark A. and Wells, Timothy J. (2018). A novel method of serum resistance by Escherichia coli that causes urosepsis. mBio, 9 (3) e00920-18, e00920-18. doi: 10.1128/mbio.00920-18

Flores-Langarica, A., Müller Luda, K., Persson, E. K., Cook, C. N., Bobat, S., Marshall, J. L., Dahlgren, M. W., Hägerbrand, K., Toellner, K. M., Goodall, M. D., Withers, D. R., Henderson, I. R., Johansson Lindbom, B., Cunningham, A. F. and Agace, W. W. (2018). CD103 + CD11b + mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin. Mucosal Immunology, 11 (3), 681-692. doi: 10.1038/mi.2017.105

Yuan, Xiaojun, Johnson, Matthew D., Zhang, Jing, Lo, Alvin W., Schembri, Mark A., Wijeyewickrema, Lakshmi C., Pike, Robert N., Huysmans, Gerard H. M., Henderson, Ian R. and Leyton, Denisse L. (2018). Molecular basis for the folding of β-helical autotransporter passenger domains. Nature Communications, 9 (1) 1395, 1395. doi: 10.1038/s41467-018-03593-2

Wall, Nadezhda A., Coral Dominguez-Medina, C., Faustini, Sian E., Cook, Charlotte N., McClean, Andrew, Jesky, Mark D., Perez-Toledo, Marisol, Morgan, Matthew D., Richter, Alexandra G., Ferro, Charles J., Cockwell, Paul, Moss, Paul A., Henderson, Ian R., Harper, Lorraine and Cunningham, Adam F. (2018). Humoral immunity to memory antigens and pathogens is maintained in patients with chronic kidney disease. PLoS ONE, 13 (4) e0195730, e0195730. doi: 10.1371/journal.pone.0195730

Hammarlof, Disa L., Kroger, Carsten, Owen, Sian V., Canals, Rocio, Lacharme-Lora, Lizeth, Wenner, Nicolas, Schager, Anna E., Wells, Timothy J., Henderson, Ian R., Wigley, Paul, Hokamp, Karsten, Feasey, Nicholas A., Gordon, Melita A. and Hinton, Jay C. D. (2018). Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. Proceedings of the National Academy of Sciences of the United States of America, 115 (11), E2614-E2623. doi: 10.1073/pnas.1714718115

Goodall, Emily C. A., Robinson, Ashley, Johnston, Iain G., Jabbari, Sara, Turner, Keith A., Cunningham, Adam F., Lund, Peter A., Cole, Jeffrey A. and Henderson, Ian R. (2018). The essential genome of Escherichia coli K-12. mBio, 9 (1) e02096-17. doi: 10.1128/mBio.02096-17

Antunes, Camila Azevedo, Richardson, Emily J., Quick, Joshua, Fuentes-Utrilla, Pablo, Isom, Georgia L., Goodall, Emily C., Möller, Jens, Hoskisson, Paul A., Mattos-Guaraldi, Ana Luiza, Cunningham, Adam F., Loman, Nicholas J., Sangal, Vartul, Burkovski, Andreas and Henderson, Ian R. (2018). Complete closed genome sequence of nontoxigenic invasive Corynebacterium diphtheriae bv. mitis strain ISS 3319. Genome Announcements, 6 (5) e01566-17. doi: 10.1128/genomeA.01566-17

Rojas-Lopez, Maricarmen, Zorgani, Mohamed A., Kelley, Lawrence A., Bailly, Xavier, Kajava, Andrey V., Henderson, Ian R., Polticelli, Fabio, Pizza, Mariagrazia, Rosini, Roberto and Desvaux, Mickaël (2018). Identification of the autochaperone domain in the type va secretion system (T5aSS): prevalent feature of autotransporters with a β-helical passenger. Frontiers in Microbiology, 8 (JAN) 2607. doi: 10.3389/fmicb.2017.02607

Isom, Georgia L., Davies, Nathaniel J., Chong, Zhi-Soon, Bryant, Jack A., Jamshad, Mohammed, Sharif, Maria, Cunningham, Adam F., Knowles, Timothy J., Chng, Shu-Sin, Cole, Jeffrey A. and Henderson, Ian R. (2017). MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis. Scientific Reports, 7 (1) 8608. doi: 10.1038/s41598-017-09111-6

Sevastsyanovich, Yanina R., Withers, David R., Marriott, Claire L., Morris, Faye C., Wells, Timothy J., Browning, Douglas F., Beriotto, Irene, Ross, Ewan, Ali, Hossam Omar, Wardius, Catherine A., Cunningham, Adam F., Henderson, Ian R. and Rossiter, Amanda E. (2017). Antigen localization influences the magnitude and kinetics of endogenous adaptive immune response to recombinant Salmonella vaccines. Infection and Immunity, 85 (12) e00593-17, e00593-17. doi: 10.1128/iai.00593-17

Marini, Arianna, Rossi, Omar, Aruta, Maria Grazia, Micoli, Francesca, Rondini, Simona, Guadagnuolo, Serafina, Delany, Isabel, Henderson, Ian R., Cunningham, Adam F., Saul, Allan, MacLennan, Calman A. and Koeberling, Oliver (2017). Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1. PLoS One, 12 (7) e0181508, e0181508. doi: 10.1371/journal.pone.0181508

Ekiert, Damian C., Bhabha, Gira, Isom, Georgia L., Greenan, Garrett, Ovchinnikov, Sergey, Henderson, Ian R., Cox, Jeffery S. and Vale, Ronald D. (2017). Architectures of lipid transport systems for the bacterial outer membrane. Cell, 169 (2), 273-285.e17. doi: 10.1016/j.cell.2017.03.019

