Subash’s work at GIH focuses on long read sequencing technologies such as Oxford Nanopore and PacBio Sequel. With his troubleshooting experiences and multi-disciplinary skills, he helps internal and external collaborators to develop and optimise methods for sample and library preparation to tune innovative and optimal use of long read sequencing technologies.

Researcher biography

Subash completed a BSc in Biotechnology and Genetic Engineering in Bangladesh in 2007. He returned to Nepal and worked as a research technician for 2 years before moving to the Netherlands to complete his MSc in Biotechnology in 2011. He then moved to Germany, where he worked in a Biotechnology company, Riboxx GmbH for 3 years before completing his doctorate degree (dr.rer.medic) in virology from Technical University of Dresden in 2015. His work characterising viral proteins and RNA regulatory elements resulted in the identification of two potential antiviral drug-targets for pre-clinical antiviral drug development studies. Before joining GIH in 2018, he worked with Prof. Richard Lewis at IMB where his work focused on cone snails venom genomics and transcriptomics.

Featured projects Duration
Discovery of new regulatory networks with long-read transcriptomics
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Applying long-read sequencing technology to understand telomere repair and DNA replication
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
Assembly of complex genome (Macadamia) using single molecule sequencing
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2019
A genomic dissection of metaorganisms: molecular approaches for teasing apart the hologenome
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Targeted capture and detection of 16s rRNA gene applying PCR free long read sequencing
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2020
Optimising Nanopore sequencing methylation analysis in cell-free DNA
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Genome-Phaser: protocol for fully phasing whole genome variants using haplotagging
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021
Assessing DNA Replication Dynamics in Cancer
Genome Innovation Hub Collaborative Project (UQ infrastructure)
2021

Areas of research