Researcher biography

Sohye Yoon joined the Genome Innovation Hub in 2018 after 7 years at the Scottish Fish Immunology Research Centre (SFIRC) at University of Aberdeen, UK. At the SFIRC, she attained comprehensive knowledge in immunology and utilised a wide variety of methods in the areas of molecular biology, engineering monoclonal antibodies and recombinant proteins and sequencing analysis to develop the necessary assays for her PhD and 2 post-doctoral projects.

 

Since coming to the GIH, she has expanded her research capabilities into Genomics area with her strong competence in molecular biology. Sohye successfully optimised and developed Cap Analysis Gene Expression (CAGE) RNA seq assay, which is a 5’ sequencing tag technology and is yet to be developed at UQ or in Australia. She is currently working on developing and implementing novel and emerging platforms in the area of single cell genomics with particular focus on introducing a plate-based single-cell 3’ library preparation method with low number of input cells. One of her other main research area with an external collaborator group is to exploit spatial genomics technologies in tissue contexts, such as RNAscope assay with her growing expertise in microscopy image analysis.

Featured projects Duration
Quantitative transcriptome analysis (CAGE)
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Spatial genomics technologies to study cancer and genetic diseases in tissue contexts
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Automated single cell quantitative in situ gene expression in cells and tissues (AutoMerFISH)
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Understanding host-pathogen interactions through development of new co-transcriptomic single cell RNA sequencing technologies
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Single-cell transcriptome and chromatin profiling in plant cells
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Combining novel scSLAM-seq technology with 10x Genomics Chromium to track microchanges in newly synthesised RNA
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Simultaneous identification of RNA-chromatin interactions and transcriptomes in single cells
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Genome-Phaser: protocol for fully phasing whole genome variants using haplotagging
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Developing new "spatial omics" capabilities
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Enabling population scale epigenomics for crop improvement
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021