Wells, Timothy J., Davison, John, Sheehan, Emma, Kanagasundaram, Suren, Spickett, Gavin, MacLennan, Calman A., Stockley, Robert A., Cunningham, Adam F., Henderson, Ian R. and De Soyza, Anthony (2017). The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies. American Journal of Respiratory and Critical Care Medicine, 195 (7), 955-958. doi: 10.1164/rccm.201603-0599LE

Dunne, Karl A., Chaudhuri, Roy R., Rossiter, Amanda E., Beriotto, Irene, Browning, Douglas F., Squire, Derrick, Cunningham, Adam F., Cole, Jeffrey A., Loman, Nicholas and Henderson, Ian R. (2017). Sequencing a piece of history: complete genome sequence of the original Escherichia coli strain. Microbial Genomics, 3 (3) 000106. doi: 10.1099/mgen.0.000106

Watson, Callum N., Kerrigan, Steven W., Cox, Dermot, Henderson, Ian R., Watson, Steve P. and Arman, Mònica (2016). Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3. Platelets, 27 (6), 535-540. doi: 10.3109/09537104.2016.1148129

Monteiro, Ricardo, Ageorges, Valentin, Rojas-Lopez, Maricarmen, Schmidt, Herbert, Weiss, Agnes, Bertin, Yolande, Forano, Evelyne, Jubelin, Grégory, Henderson, Ian R., Livrelli, Valérie, Gobert, Alain P., Rosini, Roberto, Soriani, Marco and Desvaux, Mickaël (2016). A secretome view of colonisation factors in Shiga toxin-encoding Escherichia coli (STEC): from enterohaemorrhagic E. coli (EHEC) to related enteropathotypes. FEMS Microbiology Letters, 363 (16) fnw179, fnw179. doi: 10.1093/femsle/fnw179

Nichols, Katie B., Totsika, Makrina, Moriel, Danilo G., Lo, Alvin W., Yang, Ji, Wurpel, Daniel J., Rossiter, Amanda E., Strugnell, Richard A., Henderson, Ian R., Ulett, Glen C., Beatson, Scott A. and Schembri, Mark A. (2016). Molecular characterisation of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli. Journal of Bacteriology, 198 (10), 1487-1498. doi: 10.1128/JB.00791-15

Czaplewski, Lloyd, Bax, Richard, Clokie, Martha, Dawson, Mike, Fairhead, Heather, Fischetti, Vincent A., Foster, Simon, Gilmore, Brendan F., Hancock, Robert E. W., Harper, David, Henderson, Ian R., Hilpert, Kai, Jones, Brian V., Kadioglu, Aras, Knowles, David, Ólafsdóttir, Sigrídur, Payne, David, Projan, Steve, Shaunak, Sunil, Silverman, Jared, Thomas, Christopher M., Trust, Trevor J., Warn, Peter and Rex, John H. (2016). Alternatives to antibiotics-a pipeline portfolio review. The Lancet Infectious Diseases, 16 (2), 239-251. doi: 10.1016/S1473-3099(15)00466-1

Hitchcock, Jessica R., Cook, Charlotte N., Bobat, Saeeda, Ross, Ewan A., Flores-Langarica, Adriana, Lowe, Kate L., Khan, Mahmood, Dominguez-Medina, C. Coral, Lax, Sian, Carvalho-Gaspar, Manuela, Hubscher, Stefan, Rainger, G. Ed, Cobbold, Mark, Buckley, Christopher D., Mitchell, Tim J., Mitchell, Andrea, Jones, Nick D., Van Rooijen, N., Kirchhofer, Daniel, Henderson, Ian R., Adams, David H., Watson, Steve P. and Cunningham, Adam F. (2015). Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets. Journal of Clinical Investigation, 125 (12), 4429-4446. doi: 10.1172/jci79070

Flores-Langarica, Adriana, Bobat, Saeeda, Marshall, Jennifer L., Yam-Puc, Juan Carlos, Cook, Charlotte N., Serre, Karine, Kingsley, Robert A., Flores-Romo, Leopoldo, Uematsu, Satoshi, Akira, Shizuo, Henderson, Ian R., Toellner, Kai M. and Cunningham, Adam F. (2015). Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production: immunity to infection. European Journal of Immunology, 45 (8), 2299-2311. doi: 10.1002/eji.201545564

Browning, Douglas F., Bavro, Vassiliy N., Mason, Jessica L., Sevastsyanovich, Yanina R., Rossiter, Amanda E., Jeeves, Mark, Wells, Timothy J., Knowles, Timothy J., Cunningham, Adam F., Donald, James W., Palmer, Tracy, Overduin, Michael and Henderson, Ian R. (2015). Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion. Molecular Microbiology, 97 (4), 646-659. doi: 10.1111/mmi.13052

Rossiter, Amanda E., Godfrey, Rita E., Connolly, Jack A., Busby, Stephen J. W., Henderson, Ian R. and Browning, Douglas F. (2015). Expression of different bacterial cytotoxins is controlled by two global transcription factors, CRP and Fis, that co-operate in a shared-recruitment mechanism. Biochemical Journal, 466 (2), 323-335. doi: 10.1042/BJ20141315

Bobat, Saeeda, Darby, Matthew, Mrdjen, Dunja, Cook, Charlotte, Logan, Erin, Auret, Jennifer, Jones, Elizabeth, Schnoeller, Corinna, Flores-Langarica, Adriana, Ross, Ewan A., Vira, Alykhan, López-Macías, Constantino, Henderson, Ian R., Alexander, James, Brombacher, Frank, Horsnell, William G. and Cunningham, Adam F. (2014). Natural and vaccine-mediated immunity to Salmonella typhimurium is impaired by the helminth Nippostrongylus brasiliensis. PLoS Neglected Tropical Diseases, 8 (12) e3341, e3341. doi: 10.1371/journal.pntd.0003341

Cunningham, Adam E., Flores-Langarica, Adriana, Bobat, Saeeda, Medina, Carmen C. Dominguez, Cook, Charlotte N. L., Ross, Ewan A., Lopez-Macias, Constantino and Henderson, Ian R. (2014). B1b cells recognize protective antigens after natural infection and vaccination. Frontiers in Immunology, 5 (OCT) 535. doi: 10.3389/fimmu.2014.00535

Wells, Timothy J., Whitters, Deborah, Sevastsyanovich, Yanina R., Heath, Jennifer N., Pravin, John, Goodall, Margaret, Browning, Douglas F., O'Shea, Matthew K., Cranston, Amy, De Soyza, Anthony, Cunningham, Adam F., MacLennan, Calman A., Henderson, Ian R. and Stockley, Robert A. (2014). Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing. Journal of Experimental Medicine, 211 (9), 1893-1904. doi: 10.1084/jem.20132444

Leyton, Denisse L., Johnson, Matthew D., Thapa, Rajiv, Huysmans, Gerard H. M., Dunstan, Rhys A., Celik, Nermin, Shen, Hsin-Hui, Loo, Dorothy, Belousoff, Matthew J., Purcell, Anthony W., Henderson, Ian R., Beddoe, Travis, Rossjohn, Jamie, Martin, Lisandra L., Strugnell, Richard A. and Lithgow, Trevor (2014). A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes. Nature Communications, 5 (1) 4239. doi: 10.1038/ncomms5239

Ross, Ewan A., Flores-Langarica, Adriana, Bobat, Saeeda, Coughlan, Ruth E., Marshall, Jennifer L., Hitchcock, Jessica R., Cook, Charlotte N., Carvalho-Gaspar, Manuela M., Mitchell, Andrea M., Clarke, Mary, Garcia, Paloma, Cobbold, Mark, Mitchell, Tim J., Henderson, Ian R., Jones, Nick D., Anderson, Graham, Buckley, Christopher D. and Cunningham, Adam F. (2014). Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function: cellular immune response. European Journal of Immunology, 44 (8), 2318-2330. doi: 10.1002/eji.201344350

Siggins, Matthew K., O'Shaughnessy, Colette M., Pravin, John, Cunningham, Adam F., Henderson, Ian R., Drayson, Mark T. and MacLennan, Calman A. (2014). Differential timing of antibody-mediated phagocytosis and cell-free killing of invasive African Salmonella allows immune evasion. European Journal of Immunology, 44 (4), 1093-1098. doi: 10.1002/eji.201343529

Browning, Douglas F., Matthews, Sophie A., Rossiter, Amanda E., Sevastsyanovich, Yanina R., Jeeves, Mark, Mason, Jessica L., Wells, Timothy J., Wardius, Catherine A., Knowles, Timothy J., Cunningham, Adam F., Bavro, Vassiliy N., Overduin, Michael and Henderson, Ian R. (2013). Mutational and topological analysis of the Escherichia coli BamA protein. PLoS ONE, 8 (12) e84512, e84512. doi: 10.1371/journal.pone.0084512

Franca, Fernanda L. S., Wells, Timothy J., Browning, Douglas F., Nogueira, Raquel Tayar, Sarges, Felipe Silva, Pereira, Ana Claudia, Cunningham, Adam F., Lucheze, Kely, Paula Rosa, Ana Claudia, Henderson, Ian R. and de Luna, Maria das Gracas (2013). Genotypic and phenotypic characterisation of enteroaggregative Escherichia coli from children in Rio de Janeiro, Brazil. PLoS ONE, 8 (7) e69971, e69971. doi: 10.1371/journal.pone.0069971

Browning, Douglas F., Wells, Timothy J., Franca, Fernanda L. S., Morris, Faye C., Sevastsyanovich, Yanina R., Bryant, Jack A., Johnson, Matthew D., Lund, Peter A., Cunningham, Adam F., Hobman, Jon L., May, Robin C., Webber, Mark A. and Henderson, Ian R. (2013). Laboratory adapted Escherichia coli K-12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis. Molecular Microbiology, 87 (5), 939-950. doi: 10.1111/mmi.12144

Marshall, Jennifer L. , Flores-Langarica, Adriana, Kingsley, Robert A. , Hitchcock, Jessica R., Ross, Ewan A., Lopez-Macias, Constantino, Lakey, Jeremy, Martin, Laura B., Toellner, Kai-Michael, MacLennan, Calman A., MacLennan, Ian C., Henderson, Ian R., Dougan, Gordon and Cunningham, Adam F. (2012). The capsular polysaccharide Vi from Salmonella typhi is a B1b antigen. The Journal of Immunology, 189 (12), 5527-5532. doi: 10.4049/jimmunol.1103166

Flores-Langarica, Adriana, Marshall, Jennifer L., Hitchcock, Jessica, Cook, Charlotte, Jobanputra, Jonathan, Bobat, Saeeda, Ross, Ewan A., Coughlan, Ruth E., Henderson, Ian R., Uematsu, Satoshi, Akira, Shizuo and Cunningham, Adam F. (2012). Systemic flagellin immunization stimulates mucosal CD103+ dendritic cells and drives Foxp3+ regulatory T cell and IgA responses in the mesenteric lymph node. The Journal of Immunology, 189 (12), 5745-5754. doi: 10.4049/jimmunol.1202283

Ross, Ewan A., Coughlan, Ruth E., Flores-Langarica, Adriana, Lax, Sian, Nicholson, Julia, Desanti, Guillaume E., Marshall, Jennifer L., Bobat, Saeeda, Hitchcock, Jessica, White, Andrea, Jenkinson, William E., Khan, Mahmood, Henderson, Ian R., Lavery, Gareth G., Buckley, Christopher D., Anderson, Graham and Cunningham, Adam F. (2012). Thymic function is maintained during Salmonella -induced atrophy and recovery. The Journal of Immunology, 189 (9), 4266-4274. doi: 10.4049/jimmunol.1200070

Pallen, Mark and Henderson, Ian (2012). Pride in a century-long tradition of microbiology in Birmingham. Microbiology Today, 39 (3), 156-159.

Sevastsyanovich, Yanina R., Leyton, Denisse L., Wells, Timothy J., Wardius, Catherine A., Tveen-Jensen, Karina, Morris, Faye C., Knowles, Timothy J., Cunningham, Adam F., Cole, Jeffrey A. and Henderson, Ian R. (2012). A generalised module for the selective extracellular accumulation of recombinant proteins. Microbial Cell Factories, 11 (69) 69. doi: 10.1186/1475-2859-11-69

Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 (5), 506-510. doi: 10.1038/nsmb.2261

Chaudhuri, Roy R. and Henderson, Ian R. (2012). The evolution of the Escherichia coli phylogeny. Infection, Genetics and Evolution, 12 (2), 214-226. doi: 10.1016/j.meegid.2012.01.005

Leyton, Denisse L., Rossiter, Amanda E. and Henderson, Ian R. (2012). From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis. Nature Reviews Microbiology, 10 (3), 213-225. doi: 10.1038/nrmicro2733

Leyton, Denisse L., Sevastsyanovich, Yanina R., Browning, Douglas F., Rossiter, Amanda E., Wells, Timothy J., Fitzpatrick, Rebecca E., Overduin, Michael, Cunningham, Adam F. and Henderson, Ian R. (2011). Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins. Journal of Biological Chemistry, 286 (49), 42283-42291. doi: 10.1074/jbc.M111.306118

Stincone, Anna, Daudi, Nazish, Rahman, Ayesha S., Antczak, Philipp, Henderson, Ian, Cole, Jeffrey, Johnson, Matthew D., Lund, Peter and Falciani, Francesco (2011). A systems biology approach sheds new light on Escherichia coli acid resistance. Nucleic Acids Research, 39 (17), 7512-7528. doi: 10.1093/nar/gkr338

Flores-Langarica, Adriana, Marshall, Jennifer L., Bobat, Saeeda, Mohr, Elodie, Hitchcock, Jessica, Ross, Ewan A., Coughlan, Ruth E., Khan, Mahmood, Van Rooijen, Nico, Henderson, Ian R., Maclennan, Ian C. M. and Cunningham, Adam F. (2011). T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella. European journal of immunology, 41 (9), 2654-65. doi: 10.1002/eji.201141440

Ross, Ewan A., Coughlan, Ruth E., Flores-Langarica, Adriana, Bobat, Saeeda, Marshall, Jennifer L., Hussain, Khiyam, Charlesworth, James, Abhyankar, Nikita, Hitchcock, Jessica, Gil, Cristina, Loṕez-Maciás, Constantino, Henderson, Ian R., Khan, Mahmood, Watson, Steve P., MacLennan, Ian C. M., Buckley, Christopher D. and Cunningham, Adam F. (2011). Cd31 is required on cd4+ T cells to promote T cell survival during Salmonella infection. Journal of Immunology, 187 (4), 1553-1565. doi: 10.4049/jimmunol.1000502

Rossiter, Amanda E., Leyton, Denisse L., Tveen-Jensen, Karina, Browning, Douglas F., Sevastsyanovich, Yanina, Knowles, Timothy J., Nichols, Katie B., Cunningham, Adam F., Overduin, Michael, Schembri, Mark A. and Henderson, Ian R. (2011). The essential beta-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis. Journal of Bacteriology, 193 (16), 4250-4253. doi: 10.1128/JB.00192-11

Rossiter, Amanda E., Browning, Douglas F., Leyton, Denisse L., Johnson, Matthew D., Godfrey, Rita E., Wardius, Catherine A., Desvaux, Mickael, Cunningham, Adam F., Ruiz-Perez, Fernando, Nataro, James P., Busby, Stephen J. W. and Henderson, Ian R. (2011). Transcription of the plasmid-encoded toxin gene from Enteroaggregative Escherichia coli is regulated by a novel co-activation mechanism involving CRP and Fis. Molecular Microbiology, 81 (1), 179-191. doi: 10.1111/j.1365-2958.2011.07685.x

Clarke, David J., Chaudhuri, Roy R., Martin, Helen M., Campbell, Barry J., Rhodes, Jonathan M., Constantinidou, Chrystala , Pallen, Mark J., Loman, Nicholas J., Cunningham, Adam F., Browning, Douglas F. and Henderson, Ian R. (2011). Complete Genome Sequence of the Crohn's Disease-Associated Adherent-Invasive Escherichia coliStrain HM605. Journal of Bacteriology, 193 (17), 4540-4540. doi: 10.1128/jb.05374-11

Bobat, Saeeda, Flores-Langarica, Adriana, Hitchcock, Jessica, Marshall, Jennifer L., Kingsley, Robert A., Goodall, Margaret, Gil-Cruz, Cristina, Serre, Karine, Leyton, Denisse L., Letran, Shirdi E., Gaspal, Fabrina, Chester, Rebecca, Chamberlain, Jayne L., Dougan, Gordon, López-Macías, Constantino, Henderson, Ian R., Alexander, James, Maclennan, Ian C. M. and Cunningham, Adam F. (2011). Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection. European Journal of Immunology, 41 (6), 1606-1618. doi: 10.1002/eji.201041089

Beatson, Scott A., de Luna, Maria das Graças, Bachmann, Nathan L., Alikhan, Nabil-Fareed, Hanks, Kirstin R., Sullivan, Mitchell J., Wee, Bryan A., Freitas-Almeida, Angela C., dos Santos, Paula A., de Melo, Janyne T. B., Squire, Derrick J. P., Cunningham, Adam F., Fitzgerald, J. Ross and Henderson, Ian R. (2011). Genome sequence of the emerging pathogen aeromonas caviae. Journal of Bacteriology, 193 (5), 1286-1287. doi: 10.1128/JB.01337-10

Siggins, Matthew K., Cunningham, Adam F., Marshall, Jennifer L., Chamberlain, Jayne L., Henderson, Ian R. and MacLennan, Calman A. (2011). Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody. The Journal of Immunology, 186 (4), 2365-71. doi: 10.4049/jimmunol.1000284

Knowles, Timothy J., Browning, Douglas F., Jeeves, Mark, Maderbocus, Riyaz, Rajesh, Sandya, Sridhar, Pooja, Manoli, Eleni, Emery, Danielle, Sommer, Ulf, Spencer, Ashley, Leyton, Denisse L., Squire, Derrick, Chaudhuri, Roy R., Viant, Mark R., Cunningham, Adam F., Henderson, Ian R. and Overduin, Michael (2011). Structure and function of BamE within the outer membrane and the β-barrel assembly machine. EMBO Reports, 12 (2), 123-128. doi: 10.1038/embor.2010.202

Tsai, Jennifer C., Yen, Ming-Ren, Castillo, Rostislav, Leyton, Denisse L., Henderson, Ian R. and Saier, Milton H. (2010). The bacterial intimins and invasins: A large and novel family of secreted proteins. PLoS ONE, 5 (12) e14403, e14403. doi: 10.1371/journal.pone.0014403

Crossman, L. C., Chaudhuri, R. R., Beatson, S. A., Wells, T. J., Desvaux, M., Cunningham, A. F., Petty, N. K., Mahon, V., Brinkley, C., Hobman, J. L., Savarino, S. J., Turner, S. M., Pallen, M. J., Penn, C. W., Parkhill, J., Turner, A. K., Johnson, T. J., Thomson, N. R., Smith, S. G. J. and Henderson, I. R. (2010). A commensal gone bad: Complete genome sequence of the prototypical enterotoxigenic escherichia coli strain H10407. Journal of Bacteriology, 192 (21), 5822-5831. doi: 10.1128/JB.00710-10

Leyton, Denisse L., De Luna, Maria das Graças, Sevastsyanovich, Yanina R., Tveen Jensen, Karina, Browning, Douglas F., Scott-Tucker, Anthony and Henderson, Ian R. (2010). The unusual extended signal peptide region is not required for secretion and function of an Escherichia coli autotransporter. FEMS Microbiology Letters, 311 (2), 133-139. doi: 10.1111/j.1574-6968.2010.02081.x

Lehr, U., Schütz, M., Oberhettinger, P., Ruiz-Perez, F., Donald, J. W., Palmer, T., Linke, D., Henderson, I. R. and Autenrieth, I. B. (2010). C-terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA: YadA is recognized and assembled by the BAM complex. Molecular Microbiology, 78 (4), 932-946. doi: 10.1111/j.1365-2958.2010.07377.x

Ruiz-Perez, Fernando, Henderson, Ian R. and Nataro, James P. (2010). Interaction of FkpA, a peptidyl-prolyl cis/trans isomerase with EspP autotransporter protein. Gut Microbes, 1 (5), 339-344. doi: 10.4161/gmic.1.5.13436

Knowles, Timothy J., Sridhar, Pooja, Rajesh, Sandya, Manoli, Eleni, Overduin, Michael and Henderson, Ian R. (2010). Secondary structure and 1H, 13C and 15N resonance assignments of BamE, a component of the outer membrane protein assembly machinery in Escherichia coli. Biomolecular NMR Assignments, 4 (2), 179-181. doi: 10.1007/s12104-010-9236-7

Chaudhuri, Roy R., Sebaihia, Mohammed, Hobman, Jon L., Webber, Mark A., Leyton, Denisse L., Goldberg, Martin D., Cunningham, Adam F., Scott-Tucker, Anthony, Ferguson, Paul R., Thomas, Christopher M., Frankel, Gad, Tang, Christoph M., Dudley, Edward G., Roberts, Ian S., Rasko, David A., Pallen, Mark J., Parkhill, Julian, Nataro, James P., Thomson, Nicholas R. and Henderson, Ian R. (2010). Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS ONE, 5 (1) e8801, e8801. doi: 10.1371/journal.pone.0008801

Ruiz-Perez, Fernando, Henderson, Ian R., Leyton, Denisse L., Rossiter, Amanda E., Zhang, Yinghua and Nataro, James P. (2009). Roles of periplasmic chaperone proteins in the biogenesis of serine protease autotransporters of Enterobacteriaceae. Journal of Bacteriology, 191 (21), 6571-6583. doi: 10.1128/JB.00754-09

Ward, R., Zoltner, M., Beer, L., El Mkami, H., Henderson, I. R., Palmer, T. and Norman, D. G. (2009). The Orientation of a Tandem POTRA Domain Pair, of the Beta-Barrel Assembly Protein BamA, Determined by PELDOR Spectroscopy. Structure, 17 (9), 1187-1194. doi: 10.1016/j.str.2009.07.011

Berger, Cedric N., Shaw, Robert K., Ruiz-Perez, Fernando, Nataro, James P., Henderson, Ian R., Pallen, Mark J. and Frankel, Gad (2009). Interaction of enteroaggregative Escherichia coli with salad leaves. Environmental Microbiology Reports, 1 (4), 234-239. doi: 10.1111/j.1758-2229.2009.00037.x

Desvaux, Mickaël, Hébraud, Michel, Talon, Régine and Henderson, Ian R. (2009). Outer membrane translocation: numerical protein secretion nomenclature in question in mycobacteria. Trends in Microbiology, 17 (8), 338-340. doi: 10.1016/j.tim.2009.05.008

Knowles, Timothy J., McClelland, Darren M., Rajesh, Sandya, Henderson, Ian R. and Overduin, Michael (2009). Secondary structure and 1H, 13C and 15N backbone resonance assignments of BamC, a component of the outer membrane protein assembly machinery in Escherichia coli. Biomolecular NMR Assignments, 3 (2), 203-206. doi: 10.1007/s12104-009-9175-3

Gil-Cruz, Cristina, Bobat, Saeeda, Marshall, Jennifer L., Kingsley, Robert A., Ross, Ewan A., Henderson, Ian R., Leyton, Denisse L., Coughlan, Ruth E., Khan, Mahmood, Jensen, Karina T., Buckley, Christopher D., Dougan, Gordon, MacLennan, Ian C. M., López-Macías, Constantino and Cunningham, Adam F. (2009). The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response. Proceedings of the National Academy of Sciences of the United States of America, 106 (24), 9803-9808. doi: 10.1073/pnas.0812431106

Harrington, S. M., Sheikh, J., Henderson, I. R., Ruiz-Perez, F., Cohen, P. S. and Nataro, J. P. (2009). The Pic Protease of Enteroaggregative Escherichia coli Promotes Intestinal Colonization and Growth in the Presence of Mucin. Infection and Immunity, 77 (6), 2465-2473. doi: 10.1128/iai.01494-08

Desvaux, Mickaël, Hébraud, Michel, Talon, Régine and Henderson, Ian R. (2009). Secretion and subcellular localizations of bacterial proteins: a semantic awareness issue. Trends in Microbiology, 17 (4), 139-145. doi: 10.1016/j.tim.2009.01.004

Knowles, Timothy J., Scott-Tucker, Anthony, Overduin, Michael and Henderson, Ian R. (2009). Membrane protein architects: the role of the BAM complex in outer membrane protein assembly. Nature Reviews Microbiology, 7 (3), 206-214. doi: 10.1038/nrmicro2069

Iguchi, Atsushi, Thomson, Nicholas R., Ogura, Yoshitoshi, Saunders, David, Ooka, Tadasuke, Henderson, Ian R., Harris, David, Asadulghani, M., Kurokawa, Ken, Dean, Paul, Kenny, Brendan, Quail, Michael A., Thurston, Scott, Dougan, Gordon, Hayashi, Tetsuya, Parkhill, Julian and Frankel, Gad (2009). Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69. Journal of Bacteriology, 91 (1), 347-354. doi: 10.1128/JB.01238-08

Rasko, David A., Rosovitz, M. J., Myers, Garry S. A., Mongodin, Emmanuel F., Fricke, W. Florian, Gajer, Pawel, Crabtree, Jonathan, Sebaihia, Mohammed, Thomson, Nicholas R., Chaudhuri, Roy, Henderson, Ian R., Sperandio, Vanessa and Ravel, Jacques (2008). The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates. Journal of Bacteriology, 190 (20), 6881-6893. doi: 10.1128/JB.00619-08

Yen, Yihfen T., Kostakioti, Maria, Henderson, Ian R. and Stathopoulos, Christos (2008). Common themes and variations in serine protease autotransporters. Trends in Microbiology, 16 (8), 370-9. doi: 10.1016/j.tim.2008.05.003

de Luna, Maria das Gracas, Scott-Tucker, Anthony, Desvaux, Mickael, Ferguson, Paul, Morin, Nicholas P., Dudley, Edward G., Turner, Sue, Nataro, James P., Owen, Peter and Henderson, Ian R. (2008). The Escherichia coli biofilm-promoting protein Antigen 43 does not contribute to intestinal colonization. FEMS Microbiology Letters, 284 (2), 237-246. doi: 10.1111/j.1574-6968.2008.01207.x

Knowles, Timothy J., Jeeves, Mark, Bobat, Saeeda, Dancea, Felician, McClelland, Darren, Palmer, Tracy, Overduin, Michael and Henderson, Ian R. (2008). Fold and function of polypeptide transport-associated domains responsible for delivering unfolded proteins to membranes. Molecular Microbiology, 68 (5), 1216-1227. doi: 10.1111/j.1365-2958.2008.06225.x

van der Woude, Marjan W. and Henderson, Ian R. (2008). Regulation and function of Ag43 (Flu). Annual Review of Microbiology, 62 (1), 153-169. doi: 10.1146/annurev.micro.62.081307.162938

Knowles, Timothy J., Bobat, Saeeda, Jeeves, Mark, Henderson, Ian R. and Overduin, Michael (2007). Secondary structure and 1H, 13C and 15N resonance assignments of the Escherichia coli YaeT POTRA domain. Biomolecular NMR Assignments, 1 (1), 113-115. doi: 10.1007/s12104-007-9032-1

Cunningham, Adam F., Gaspal, Fabrina, Serre, Karine, Mohr, Elodie, Henderson, Ian R., Scott-Tucker, Anthony, Kenny, Sinead M., Khan, Mahmood, Toellner, Kai-Michael, Lane, Peter J. L. and MacLennan, Ian C. M. (2007). Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection. Journal of Immunology, 178 (10), 6200-6207. doi: 10.4049/jimmunol.178.10.6200

Desvaux, Mickaël, Scott-Tucker, Anthony, Turner, Sue M., Cooper, Lisa M., Huber, Damon, Nataro, James P. and Henderson, Ian R. (2007). A conserved extended signal peptide region directs posttranslational protein translocation via a novel mechanism. Microbiology, 153 (1), 59-70. doi: 10.1099/mic.0.29091-0

Turner, Sue M., Chaudhuri, Roy R., Jiang, Zhi-Dong, DuPont, Herbert, Gyles, Carlton, Penn, Charles W., Pallen, Mark J. and Henderson, Ian R. (2006). Phylogenetic comparisons reveal multiple acquisitions of the toxin genes by enterotoxigenic Escherichia coli strains of different evolutionary lineages. Journal of Clinical Microbiology, 44 (12), 4528-4536. doi: 10.1128/JCM.01474-06

Desvaux, Mickaël, Cooper, Lisa M., Filenko, Nina A., Scott-Tucker, Anthony, Turner, Sue M., Cole, Jeffrey A. and Henderson, Ian R. (2006). The unusual extended signal peptide region of the type V secretion system is phylogenetically restricted. FEMS Microbiology Letters, 264 (1), 22-30. doi: 10.1111/j.1574-6968.2006.00425.x

Turner, Susan M., Scott-Tucker, Anthony, Cooper, Lisa M. and Henderson, Ian R. (2006). Weapons of mass destruction: virulence factors of the global killer enterotoxigenic Escherichia coli. FEMS Microbiology Letters, 263 (1), 10-20. doi: 10.1111/j.1574-6968.2006.00401.x

Desvaux, Mickaël, Hébraud, Michel, Henderson, Ian R. and Pallen, Mark J. (2006). Type III secretion: what's in a name?. Trends in Microbiology, 14 (4), 157-160. doi: 10.1016/j.tim.2006.02.009

Henderson, Ian R. and Nataro, James P. (2005). Autotransporter proteins. EcoSal Plus, 1 (2) ecosalplus.8.7.3. doi: 10.1128/ecosalplus.8.7.3

Desvaux, Mickaël, Khan, Arshad, Scott-Tucker, Anthony, Chaudhuri, Roy R., Pallen, Mark J. and Henderson, Ian R. (2005). Genomic analysis of the protein secretion systems in Clostridium acetobutylicum ATCC 824. Biochimica et Biophysica Acta - Molecular Cell Research, 1745 (2), 223-253. doi: 10.1016/j.bbamcr.2005.04.006

Parham, N.J., Pollard, S.J., Desvaux, M., Scott-Tucker, A., Liu, C.J., Fivian, A. and Henderson, I.R. (2005). Distribution of the serine protease autotransporters of the Enterobacteriaceae among extraintestinal clinical isolates of Escherichia coli. Journal of Clinical Microbiology, 43 (8), 4076-4082. doi: 10.1128/JCM.43.8.4076-4082.2005

Desvaux, Mickaël, Khan, Arshad, Beatson, Scott A., Scott-Tucker, Anthony and Henderson, Ian R. (2005). Protein secretion systems in Fusobacterium nucleatum: Genomic identification of Type 4 piliation and complete Type V pathways brings new insight into mechanisms of pathogenesis. Biochimica Et Biophysica Acta-biomembranes, 1713 (2), 92-112. doi: 10.1016/j.bbamem.2005.05.002

Parham, Nick J., Pollard, Samantha J., Chaudhuri, Roy R., Beatson, Scott A., Desvaux, Mickaël, Russell, Michael A., Ruiz, Joaquim, Fivian, Amanda, Vila, Jordi and Henderson, Ian R. (2005). Prevalence of pathogenicity island IICFT073 genes among extraintestinal clinical isolates of Escherichia coli. Journal of Clinical Microbiology, 43 (5), 2425-2434. doi: 10.1128/JCM.43.5.2425-2434.2005

Henderson, I.R., Navarro-Garcia, F., Desvaux, M., Fernandez, R.C. and Ala'Aldeen, D. (2004). Type V protein secretion pathway: the autotransporter story. Microbiology and Molecular Biology Reviews, 68 (4), 692-744. doi: 10.1128/MMBR.68.4.692-744.2004

Desvaux, Mickaël, Parham, Nicholas J., Scott-Tucker, Anthony and Henderson, Ian R. (2004). The general secretory pathway: A general misnomer?. Trends in Microbiology, 12 (7), 306-309. doi: 10.1016/j.tim.2004.05.002

Desvaux, M., Parham, N.J. and Henderson, I.R. (2004). Type V protein secretion: simplicity gone awry?. Current Issues in Molecular Biology, 6 (2), 111-124.

Desvaux, M., Parham, N.J. and Henderson, I.R. (2004). The autotransporter secretion system. Research in Microbiology, 155 (2), 53-60. doi: 10.1016/j.resmic.2003.10.002

Parham, Nick J., Srinivasan, Usha, Desvaux, Mickaël, Foxman, Betsy, Marrs, Carl F. and Henderson, Ian R. (2004). PicU, a second serine protease autotransporter of uropathogenic Escherichia coli. FEMS Microbiology Letters, 230 (1), 73-83. doi: 10.1016/S0378-1097(03)00862-0

Desvaux, Mickaël, Parham, Nicholas J. and Henderson, Ian R. (2003). Secretory system in Gram negative bacterium type V Le système de sécrétion de type V chez les bactéries Gram-négatives. Biofutur (237), 34-37.

Pallen, Mark J., Chaudhuri, Roy R. and Henderson, Ian R. (2003). Genomic analysis of secretion systems. Current Opinion in Microbiology, 6 (5), 519-527. doi: 10.1016/j.mib.2003.09.005

Sheikh, Jalaluddin, Czeczulin, John, Harrington, Susan, Hicks, Susan, Henderson, Ian R., Le Bouguenec, Chantal, Gounon, Pierre, Phillips, Alan and Nataro, James P. (2002). A novel dispersin protein in enteroaggregative Escherichia coli. Journal of Clinical Investigation, 110 (9), 1329-1337. doi: 10.1172/JCI16172

Henderson, IR and Lam, AC (2001). Polymorphic proteins of Chlamydia spp. - autotransporters beyond the Proteobacteria. Trends in Microbiology, 9 (12), 573-578. doi: 10.1016/S0966-842X(01)02234-X

Henderson, Ian R. and Nataro, James P. (2001). Virulence functions of autotransporter proteins. Infection and Immunity, 69 (3), 1231-1243. doi: 10.1128/IAI.69.3.1231-1243.2001

Henderson, Ian R., Cappello, Renato and Nataro, James P. (2000). Autotransporter proteins, evolution and redefining protein secretion. Trends in Microbiology, 8 (12), 529-532. doi: 10.1016/S0966-842X(00)01853-9

Vila, J., Vargas, M., Henderson, I.R., Gascon, J. and Nataro, J.P. (2000). Enteroaggregative Escherichia coli virulence factors in traveler's diarrhea strains. Journal of Infectious Diseases, 182 (6), 1780-1783. doi: 10.1086/317617

Henderson, Ian R., Cappello, Renat and Nataro, James P. (2000). Autotransporter proteins, evolution and redefining protein secretion: response. Trends in Microbiology, 8 (12), 534-535. doi: 10.1016/S0966-842X(00)01884-9

Guyer, Debra M., Henderson, Ian R., Nataro, James P. and Mobley, Harry L. T. (2000). Identification of Sat, an autotransporter toxin produced by uropathogenic Escherichia coli. Molecular Microbiology, 38 (1), 53-66. doi: 10.1046/j.1365-2958.2000.02110.x

Henderson, Ian R., Nataro, James P., Kaper, James B., Meyer, Thomas F., Farrand, Stephen K., Burns, Drusilla L., Finlay, B. Brett and St Gene, Joseph W. (2000). Renaming protein secretion in the Gram-negative bacteria. Trends in Microbiology, 8 (8), 352-352. doi: 10.1016/S0966-842X(00)01814-X

Al-Hasani, Keith, Henderson, Ian R., Sakellaris, Harry, Rajakumar, Kumar, Grant, Travis, Nataro, James P., Robins-Browne, Roy and Adler, Ben (2000). The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation. Infection and Immunity, 68 (5), 2457-2463. doi: 10.1128/IAI.68.5.2457-2463.2000

Vila, Jordi, Vargas, Martha, Henderson, Ian R., Gascon, Joaquim and Nataro, James (2000). Human immunodeficiency virus type 1 infection is associated with significant mucosal inflammation characterized by increased expression of CCR5, CXCR4, and β-chemokines. Journal of Infectious Diseases, 182 (6), 1625-1635. doi: 10.1086/317625

Henderson, I. R., Czeczulin, J., Eslava, C., Noriega, F. and Nataro, J. P. (1999). Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infection and Immunity, 67 (11), 5587-5596.

Henderson, I. R., Hicks, S., Navarro-Garcia, F., Elias, W. P., Philips, A. D. and Nataro, J. P. (1999). Involvement of the enteroaggregative Escherichia coli plasmid-encoded toxin in causing human intestinal damage. Infection and Immunity, 67 (10), 5338-5344.

Henderson, I.R., Owen, P. and Nataro, J.P. (1999). Molecular switches - the ON and OFF of bacterial phase variation. Molecular Microbiology, 33 (5), 919-932. doi: 10.1046/j.1365-2958.1999.01555.x

Henderson, Ian R. and Nataro, James P. (1999). A conserved motif in the hexosyltransferases. Molecular Microbiology, 33 (1), 222-222. doi: 10.1046/j.1365-2958.1999.01447.x

Czeczulin, J., Whittam, T. S., Henderson, I. R., Navarro-Garcia, F. and Nataro, J. P. (1999). Phylogenetic analysis of enteroaggregative and diffusely adherent Escherichia coli. Infection and Immunity, 67 (6), 2692-2699.

Henderson, I. R. and Owen, P. (1999). The major phase-variable outer membrane protein of Escherichia coli structurally resembles the immunoglobulin A1 protease class of exported protein and is regulated by a novel mechanism involving Dam and OxyR. Journal of Bacteriology, 181 (7), 2132-2141.

Elias, WP, Czeczulin,, Henderson, IR, Trabulsi, LR and Nataro, JP (1999). Organization of biogenesis genes for aggregative adherence fimbria II defines a virulence gene cluster in enteroaggregative Escherichia coli. Journal of Bacteriology, 181 (6), 1779-1785.

Henderson, Ian R., Navarro-Garcia, Fernando and Nataro, James P. (1998). The great escape: structure and function of the autotransporter proteins. Trends in Microbiology, 6 (9), 370-378. doi: 10.1016/S0966-842X(98)01318-3

Eslava, C., Navarro-Garcia, F., Czeczulin, J.R., Henderson, I.R., Cravioto, A. and Nataro, J.P. (1998). Pet, an autotransporter enterotoxin from enteroaggregative Escherichia coli. Infection and Immunity, 66 (7), 3155-3163.

Henderson, Ian R., Meehan, Mary and Owen, Peter (1997). A novel regulatory mechanism for a novel phase-variable outer membrane protein of Escherichia coli. Advances in Experimental Medicine and Biology, 412, 349-355.

Henderson, Ian and Owen, Peter (1997). The autoregulatory protein Mor and OxyR are identical. Microbiology, 143 (5), 1482-1482. doi: 10.1099/00221287-143-5-1482

Henderson, Ian R., Meehan, Mary and Owen, Peter (1997). Antigen 43, a phase-variable bipartite outer membrane protein, determines colony morphology and autoaggregation in Escherichia coli K-12. FEMS Microbiology Letters, 149 (1), 115-120. doi: 10.1111/j.1574-6968.1997.tb10317.x

Owen, Peter, Meehan, Mary, de Loughry-Doherty, Helen and Henderson, Ian (1996). Phase-variable outer membrane proteins inEscherichia coli. FEMS Immunology & Medical Microbiology, 16 (2), 63-76. doi: 10.1111/j.1574-695x.1996.tb00124.x

Henderson, Ian R. , Meehan, Mary and Owen, Peter (1997). A novel regulatory mechanism for a novel phase-variable outer membrane protein of Escherichia coli. 1st International Rushmore Conference on Mechanisms in the Pathogenesis of Enteric Diseases, Rapid City, SD, United States, 28-30 September 1995. New York, United States: Springer . doi: 10.1007/978-1-4899-1828-4_56

Owen, Peter, Meehan, Mary, De Loughry-Doherty, Helen and Henderson, Ian (1996). Phase-variable outer membrane proteins in Escherichia coli. doi: 10.1016/S0928-8244(96)00069-7

Professor Ian Henderson

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